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Cancer Biology

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  • Targeting glutamine metabolism and redox state for leukemia therapy
    Mark A. Gregory, Travis Nemkov, Vadym Zaberezhnyy, Hae J. Park, Sarah Gehrke, Kirk C. Hansen, Angelo D’Alessandro, James DeGregori
    bioRxiv 303529; doi: https://doi.org/10.1101/303529
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  • Intra-tumor heterogeneity defines treatment-resistant HER2+ breast tumors
    Inga H. Rye, Anne Trinh, Anna Sætersdal, Daniel Nebdal, Ole Christian Lingjærde, Vanessa Almendro, Kornelia Polyak, Anne-Lise Børresen-Dale, Åslaug Helland, Florian Markowetz, Hege G. Russnes
    bioRxiv 297549; doi: https://doi.org/10.1101/297549
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  • Integrative analysis of DNA methylation suggests down-regulation of oncogenic pathways and reduced de-novo mutation in survival outliers of glioblastoma
    Taeyoung Hwang, Dimitrios Mathios, Kerrie L McDonald, Irene Daris, Sung-Hye Park, Peter C Burger, Sojin Kim, Yun-Sik Dho, Hruban Carolyn, Chetan Bettegowda, Joo Heon Shin, Michael Lim, Chul-Kee Park
    bioRxiv 302042; doi: https://doi.org/10.1101/302042
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  • What does not kill a tumour may make it stronger: in silico Insights into Chemotherapeutic Drug Resistance
    Sara Hamis, Perumal Nithiarasu, Gibin G Powathil
    bioRxiv 230318; doi: https://doi.org/10.1101/230318 Confirmatory Results
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  • Nonlinear dynamics of chemotherapeutic resistance
    Y. Ma, P.K. Newton
    bioRxiv 300582; doi: https://doi.org/10.1101/300582
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  • A novel xenograft model reveals invasive mesenchymal transition and ineffective angiogenic response during anti-angiogenic therapy resistance
    Arman Jahangiri, William Chen, Ankush Chandra, Alan Nguyen, Garima Yagnik, Jacob Weiss, Kayla J. Wolf, Jung-Ming G. Lin, Soeren Mueller, Jonathan Rick, Maxim Sidorov, Patrick Flanigan, W. Shawn Carbonell, Aaron Diaz, Luke Gilbert, Sanjay Kumar, Manish K. Aghi
    bioRxiv 272328; doi: https://doi.org/10.1101/272328
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  • Analytical Validation of Multiplex Biomarker Assay to Stratify Colorectal Cancer Samples into Molecular Subtypes
    Chanthirika Ragulan, Katherine Eason, Elisa Fontana, Gift Nyamundanda, Yatish Patil, Pawan Poudel, Rita T. Lawlor, Maguy Del Rio, Koo Si-Lin, Tan Wah Siew, Francesco Sclafani, Ruwaida Begum, Larissa S. Teixeira Mendes, Pierre Martineau, Aldo Scarpa, Iain Beehuat Tan, David Cunningham, Anguraj Sadanandam
    bioRxiv 174847; doi: https://doi.org/10.1101/174847
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  • The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease
    Lindsay Kosack, Bettina Wingelhofer, Alexandra Popa, Bojan Vilagos, Anna Orlova, Peter Majek, Katja Parapatics, Alexander Lercher, Benedikt Agerer, Anna Ringler, Johanna Klughammer, Mark Smyth, Kseniya Khamina, Hatoon Baazim, David A. Rosa, Jisung Park, Patrick T. Gunning, Christoph Bock, Hannah V. Siddle, Stefan Kubicek, Elizabeth P. Murchison, Keiryn L. Bennett, Richard Moriggl, Andreas Bergthaler
    bioRxiv 283309; doi: https://doi.org/10.1101/283309
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  • Ras Suppresses TXNIP Expression by Restricting Ribosome Translocation
    Zhizhou Ye, Donald E. Ayer
    bioRxiv 299354; doi: https://doi.org/10.1101/299354
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  • Aberrant splicing in B-cell acute lymphoblastic leukemia
    Kathryn L. Black, Ammar S. Naqvi, Katharina E. Hayer, Scarlett Y. Yang, Elisabeth Gillespie, Asen Bagashev, Vinodh Pillai, Sarah K. Tasian, Matthew R. Gazzara, Martin Carroll, Deanne Taylor, Kristen W. Lynch, Yoseph Barash, Andrei Thomas-Tikhonenko
    bioRxiv 225136; doi: https://doi.org/10.1101/225136
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