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Cancer Biology

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  • ZNF191 Inhibits Hepatocellular Carcinoma Metastasis via DLG1-mediated YAP1 Inactivation
    Di Wu, Haitao Li, Yufeng Liu, Hexige Saiyin, Chenji Wang, Zhen Wei, Wenjiao Zen, Danyang Liu, Qi Chen, Haojie Huang, Guoyuan Liu, Songmin Jiang, Long Yu
    bioRxiv 027060; doi: https://doi.org/10.1101/027060
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  • Passenger DNA alterations reduce cancer fitness in cell culture and mouse models
    Christopher D McFarland, Julia A Yaglom, Jonathan W Wojtkowiak, Jacob G Scott, David L Morse, Michael Y Sherman, Leonid A Mirny
    bioRxiv 026302; doi: https://doi.org/10.1101/026302
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  • The landscape of T cell infiltration in human cancer and its association with antigen presenting gene expression
    Yasin Şenbabaoğlu, Andrew G. Winer, Ron S. Gejman, Ming Liu, Augustin Luna, Irina Ostrovnaya, Nils Weinhold, William Lee, Samuel D. Kaffenberger, Ying Bei Chen, Martin H. Voss, Jonathan A. Coleman, Paul Russo, Victor E. Reuter, Timothy A. Chan, Emily H. Cheng, David A. Scheinberg, Ming O. Li, James J. Hsieh, Chris Sander, A. Ari Hakimi
    bioRxiv 025908; doi: https://doi.org/10.1101/025908
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  • A comparative analysis of network mutation burdens across 21 tumor types augments discovery from cancer genomes
    Heiko Horn, Michael S. Lawrence, Jessica Xin Hu, Elizabeth Worstell, Nina Ilic, Yashaswi Shrestha, Eejung Kim, Atanas Kamburov, Alireza Kashani, William C. Hahn, Jesse S. Boehm, Gad Getz, Kasper Lage
    bioRxiv 025445; doi: https://doi.org/10.1101/025445
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  • Further genetic diversification in multiple tumors and an evolutionary perspective on therapeutics
    Yong Tao, Zheng Hu, Shaoping Ling, Shiou-Hwie Yeh, Weiwei Zhai, Ke Chen, Chunyan Li, Yu Wang, Kaile Wang, Hurng-Yi Wang, Eric A. Hungate, Kenan Onel, Jiang Liu, Changqing Zeng, Richard R. Hudson, Pei-Jer Chen, Xuemei Lu, Chung-I Wu
    bioRxiv 025429; doi: https://doi.org/10.1101/025429
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  • Why cancer cells have a more hyperpolarised mitochondrial membrane potential and emergent prospects for therapy
    Michael D Forrest Ph.D.
    bioRxiv 025197; doi: https://doi.org/10.1101/025197
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  • Comment on “Variation in cancer risk among tissues can be explained by the number of stem cell divisions”
    Maxime Tarabichi, Vincent Detours
    bioRxiv 024497; doi: https://doi.org/10.1101/024497 Contradictory Results
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  • An integrated transcriptomics and proteomics study of Head and Neck Squamous Cell Carcinoma – methodological and analytical considerations
    Anupama Rajan Bhat, Manoj Kumar Gupta, Priya Krithivasan, Kunal Dhas, Jayalakshmi Nair, Ram Bhupal Reddy, HV Sudheendra, Sandip Chavan, Harsha Vardhan, Sujatha Darsi, Lavanya Balakrishnan, Shanmukh Katragadda, Vikram Kekatpure, Amritha Suresh, Pramila Tata, Binay Panda, Moni A Kuriakose, Ravi Sirdeshmukh
    bioRxiv 024059; doi: https://doi.org/10.1101/024059
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  • SCT promoter methylation is a highly discriminative biomarker for lung and many other cancers
    Adwait Sathe, Yu-An Zhang, Xiaotu Ma, Pradipta Ray, Daniela Cadinu, Yi-Wei Wang, Xiao Yao, Xiaoyun Liu, Hao Tang, Yunfei Wang, Ying Huang, Changning Liu, Jin Gu, Martin Akerman, Yifan Mo, Chao Cheng, Zhenyu Xuan, Lei Chen, Guanghua Xiao, Yang Xie, Luc Girard, Hongyang Wang, Stephen Lam, Ignacio I Wistuba, Li Zhang, Adi F Gazdar, Michael Q Zhang
    bioRxiv 018515; doi: https://doi.org/10.1101/018515
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  • Gibbs Free Energy of Protein-Protein Interactions reflects tumor stage
    Edward A. Rietman, Alex Bloemendal, John Platig, Jack A. Tuszynski, Giannoula Lakka Klement
    bioRxiv 022491; doi: https://doi.org/10.1101/022491
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