Cancer Biology

A single-cell multi-omic and spatial atlas of B cell lymphomas reveals differentiation drives intratumor heterogeneity
Donnacha Fitzgerald, Tobias Roider, Marc-Andrea Baertsch, Artur Kibler, Anastasiia Horlova, Erin Chung, Harald Vöhringer, Anna Mathioudaki, Bettina Budeus, Verena Passerini, Mareike Knoll, Johannes Mammen, Linsha Li, Léandra Caillé, Felix Czernilofsky, Peter-Martin Bruch, Nora Liebers, Matthias Meyer-Bender, Oliver Weigert, Judith Zaugg, Garry Nolan, Marc Seifert, Sascha Dietrich, Wolfgang Huber

bioRxiv 2023.11.06.565756; doi: https://doi.org/10.1101/2023.11.06.565756 New Results

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Discovering Novel Prognostic Biomarkers of Hepatocellular Carcinoma using eXplainable Artificial Intelligence
Elizabeth Gutierrez-Chakraborty, Debaditya Chakraborty, Debodipta Das, Yidong Bai

bioRxiv 2023.11.27.568859; doi: https://doi.org/10.1101/2023.11.27.568859 New Results

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Transcriptional immune suppression and upregulation of double stranded DNA damage and repair repertoires in ecDNA-containing tumors
Miin S. Lin, Se-Young Jo, Jens Luebeck, Howard Y. Chang, Sihan Wu, Paul S. Mischel, Vineet Bafna

bioRxiv 2023.04.24.537925; doi: https://doi.org/10.1101/2023.04.24.537925 New Results

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H2A.Z chaperones converge on histone H4 acetylation for melanoma cell proliferation
Sina Jostes, Chiara Vardabasso, Joanna Dong, Saul Carcamo, Rajendra Singh, Robert Phelps, Austin Meadows, Dan Hasson, Emily Bernstein

bioRxiv 2023.11.26.568747; doi: https://doi.org/10.1101/2023.11.26.568747 New Results

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Epigenetic Small-Molecule Screen for Inhibition and Reversal of Acinar Ductal Metaplasia in Mouse Pancreatic Organoids
Kalina R. Atanasova, Corey M. Perkins, Ranjala Ratnayake, Jinmai Jiang, Qi-Yin Chen, Thomas D. Schmittgen, Hendrik Luesch

bioRxiv 2023.11.27.567685; doi: https://doi.org/10.1101/2023.11.27.567685 New Results

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The Myc-Like Mlx Network Impacts Aging and Metabolism
Huabo Wang, Taylor Stevens, Jie Lu, Alexander Roberts, Clinton Van’t Land, Radhika Muzumdar, Zhenwei Gong, Jerry Vockley, Edward V. Prochownik

bioRxiv 2023.11.26.568749; doi: https://doi.org/10.1101/2023.11.26.568749 New Results

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Developing folate-conjugated miR-34a therapeutic for prostate cancer treatment: Challenges and promises
Wen (Jess) Li, Yunfei Wang, Xiaozhuo Liu, Shan Wu, Moyi Wang, Amanda Tracz, Ahmed M. Abdelaal, Kasireddy Sudarshan, Igor Puzanov, Gurkamal Chatta, Andrea L. Kasinski, Dean G. Tang

bioRxiv 2023.11.25.568612; doi: https://doi.org/10.1101/2023.11.25.568612 New Results

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Next-Gen Profiling of Tumor-resident Stem Cells using Machine Learning
Debojyoti Chowdhury, Bhavesh Neekhra, Shreyansh Priyadarshi, Swapnanil Mukherjee, Debashruti Maity, Debayan Gupta, Shubhasis Haldar

bioRxiv 2023.11.24.568600; doi: https://doi.org/10.1101/2023.11.24.568600 New Results

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NF1 deficiency drives metabolic reprogramming in ER+ breast cancer
Rachel (Rae) J House, Elizabeth A. Tovar, Curt J. Essenburg, Patrick S. Dischinger, Abigail E. Ellis, Ian Beddows, Ryan D. Sheldon, Evan C. Lien, Carrie R. Graveel, Matthew R. Steensma

bioRxiv 2023.11.24.568339; doi: https://doi.org/10.1101/2023.11.24.568339 New Results

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Modelling glioblastoma resistance to temozolomide. Combination of spheroid and mathematical models to simulate cellular adaptation in vitro
Marina Pérez-Aliacar, Jacobo Ayensa-Jiménez, Teodora Ranđelović, Ignacio Ochoa, Manuel Doblaré

bioRxiv 2023.11.24.568421; doi: https://doi.org/10.1101/2023.11.24.568421 New Results

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Cancer Biology

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