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Cancer Biology

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  • Precise, pan-cancer discovery of gene fusions reveals a signature of selection in primary tumors
    Donald Eric Freeman, Gillian Lee Hsieh, Jonathan Michael Howard, Erik Lehnert, Julia Salzman
    bioRxiv 178061; doi: https://doi.org/10.1101/178061
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  • Hydrogen peroxide formation by Nox4 limits malignant transformation
    Valeska Helfinger, Florian Freiherr von Gall, Nina Henke, Michael M. Kunze, Tobias Schmid, Juliana Heidler, Ilka Wittig, Heinfried H. Radeke, Viola Marschall, Karen Anderson, Ajay M. Shah, Simone Fulda, Bernhard Brüne, Ralf P. Brandes, Katrin Schröder
    bioRxiv 177055; doi: https://doi.org/10.1101/177055
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  • Variable dose analysis: A novel RNAi-based method for detection of synthetic lethal interactions
    Benjamin E. Housden, Zhongchi Li, Colleen Kelley, Yuanli Wang, Yanhui Hu, Alexander J. Valvezan, Brendan D. Manning, Norbert Perrimon
    bioRxiv 176974; doi: https://doi.org/10.1101/176974
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  • Recasting the cancer stem cell hypothesis: unification using a continuum model of microenvironmental forces
    Jacob G. Scott, Andrew Dhawan, Anita Hjelmeland, Justin Lathia, Anastasia Chumakova, Masahiro Hitomi, Alexander G. Fletcher, Philip K. Maini, Alexander R. A. Anderson
    bioRxiv 169615; doi: https://doi.org/10.1101/169615
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  • Somatic genome editing with the RCAS/TVA-CRISPR/Cas9 system for precision tumor modeling
    Barbara Oldrini, Álvaro Curiel-García, Carolina Marques, Veronica Matia, Özge Uluçkan, Raul Torres-Ruiz, Sandra Rodriguez-Perales, Jason T. Huse, Massimo Squatrito
    bioRxiv 162669; doi: https://doi.org/10.1101/162669
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  • The evolution of tumour composition during fractionated radiotherapy: implications for outcome
    Thomas D. Lewin, Philip K Maini, Eduardo G Moros, Heiko Enderling, Helen M Byrne
    bioRxiv 175828; doi: https://doi.org/10.1101/175828
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  • Pathway-Level Integration of Proteogenomic Data in Breast Cancer Using Independent Component Analysis
    Wenke Liu, Sisi Ma, David Fenyö
    bioRxiv 175687; doi: https://doi.org/10.1101/175687
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  • Immunologic Effect of Polysaccharides Extracted from Sipunculus nudus (SNP) on Hepatoma HepG2-bearing Mice
    Jie Su, Linlin Jiang, Jingna Wu, Zhiyu Liu, Yuping Wu
    bioRxiv 175190; doi: https://doi.org/10.1101/175190
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  • Nitric oxide-dependent inflammation underlies Notch and PI3K/Akt oncogene cooperation
    Santiago Nahuel Villegas, Rita Gombos, Irene Gutiérrez Pérez, Lucia García López, Jesús García-Castillo, Diana Marcela Vallejos, Vanina Da Ros, József Mihály, Maria Dominguez
    bioRxiv 174169; doi: https://doi.org/10.1101/174169
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  • The DNA methylation landscape of glioblastoma disease progression shows extensive heterogeneity in time and space
    Johanna Klughammer, Barbara Kiesel, Thomas Roetzer, Nikolaus Fortelny, Amelie Kuchler, Nathan C. Sheffield, Paul Datlinger, Nadine Peter, Karl-Heinz Nenning, Julia Furtner, Martha Nowosielski, Marco Augustin, Mario Mischkulnig, Thomas Ströbel, Patrizia Moser, Christian F. Freyschlag, Johannes Kerschbaumer, Claudius Thomé, Astrid E. Grams, Günther Stockhammer, Melitta Kitzwoegerer, Stefan Oberndorfer, Franz Marhold, Serge Weis, Johannes Trenkler, Johanna Buchroithner, Josef Pichler, Johannes Haybaeck, Stefanie Krassnig, Kariem Madhy Ali, Gord von Campe, Franz Payer, Camillo Sherif, Julius Preiser, Thomas Hauser, Peter A. Winkler, Waltraud Kleindienst, Franz Würtz, Tanisa Brandner-Kokalj, Martin Stultschnig, Stefan Schweiger, Karin Dieckmann, Matthias Preusser, Georg Langs, Bernhard Baumann, Engelbert Knosp, Georg Widhalm, Christine Marosi, Johannes A. Hainfellner, Adelheid Woehrer, Christoph Bock
    bioRxiv 173864; doi: https://doi.org/10.1101/173864
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