Clinical Trials

Functional connectivity changes with rapid remission from severe major depressive disorder
Xiaoqian Xiao, Brandon S. Bentzley, Eleanor J. Cole, Claudia Tischler, Katy H. Stimpson, Dalton Duvio, James H. Bishop, Danielle D. DeSouza, Alan Schatzberg, Corey Keller, Keith D. Sudheimer, Nolan R. Williams

bioRxiv 672154; doi: https://doi.org/10.1101/672154 New Results

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Identifying Severe Stroke Patients Likely to Benefit From Thrombectomy Despite Delays of up to a Day
R. Gilberto González, Gisele Sampaio Silva, Julian He, Saloomeh Sadaghiani, Ona Wu, Aneesh B. Singhal

bioRxiv 526947; doi: https://doi.org/10.1101/526947 New Results

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FDAAA TrialsTracker: A live informatics tool to monitor compliance with FDA requirements to report clinical trial results
Nicholas J. DeVito, Seb Bacon, Ben Goldacre

bioRxiv 266452; doi: https://doi.org/10.1101/266452 New Results

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Effects of daily L-dopa administration on learning and brain structure in older adults undergoing cognitive training: a randomised clinical trial
Alexander V. Lebedev, Jonna Nilsson, Joanna Lindström, William Fredborg, Ulrika Akenine, Carolina Hillilä, Pia Andersen, Gabriela Spulber, Elizabeth CM de Lange, Dirk-Jan van den Berg, Miia Kivipelto, Martin Lövdén

bioRxiv 482679; doi: https://doi.org/10.1101/482679 New Results

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Stanford Accelerated Intelligent Neuromodulation Therapy for Treatment-Resistant Depression (SAINT-TRD)
Eleanor J. Cole, Katy H. Stimpson, Brandon S. Bentzley, Merve Gulser, Kirsten Cherian, Claudia Tischler, Romina Nejad, Heather Pankow, Elizabeth Choi, Haley Aaron, Flint M. Espil, Jaspreet Pannu, Xiaoqian Xiao, Dalton Duvio, Hugh B. Solvason, Jessica Hawkins, Austin Guerra, Booil Jo, Kristin S. Raj, Charles Debattista, Jennifer Keller, Alan F. Schatzberg, Keith D. Sudheimer, Nolan R. Williams

bioRxiv 581280; doi: https://doi.org/10.1101/581280 New Results

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Fecal microbiota transplantation brings about bacterial strain displacement in patients with inflammatory bowel diseases
Manli Zou, Zhuye Jie, Bota Cui, Honggang Wang, Qiang Feng, Yuanqiang Zou, Xiuqing Zhang, Huanming Yang, Jian Wang, Faming Zhang, Huijue Jia

bioRxiv 439687; doi: https://doi.org/10.1101/439687 New Results

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Nicotinamide riboside augments the human skeletal muscle NAD⁺ metabolome and induces transcriptomic and anti-inflammatory signatures in aged subjects: a placebo-controlled, randomized trial
Yasir S Elhassan, Katarina Kluckova, Rachel S Fletcher, Mark Schmidt, Antje Garten, Craig L Doig, David M Cartwright, Lucy Oakey, Claire V Burley, Ned Jenkinson, Martin Wilson, Samuel J E Lucas, Ildem Akerman, Alex Seabright, Yu-Chiang Lai, Daniel A Tennant, Peter Nightingale, Gareth A Wallis, Konstantinos N Manolopoulos, Charles Brenner, Andrew Philp, Gareth G Lavery

bioRxiv 680462; doi: https://doi.org/10.1101/680462

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Efficacy and safety of a novel vaginal medical device in recurrent bacterial vaginosis: an international multicentre clinical trial
Filippo Murina, Ciprian Crişan, Marius Biriş, Daniela Sîrbu, Dionisio Franco Barattini, Luca Ivan Ardolino, Elena Casolati

bioRxiv 674705; doi: https://doi.org/10.1101/674705

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Targeting the Autonomic Nervous System Balance in Patients with Chronic Low Back Pain using Transcranial Alternating Current Stimulation: A Randomized, Crossover, Double-Blind, Placebo-Controlled Pilot Study
Julianna H. Prim, Sangtae Ahn, Maria I. Davila, Morgan L. Alexander, Karen L. McCulloch, Flavio Fröhlich

bioRxiv 668541; doi: https://doi.org/10.1101/668541

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PARP1 as a biomarker for early detection and intraoperative tumor delineation in epithelial cancers – first-in-human results
Susanne Kossatz, Giacomo Pirovano, Paula Demétrio De Souza França, Arianna L. Strome, Sumsum P. Sunny, Daniella Karassawa Zanoni, Audrey Mauguen, Brandon Carney, Christian Brand, Veer Shah, Ravindra D. Ramanajinappa, Naveen Hedne, Praveen Birur, Smita Sihag, Ronald A. Ghossein, Mithat Gönen, Marshall Strome, Amritha Suresh, Daniela Molena, Moni A. Kuriakose, Snehal G. Patel, Thomas Reiner

bioRxiv 663385; doi: https://doi.org/10.1101/663385

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Clinical Trials

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