Cancer Biology

Pathogenic impact of transcript isoform switching in 1209 cancer samples covering 27 cancer types using an isoform-specific interaction network
Abdullah Kahraman, Christian von Mering

bioRxiv 742379; doi: https://doi.org/10.1101/742379 New Results

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The novel reversible LSD1 inhibitor SP-2577 promotes anti-tumor immunity in SWItch/Sucrose-NonFermentable (SWI/SNF) complex mutated ovarian cancer
Raffaella Soldi, Tithi Ghosh Halder, Alexis Weston, Trason Thode, Kevin Drenner, Rhonda Lewis, Mohan R. Kaadige, Shreyesi Srivastava, Sherin Daniel Ampanattu, Ryan Rodriguez del Villar, Jessica Lang, Hariprasad Vankayalapati, Bernard Weissman, Jeffrey M. Trent, William P.D. Hendricks, Sunil Sharma

bioRxiv 2020.01.10.902528; doi: https://doi.org/10.1101/2020.01.10.902528 New Results

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HDAC and MAPK/ERK Inhibitors Cooperate to Reduce Viability and Stemness in Medulloblastoma
Mariane da Cunha Jaeger, Eduarda Chiesa Ghisleni, Paula Schoproni Cardoso, Marialva Siniglaglia, Tiago Falcon, André T. Brunetto, Algemir L. Brunetto, Caroline Brunetto de Farias, Michael D. Taylor, Carolina Nör, Vijay Ramaswamy, Rafael Roesler

bioRxiv 521393; doi: https://doi.org/10.1101/521393 New Results

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Early detection of biomarkers for circulating tumor cells in Bone marrow and Peripheral blood in a fast-progressing gastric cancer model
Prerna Bali, Ivonne Lozano-Pope, Collin Pachow, Marygorret Obonyo

bioRxiv 2020.01.29.925727; doi: https://doi.org/10.1101/2020.01.29.925727 New Results

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TrkB induced metastatic potential of cancer by suppression of BMP mediated tumor inhibitory activity
Min Soo Kim, Wook Jin

bioRxiv 2020.01.29.924324; doi: https://doi.org/10.1101/2020.01.29.924324 New Results

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Autophagy-mediated degradation of Fatty Acid Synthase (FASN) facilitates ATRA-induced granulocytic differentiation of acute myeloid leukemia (AML) cells
Magali Humbert, Kristina Seiler, Severin Mosimann, Vreni Rentsch, Sharon L. McKenna, Mario P. Tschan

bioRxiv 2020.01.29.924555; doi: https://doi.org/10.1101/2020.01.29.924555 New Results

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Cyclin E1 protein is stabilized in BRCA1 mutated breast cancers leading to synergy between CDK2 and PARP inhibitors
Diar Aziz, Neil Portman, Kristine J. Fernandez, Christine Lee, Sarah Alexandrou, Alba Llop-Guevara, Aliza Yong, Ashleigh Wilkinson, C. Marcelo Sergio, Danielle Ferraro, Dariush Etemadmoghadam, David Bowtell, kConFab Investigators, Violeta Serra, Paul Waring, Elgene Lim, C. Elizabeth Caldon

bioRxiv 2020.01.29.911883; doi: https://doi.org/10.1101/2020.01.29.911883 New Results

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Landscape of transcript isoforms in single T cells infiltrating in non-small cell lung cancer
Jiesheng Li, Zemin Zhang, Xianwen Ren

bioRxiv 2020.01.29.924308; doi: https://doi.org/10.1101/2020.01.29.924308 New Results

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Pervasive promoter hypermethylation of silenced TERT alleles in human cancers
D Esopi, MK Graham, J Brosnan-Cashman, J Meyers, A Vaghasia, A Gupta, B Kumar, MC Haffner, CM Heaphy, AM De Marzo, AK Meeker, WG Nelson, SJ Wheelan, S Yegnasubramanian

bioRxiv 2020.01.29.925552; doi: https://doi.org/10.1101/2020.01.29.925552 New Results

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Obesity-driven changes in ECM composition promote local invasion and metastasis of breast tumors
Andrew Wishart, Yifan Peng, Sydney Conner, Justinne Guarin, Rebecca Crews, Jackson Fatherree, Andrew S. Greenberg, Madeleine J. Oudin

bioRxiv 2020.01.29.924431; doi: https://doi.org/10.1101/2020.01.29.924431 New Results

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Cancer Biology

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