Cancer Biology

Werner syndrome helicase is a selective vulnerability of microsatellite instability high tumor cells
Simone Lieb, Silvia Blaha-Ostermann, Elisabeth Kamper, Katharina Ehrenhoefer-Woelfer, Andreas Schlattl, Andreas Wernitznig, Jesse J Lipp, Kota Nagasaka, Gerd Bader, Ralph A Neumueller, Norbert Kraut, Mark A Pearson, Mark Petronczki, Simon Woehrle

bioRxiv 530659; doi: https://doi.org/10.1101/530659 New Results
ADAMDEC1 maintains a novel growth factor signaling loop in cancer stem cells
James S Hale, Ana Jimenez-Pascual, Anja Kordowski, Jamie Pugh, Shilpa Rao, Daniel J Silver, Tyler Alban, Defne Bayik Watson, Rui Chen, Thomas M McIntyre, Giorgio Colombo, Guilia Taraboletti, Karl O Holmberg, Karin Forsberg-Nilsson, Justin D Lathia, Florian Siebzehnrubl

bioRxiv 531509; doi: https://doi.org/10.1101/531509 New Results
Identification of frequent activating HER2 mutations in primary canine pulmonary adenocarcinoma
Gwendolen Lorch, Karthigayini Sivaprakasam, Victoria Zismann, Nieves Perdigones, Tania Contente-Cuomo, Alexandra Nazareno, Salvatore Facista, Shukmei Wong, Winnie S. Liang, Joseph M. Amann, Sara L. Sinicropi-Yao, Michael J. Koenig, Krista La Perle, Timothy G. Whitsett, Muhammed Murtaza, Jeffrey Trent, David P. Carbone, William P.D. Hendricks

bioRxiv 528182; doi: https://doi.org/10.1101/528182 New Results
Adaption of artificial microvascular networks
Thierry Fredrich, Michael Welter, Heiko Rieger

bioRxiv 429027; doi: https://doi.org/10.1101/429027 Contradictory Results
Beyond synthetic lethality: charting the landscape of clinically relevant genetic interactions in cancer
Assaf Magen, Avinash Das, Joo Sang Lee, Mahfuza Sharmin, Alexander Lugo, J. Silvio Gutkind, Alejandro A. Schaffer, Eytan Ruppin, Sridhar Hannenhalli

bioRxiv 253120; doi: https://doi.org/10.1101/253120 New Results
Endogenous insulin contributes to pancreatic cancer development
Anni MY Zhang, Jamie Magrill, Twan J.J. de Winter, Xiaoke Hu, Sos Skovso, David F Schaeffer, Janel L Kopp, James D Johnson

bioRxiv 530097; doi: https://doi.org/10.1101/530097 New Results
On measuring selection in cancer from subclonal mutation frequencies
Ivana Bozic, Chay Paterson, Bartlomiej Waclaw

bioRxiv 529396; doi: https://doi.org/10.1101/529396 New Results
C-terminal HSP90 Inhibitors Block the HSP90:HIF-1a Interaction and Inhibit the Cellular Hypoxic Response
Nalin Kataria, Bernadette Kerr, Samantha Zaiter, Shelli R McAlpine, Kristina M Cook

bioRxiv 521989; doi: https://doi.org/10.1101/521989 New Results
RBL1 (p107) functions as tumor suppressor in glioblastoma and small-cell pancreatic neuroendocrine carcinoma
Thomas Naert, Dionysia Dimitrakopoulou, Dieter Tulkens, Suzan Demuynck, Rivka Noelanders, Liza Eeckhout, Gert Van Isterdael, Dieter Deforce, Christian Vanhove, Jo Van Dorpe, David Creytens, Kris Vleminckx

bioRxiv 528299; doi: https://doi.org/10.1101/528299 New Results
The Evolution of Placental Invasion and Cancer Metastasis are Causally Linked
Kshitiz Gupta, Junaid Afzal, Jamie D. Maziarz, Archer Hamidzadeh, Cong Liang, Eric M. Erkenbrack, Hong Nam, Jan-Dirk Haeger, Christiane Pfarrer, Thomas Hoang, Troy Ott, Thomas Spencer, Mihaela Pavlicev, Doug Antczak, Andre Levchenko, Gunter P. Wagner

bioRxiv 528646; doi: https://doi.org/10.1101/528646 New Results

Cancer Biology

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