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  • Identification of Subsets of Genetic Alterations in KRAS-mutant Lung Cancer using Association Rule Mining
    Junior Tayou
    bioRxiv 235390; doi: https://doi.org/10.1101/235390
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  • In-depth characterization of the cisplatin mutational signature in human cell lines and in esophageal and liver tumors
    Arnoud Boot, Mi Ni Huang, Alvin W.T. Ng, Szu-Chi Ho, Jing Quan Lim, Yoshiiku Kawakami, Kazuaki Chayama, Bin Tean Teh, Hidewaki Nakagawa, Steven G. Rozen
    bioRxiv 189233; doi: https://doi.org/10.1101/189233
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  • An antisense RNA capable of modulating the expression of the tumor suppressor microRNA-34a
    Jason T. Serviss, Felix Clemens Richter, Jimmy Van den Eynden, Nathanael Andrews, Miranda Houtman, Mattias Vesterlund, Laura Schwarzmueller, Per Johnsson, Erik Larsson, Dan Grandér, Katja Pokrovskaja Tamm
    bioRxiv 234310; doi: https://doi.org/10.1101/234310
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  • Macrophage-derived granulin drives resistance to immune checkpoint inhibition in metastatic pancreatic cancer
    Valeria Quaranta, Carolyn Rainer, Sebastian R. Nielsen, Meirion Raymant, Muhammad Shamsher Ahmed, Dannielle D. Engle, Arthur Taylor, Trish Murray, Fiona Campbell, Daniel Palmer, David A. Tuveson, Ainhoa Mielgo, Michael C. Schmid
    bioRxiv 234906; doi: https://doi.org/10.1101/234906
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  • Alterations in Cell Motility, Proliferation, and Metabolism in Novel Models of Acquired Temozolomide Resistant Glioblastoma
    DM Tiek, JD Rone, GT Graham, EL Pannkuk, BR Haddad, RB Riggins
    bioRxiv 232447; doi: https://doi.org/10.1101/232447
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  • The landscape of actionable genomic alterations in cell-free circulating tumor DNA from 21,807 advanced cancer patients
    Oliver A. Zill, Kimberly C. Banks, Stephen R. Fairclough, Stefanie A. Mortimer, James V. Vowles, Reza Mokhtari, David R. Gandara, Philip C. Mack, Justin I. Odegaard, Rebecca J. Nagy, Arthur M. Baca, Helmy Eltoukhy, Darya I. Chudova, Richard B. Lanman, AmirAli Talasaz
    bioRxiv 233205; doi: https://doi.org/10.1101/233205
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  • Genetic and cellular sensitivity of Caenorhabditis elegans to the chemotherapeutic agent cisplatin
    Francisco Javier García-Rodríguez, Carmen Martínez-Fernández, David Brena, Ernest Nadal, Mike Boxem, Sebastian Honnen, Antonio Miranda-Vizuete, Alberto Villanueva, Julián Cerón
    bioRxiv 233023; doi: https://doi.org/10.1101/233023
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  • Clinically Important sex differences in GBM biology revealed by analysis of male and female imaging, transcriptome and survival data
    Wei Yang, Nicole M. Warrington, Sara J. Taylor, Eduardo Carrasco, Kyle W. Singleton, Ningying Wu, Justin D. Lathia, Michael E. Berens, Albert H. Kim, Jill S. Barnholtz-Sloan, Kristin R. Swanson, Jingqin Luo, Joshua B Rubin
    bioRxiv 232744; doi: https://doi.org/10.1101/232744
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  • The Activation of MEK1 by Enhanced Homodimerization Drives Tumorigenesis
    Jimin Yuan, Wan Hwa Ng, Zizi Tian, Jiajun Yap, Manuela Baccarini, Zhongzhou Chen, Jiancheng Hu
    bioRxiv 229849; doi: https://doi.org/10.1101/229849
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  • DARPP-32 and t-DARPP promote lung cancer growth through IKKα-dependent cell migration and Akt/Erk-mediated cell survival
    Sk. Kayum Alam, Matteo Astone, Ping Liu, Stephanie R. Hall, Abbygail M. Coyle, Erin N. Dankert, Dane K. Hoffman, Wei Zhang, Rui Kuang, Anja C. Roden, Aaron S. Mansfield, Luke H. Hoeppner
    bioRxiv 229658; doi: https://doi.org/10.1101/229658
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