Cancer Biology

Proteomic characterisation of Sarculator nomogram-defined risk groups in soft tissue sarcomas of the extremities and trunk wall
Madhumeeta Chadha, Sara Iadecola, Andrew Jenks, Jessica Burns, Amani Arthur, Valeriya Pankova, Christopher P Wilding, Dario Callegaro, Dirk C Strauss, Khin Thway, Alessandro Gronchi, Robin L Jones, Rosalba Miceli, Sandro Pasquali, Paul H Huang

bioRxiv 2023.11.14.567122; doi: https://doi.org/10.1101/2023.11.14.567122 New Results

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TIPE drives a cancer stem-like phenotype by promoting glycolysis via PKM2/HIF-1α axis in melanoma
Maojin Tian, Le Yang, Ziqian Zhao, Jigang Li, Lianqing Wang, Qingqing Yin, Wei Hu, Yunwei Lou, Jianxin Du, Peiqing Zhao

bioRxiv 2023.11.14.567124; doi: https://doi.org/10.1101/2023.11.14.567124 New Results

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Epigenetic heritability of cell plasticity drives cancer drug resistance through one-to-many genotype to phenotype mapping
Javier Fernandez-Mateos, Salvatore Milite, Erica Oliveira, Georgios Vlachogiannis, Bingjie Chen, Erika Yara, George D Cresswell, Chela James, Lucrezia Patruno, Gianluca Ascolani, Ahmet Acar, Timon Heide, Inma Spiteri, Alex Graudenzi, Giulio Caravagna, Trevor Graham, Luca Magnani, Nicola Valeri, Andrea Sottoriva

bioRxiv 2023.11.15.567140; doi: https://doi.org/10.1101/2023.11.15.567140 New Results

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ADGRE5 ACTS AS A MELANOMA TUMOR SUPPRESSOR IN NATURALLY HYBRIDIZING XIPHOPHORUS
Mateo Garcia-Olazabal, Mateus Contar Adolfi, Brigitta Wilde, Anita Hufnagel, Rupesh Paudel, Yuan Lu, Svenja Meierjohann, Gil Rosenthal, Manfred Schartl

bioRxiv 2023.11.14.567049; doi: https://doi.org/10.1101/2023.11.14.567049 New Results

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Telomerase reverse transcriptase induces targetable alterations in glutathione and nucleotide biosynthesis in glioblastomas
Suresh Udutha, Céline Taglang, Georgios Batsios, Anne Marie Gillespie, Meryssa Tran, Sabrina M Ronen, Johanna ten Hoeve, Thomas G Graeber, Pavithra Viswanath

bioRxiv 2023.11.14.566937; doi: https://doi.org/10.1101/2023.11.14.566937 New Results

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Tumor cell-derived spermidine promotes a pro-tumorigenic immune microenvironment in glioblastoma via CD8+ T cell inhibition
Kristen E. Kay, Juyeun Lee, Ellen S. Hong, Julia Beilis, Sahil Dayal, Emily Wesley, Sofia Mitchell, Sabrina Z. Wang, Daniel J. Silver, Josephine Volovetz, Sadie Johnson, Mary McGraw, Matthew M. Grabowski, Tianyao Lu, Lutz Freytag, Vinod Narayana, Saskia Freytag, Sarah A. Best, James R. Whittle, Zeneng Wang, Ofer Reizes, Jennifer S. Yu, Stanley L. Hazen, J. Mark Brown, Defne Bayik, Justin D. Lathia

bioRxiv 2023.11.14.567048; doi: https://doi.org/10.1101/2023.11.14.567048 New Results

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PI3Kδ activation, IL6 over-expression, and CD37 loss cause resistance to the targeting of CD37-positive lymphomas with the antibody-drug conjugate naratuximab emtansine
Alberto J. Arribas, Eugenio Gaudio, Sara Napoli, Charles Jean Yvon Herbaux, Chiara Tarantelli, Roberta Pittau Bordone, Luciano Cascione, Nicolas Munz, Luca Aresu, Jacopo Sgrignani, Andrea Rinaldi, Ivo Kwee, Davide Rossi, Andrea Cavalli, Emanuele Zucca, Georg Stussi, Anastasios Stathis, Callum Sloss, Matthew S. Davids, Francesco Bertoni

bioRxiv 2023.11.14.566994; doi: https://doi.org/10.1101/2023.11.14.566994 New Results

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Immunotherapy for ovarian cancer is improved by tumor targeted delivery of a neoantigen surrogate
Lauren Rose Scanlon, Lisa Gabor, Olivia Khouri, Shahbaz Ahmad, Evan Levy, Dennis Yi-Shin Kuo, Ken Lin, Nicole Nevadunsky, Sara Isani, Claudia Gravekamp

bioRxiv 2023.10.11.561944; doi: https://doi.org/10.1101/2023.10.11.561944 New Results

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Unravelling the metastasis-preventing effect of miR-200c in vitro and in vivo
Bianca Köhler, Emily Brieger, Tom Brandstätter, Elisa Hörterer, Ulrich Wilk, Jana Pöhmerer, Anna Jötten, Philipp Paulitschke, Chase P Broedersz, Stefan Zahler, Joachim O Rädler, Ernst Wagner, Andreas Roidl

bioRxiv 2023.11.14.566527; doi: https://doi.org/10.1101/2023.11.14.566527 New Results

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SANTA FE OXA: Self-assembled oxaliplatin nanomicelle for enhanced cascade cancer chemotherapy via self-sensitized ferroptosis
Jianbin Shi, Wenjing Ma, Shunzhe Zheng, Fengli Xia, Xinying Liu, Ayumi Kikkawa, Kaho Tanaka, Ken-ichiro Kamei, Chutong Tian

bioRxiv 2023.11.13.566938; doi: https://doi.org/10.1101/2023.11.13.566938 New Results

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Cancer Biology

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