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Cancer Biology

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  • Candidate urine biomarker discovery from only five pairs of samples before and after tumor resection in glioma patients
    Jianqiang Wu, Jun Zhang, Yuanli Zhao, Youhe Gao
    bioRxiv 240861; doi: https://doi.org/10.1101/240861
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  • MYC-driven epigenetic reprogramming favors the onset of tumorigensis by inducing a stem cell-like state
    Vittoria Poli, Luca Fagnocchi, Alessandra Fasciani, Alessandro Cherubini, Stefania Mazzoleni, Sara Ferrillo, Annarita Miluzio, Gabriella Gaudioso, Valentina Vaira, Alice Turdo, Miriam Giaggianesi, Aurora Chinnici, Elisa Lipari, Silvio Bicciato, Silvano Bosari, Matilde Todaro, Alessio Zippo
    bioRxiv 241042; doi: https://doi.org/10.1101/241042
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  • A measure of vascular reactivity to overcome neurovascular uncoupling in functional imaging of brain tumors: initial results
    Henning U. Voss, Kyung K. Peck, Nicole M. Petrovich Brennan, Andrei I. Holodny
    bioRxiv 240085; doi: https://doi.org/10.1101/240085
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  • Modularity of the metabolic gene network as a prognostic biomarker for hepatocellular carcinoma
    Fengdan Ye, Dongya Jia, Mingyang Lu, Herbert Levine, Michael W Deem
    bioRxiv 224998; doi: https://doi.org/10.1101/224998
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  • The whole-genome panorama of cancer drivers
    Radhakrishnan Sabarinathan, Oriol Pich, Iñigo Martincorena, Carlota Rubio-Perez, Malene Juul, Jeremiah Wala, Steven Schumacher, Ofer Shapira, Nikos Sidiropoulos, Sebastian M. Waszak, David Tamborero, Loris Mularoni, Esther Rheinbay, Henrik Hornshøj, Jordi Deu-Pons, Ferran Muiños, Johanna Bertl, Qianyun Guo, Chad J. Creighton, Joachim Weischenfeldt, Jan O. Korbel, Gad Getz, Peter J. Campbell, Jakob S. Pedersen, Rameen Beroukhim, Abel Gonzalez-Perez, Núria López-Bigas, on behalf of the PCAWG Drivers and Functional Interpretation Group and the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Network
    bioRxiv 190330; doi: https://doi.org/10.1101/190330
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  • The PTPRT pseudo-phosphatase domain is a denitrase
    Yiqing Zhao, Shuliang Zhao, Yujun Hao, Benlian Wang, Peng Zhang, Xiujing Feng, Yicheng Chen, Jing Song, John Mieyal, Sanford Markowitz, Rob M. Ewing, Ronald A. Conlon, Masaru Miyagi, Zhenghe Wang
    bioRxiv 238980; doi: https://doi.org/10.1101/238980
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  • HNF1A is a Novel Oncogene and Central Regulator of Pancreatic Cancer Stem Cells
    Ethan V. Abel, Masashi Goto, Brian Magnuson, Saji Abraham, Nikita Ramanathan, Emily Hotaling, Anthony A. Alaniz, Chandan Kumar-Sinha, Michele L. Dziubinski, Sumithra Urs, Lidong Wang, Jiaqi Shi, Meghna Waghray, Mats Ljungman, Howard C. Crawford, Diane M. Simeone
    bioRxiv 238097; doi: https://doi.org/10.1101/238097
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  • Somatic Mutations Predict Acute Myeloid Leukemia Years Before Diagnosis
    Pinkal Desai, Nuria Mencia-Trinchant, Oleksandr Savenkov, Michael S. Simon, Gloria Cheang, Sangmin Lee, Michael Samuels, Ellen K Ritchie, Monica L. Guzman, Karla V Ballman, Gail J. Roboz, Duane C. Hassane
    bioRxiv 237941; doi: https://doi.org/10.1101/237941
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  • Challenges in Using ctDNA to Achieve Early Detection of Cancer
    Imran S Haque, Olivier Elemento
    bioRxiv 237578; doi: https://doi.org/10.1101/237578
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  • Lack of Evidence that Ursodeoxycholic Acid’s Effects on the Gut Microbiome Influence Colorectal Adenoma Risk
    Talima Pearson, J. Gregory Caporaso, Monica Yellowhair, Nicholas A. Bokulich, Denise J. Roe, Betsy C. Wertheim, Mark Linhart, Jessica A. Martinez, Cherae Bilagody, Heidie Hornstra, David S. Alberts, Peter Lance, Patricia A. Thompson
    bioRxiv 237495; doi: https://doi.org/10.1101/237495
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