Cancer Biology

The Evolutionary Landscape of Pan-Cancer Drives Clinical Aggression
Shichao Pang, Leilei Wu, Xin Shen, Yidi Sun, Jingfang Wang, Yi-Lei Zhao, Zhen Wang, Yixue Li

bioRxiv 422667; doi: https://doi.org/10.1101/422667 New Results
Molecular measurable residual disease testing of blood during AML cytotoxic therapy for early prediction of clinical response
Hong Yuen Wong, Anthony D Sung, Katherine E Lindblad, Sheenu Sheela, Gregory W Roloff, David Rizzieri, Meghali Goswami, Matthew P Mule, Nestor R Ramos, Jingrong Tang, Julie Thompson, Christin B DeStefano, Kristi Romero, Laura W Dillon, Dong-Yun Kim, Catherine Lai, Christopher S Hourigan

bioRxiv 422352; doi: https://doi.org/10.1101/422352 New Results
Selective inhibition of CA IX over CA XII using benzene sulfonamides in breast cancer cells: Disconnect between CA activity and growth inhibition
Mam Y Mboge, Zhijuan Chen, Alyssa Wolff, John V Mathias, Chingkuang Tu, Kevin D Brown, Murat Bozdag, Fabrizio Carta, Claudiu T Supuran, Robert McKenna, Susan C Frost

bioRxiv 345298; doi: https://doi.org/10.1101/345298 New Results
Prostaglandin F2α-induced TGFβ-PMEPA1 pathway is a critical mediator of epithelial plasticity and ovarian carcinoma progression.
Alba Jimenez-Segovia, Alba Mota, Alejandro Rojo-Sebastian, Beatriz Barrocal, Angela Rynne-Vidal, Maria Laura Garcia-Bermejo, Raquel Gomez-Bris, Lukas J.A.C. Hawinkels, Pilar Sandoval, Ramon Garcia-Escudero, Manuel Lopez-Cabrera, Gema Moreno-Bueno, Manuel Fresno, Konstantinos Stamatakis

bioRxiv 418582; doi: https://doi.org/10.1101/418582 New Results
Dihydropyrimidinase protects from DNA replication stress caused by cytotoxic metabolites.
Jihane Basbous, Antoine Aze, Laurent Chaloin, Rana Lebdy, Dana Hodroj, Cyril Ribeyre, Marion Larroque, Caitlin Shepard, Baek Kim, Alain Pruvost, Jerome Moreaux, Domenico Maiorano, Marcel Mechali, Angelos Constantinou

bioRxiv 420893; doi: https://doi.org/10.1101/420893 New Results
High-dimensional single cell-analysis of lymphocytic activation in melanoma
Francesca Maria Bosisio, Asier Antoranz, Maddalena Maria Bolognesi, Clizia Chinello, Jasper Wouters, Fluvio Magni, Leonidas Alexopoulos, Giorgio Cattoretti, Joost van den Oord

bioRxiv 409011; doi: https://doi.org/10.1101/409011 New Results
Non-driver somatic alteration burden confers good prognosis in non-small cell lung cancer
Dennis Wang, Nhu-An Pham, Timothy M Freeman, Vibha Raghavan, Roya Navab, Elena Pasko, Jonathan Chang, Chang-Qi Zhu, Dalam Ly, Jiefei Tong, Bradly G Wouters, Melania Pintilie, Michael F Moran, Frances A Shepherd, Ming-Sound Tsao

bioRxiv 419424; doi: https://doi.org/10.1101/419424 New Results
A second generation IL-2 receptor-targeted diphtheria fusion toxin exhibits anti-tumor activity and synergy with anti-PD-1 in melanoma
Laurene S. Cheung, Juan Fu, Pankaj Kumar, Amit Kumar, Michael E. Urbanowski, Elizabeth A. Ihms, Sadiya Parveen, C. Korin Bullen, Garrett Patrick, Robert Harrison, John R. Murphy, Drew M. Pardoll, William Bishai

bioRxiv 420158; doi: https://doi.org/10.1101/420158 New Results
Optimization of Dose Schedules for Chemotherapy of Early Colon Cancer Determined by High Performance Computer Simulations
Chase Cockrell, David Axelrod

bioRxiv 420232; doi: https://doi.org/10.1101/420232 New Results
The Inter and Intra-Tumoural Heterogeneity of Subclonal Reconstruction
Vinayak Bhandari, Lydia Y Liu, Adriana Salcedo, Shadrielle MG Espiritu, Quaid D Morris, Paul C Boutros

bioRxiv 418780; doi: https://doi.org/10.1101/418780 New Results

Cancer Biology

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