Cancer Biology

Chromosome 1q amplification perturbs a ceRNA network to promote melanoma metastasis
Xiaonan Xu, Kaizhen Wang, Olga Vera, Akanksha Verma, Olivier Elemento, Xiaoqing Yu, Florian A. Karreth

bioRxiv 2021.11.14.468531; doi: https://doi.org/10.1101/2021.11.14.468531 New Results

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Microfluidic system-based time-course tracking of physical proximity between cells and its effect on gene expression for elucidating live single cancer-immune cell interactions
Bianca C. T. Flores, Smriti Chawla, Ning Ma, Chad Sanada, Praveen Kumar Kujur, Ludmilla T. D. Chinen, Kyle Hukari, Mark Lynch, Naveen Ramalingam, Debarka Sengupta, Stefanie S. Jeffrey

bioRxiv 2021.11.13.468447; doi: https://doi.org/10.1101/2021.11.13.468447 New Results

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Identifying common transcriptome signatures of cancer by interpreting deep learning models
Anupama Jha, Mathieu Quesnel-Vallières, Andrei Thomas-Tikhonenko, Kristen W. Lynch, Yoseph Barash

bioRxiv 2021.11.11.467790; doi: https://doi.org/10.1101/2021.11.11.467790 New Results

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G6PD deficiency sensitizes metastasizing melanoma cells to oxidative stress and glutaminolysis
Arin B. Aurora, Vishal Khivansara, Ashley Leach, Jennifer G. Gill, Misty Martin-Sandoval, Chendong Yang, Stacy Y. Kasitinon, Divya Bezwada, Alpaslan Tasdogan, Wen Gu, Thomas Mathews, Zhiyu Zhao, Ralph J. DeBerardinis, Sean J. Morrison

bioRxiv 2021.11.11.468286; doi: https://doi.org/10.1101/2021.11.11.468286 New Results

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An instance-specific causal framework for learning intercellular communication networks that define microenvironments of individual tumors
Xueer Chen, Lujia Chen, Cornelius H.L. Kürten, Fattaneh Jabbari, Lazar Vujanovic, Ying Ding, Aditi Kulkarni, Tracy Tabib, Robert Lafyatis, Gregory Cooper, Robert Ferris, Xinghua Lu

bioRxiv 2021.11.11.467838; doi: https://doi.org/10.1101/2021.11.11.467838 New Results

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Vitamin D deficiency increases prostatic megalin expression and globulin-bound testosterone import, increasing prostatic androgens in African American men
Jason Garcia, Kirstin D. Krieger, Candice Loitz, Lillian Perez, Zachary A. Richards, Yves Helou, Steve Kregel, Clementina A. Mesaros, Peter H. Gann, Donald Vander Griend, Rick Kittles, Gail S. Prins, Trevor Penning, Larisa Nonn

bioRxiv 2021.11.09.467567; doi: https://doi.org/10.1101/2021.11.09.467567 New Results

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RPRM negatively regulates ATM levels involving its phosphorylation mediated by CDK4/CDK6
Yarui Zhang, Guomin Ou, Zhujing Ye, Zhou Zhou, Qianlin Cao, Mengting Li, Jingdong Wang, Jianping Cao, Hongying Yang

bioRxiv 2021.11.10.468148; doi: https://doi.org/10.1101/2021.11.10.468148 New Results

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EBV LMP1-activated mTORC1 and mTORC2 Coordinately Promote Nasopharyngeal Cancer Stem Cell Formation
Nannan Zhu, Qian Wang, Zhidong Wu, Yan Wang, Mu-Sheng Zeng, Yan Yuan

bioRxiv 2021.11.10.468172; doi: https://doi.org/10.1101/2021.11.10.468172 New Results

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The hexokinase “HKDC1” interaction with the mitochondria is essential for hepatocellular carcinoma progression
Md. Wasim Khan, Alexander R. Terry, Medha Priyadarshini, Grace Guzman, Jose Cordoba-Chacon, Issam Ben-Sahra, Barton Wicksteed, Brian T. Layden

bioRxiv 2021.11.10.468146; doi: https://doi.org/10.1101/2021.11.10.468146 New Results

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PTP1B is an intracellular checkpoint that limits T cell and CAR T cell anti-tumor immunity
Florian Wiede, Kun-Hui Lu, Xin Du, Mara N. Zeissig, Rachel Xu, Pei Kee Goh, Chrysovalantou E. Xirouchaki, Samuel J. Hogarth, Spencer Greatorex, Kevin Sek, Roger J. Daly, Paul A. Beavis, Phillip K. Darcy, Nicholas K. Tonks, Tony Tiganis

bioRxiv 2021.11.11.468140; doi: https://doi.org/10.1101/2021.11.11.468140 New Results

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Cancer Biology

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