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Cancer Biology

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  • High throughput proteomics identifies 484 high-accuracy plasma protein biomarker signatures for ovarian cancer
    Stefan Enroth, Malin Berggrund, Maria Lycke, John Broberg, Martin Lundberg, Erika Assarsson, Matts Olovsson, Karin Stålberg, Karin Sundfeldt, Ulf Gyllensten
    bioRxiv 349829; doi: https://doi.org/10.1101/349829
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  • Prognostic Relevance of CCDC88C (Daple) Transcripts in the Peripheral Blood of Patients with Malignant Melanoma
    Ying Dunkel, Anna L. Reid, Jason Ear, Nicolas Aznar, Michael Millward, Elin Gray, Robert Pearce, Melanie Ziman, Pradipta Ghosh
    bioRxiv 346551; doi: https://doi.org/10.1101/346551
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  • WDR5 regulates epithelial-to-mesenchymal transition in breast cancer cells via TGFβ
    Punzi Simona, Balestrieri Chiara, D’Alesio Carolina, Bossi Daniela, Dellino Gaetano Ivan, Gatti Elena, Pruneri Giancarlo, Criscitiello Carmen, Carugo Alessandro, Curigliano Giuseppe, Natoli Gioacchino, Pelicci Pier Giuseppe, Lanfrancone Luisa
    bioRxiv 348532; doi: https://doi.org/10.1101/348532
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  • Androgen Receptor-Induced Integrin α6β1 and Adhesion to Laminin Promotes Survival and Drug Resistance in Castration-Resistant Prostate Cancer through BNIP3
    Eric A. Nollet, Sourik S. Ganguly, Veronique V. Schulz, Anne Cress, Cindy K. Miranti
    bioRxiv 349050; doi: https://doi.org/10.1101/349050
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  • A Stochastic Model of Metastatic Bottleneck Predicts Patient Outcome and Therapy Response
    Ewa Szczurek, Tyll Krueger, Barbara Klink, Niko Beerenwinkel
    bioRxiv 348086; doi: https://doi.org/10.1101/348086
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  • IQGAP3 Overexpression Correlates with Poor Prognosis and Radiation Therapy Resistance in Breast Cancer
    Xin Hua, Zhi-Qing Long, Wen-Wen Zhang, Chao Lin, Xiao-Qing Sun, Wen Wen, Zi-Jian Lu, Na Guo, Zhen-Yu He, Li Bing-Song, Ling Guo, Huan-Xin Lin
    bioRxiv 346163; doi: https://doi.org/10.1101/346163
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  • Dynamics and predicted drug response of a gene network linking dedifferentiation with β-catenin dysfunction in hepatocellular carcinoma
    Claude Gérard, Mickaël Di-Luoffo, Léolo Gonay, Stefano Caruso, Gabrielle Couchy, Axelle Loriot, Junyan Tao, Katarzyna Konobrocka, Sabine Cordi, Satdarshan P. Monga, Emmanuel Hanert, Jessica Zucman-Rossi, Frédéric P. Lemaigre
    bioRxiv 347666; doi: https://doi.org/10.1101/347666
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  • G-quadruplex DNA drives genomic instability and represents a targetable molecular abnormality in ATRX-deficient malignant glioma
    Yuxiang Wang, Jie Yang, Wei Wu, Rachna Shah, Carla Danussi, Gregory J. Riggins, Kasthuri Kannan, Erik P. Sulman, Timothy A. Chan, Jason T. Huse
    bioRxiv 347542; doi: https://doi.org/10.1101/347542
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  • Humanized Mcl-1 mice enable accurate pre-clinical evaluation of MCL-1 inhibitors destined for clinical use
    Margs S. Brennan, Catherine Chang, Grant Dewson, Lin Tai, Guillaume Lessene, Andreas Strasser, Gemma L. Kelly, Marco J. Herold
    bioRxiv 335430; doi: https://doi.org/10.1101/335430
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  • Distinct Microbes, Metabolites, and Ecologies Define the Microbiome in Deficient and Proficient Mismatch Repair Colorectal Cancers
    Vanessa L. Hale, Patricio Jeraldo, Jun Chen, Michael Mundy, Janet Yao, Sambhawa Priya, Gary Keeney, Kelly Lyke, Jason Ridlon, Bryan A. White, Amy J. French, Stephen N. Thibodeau, Christian Diener, Osbaldo Resendis-Antonio, Jaime Gransee, Tumpa Dutta, Xuan-Mai Petterson, Ran Blekhman, Lisa Boardman, David Larson, Heidi Nelson, Nicholas Chia
    bioRxiv 346510; doi: https://doi.org/10.1101/346510
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