Clinical Trials

Nicotinamide riboside augments the human skeletal muscle NAD⁺ metabolome and induces transcriptomic and anti-inflammatory signatures in aged subjects: a placebo-controlled, randomized trial
Yasir S Elhassan, Katarina Kluckova, Rachel S Fletcher, Mark Schmidt, Antje Garten, Craig L Doig, David M Cartwright, Lucy Oakey, Claire V Burley, Ned Jenkinson, Martin Wilson, Samuel J E Lucas, Ildem Akerman, Alex Seabright, Yu-Chiang Lai, Daniel A Tennant, Peter Nightingale, Gareth A Wallis, Konstantinos N Manolopoulos, Charles Brenner, Andrew Philp, Gareth G Lavery

bioRxiv 680462; doi: https://doi.org/10.1101/680462 New Results

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Efficacy and safety of a novel vaginal medical device in recurrent bacterial vaginosis: an international multicentre clinical trial
Filippo Murina, Ciprian Crişan, Marius Biriş, Daniela Sîrbu, Dionisio Franco Barattini, Luca Ivan Ardolino, Elena Casolati

bioRxiv 674705; doi: https://doi.org/10.1101/674705 New Results

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Stanford Accelerated Intelligent Neuromodulation Therapy (SAINT) Induces Functional Connectivity Changes in Emotion Regulation Brain Areas for MDD Patients
Xiaoqian Xiao, Brandon S. Bentzley, Eleanor Cole, Claudia Tischler, Katy H. Stimpson, Dalton Duvio, James Bishop, Alan Schatzberg, Corey Keller, Keith Sudheimer, Nolan R. Williams

bioRxiv 672154; doi: https://doi.org/10.1101/672154 New Results

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Targeting the Autonomic Nervous System Balance in Patients with Chronic Low Back Pain using Transcranial Alternating Current Stimulation: A Randomized, Crossover, Double-Blind, Placebo-Controlled Pilot Study
Julianna H. Prim, Sangtae Ahn, Maria I. Davila, Morgan L. Alexander, Karen L. McCulloch, Flavio Fröhlich

bioRxiv 668541; doi: https://doi.org/10.1101/668541 New Results

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PARP1 as a biomarker for early detection and intraoperative tumor delineation in epithelial cancers – first-in-human results
Susanne Kossatz, Giacomo Pirovano, Paula Demétrio De Souza França, Arianna L. Strome, Sumsum P. Sunny, Daniella Karassawa Zanoni, Audrey Mauguen, Brandon Carney, Christian Brand, Veer Shah, Ravindra D. Ramanajinappa, Naveen Hedne, Praveen Birur, Smita Sihag, Ronald A. Ghossein, Mithat Gönen, Marshall Strome, Amritha Suresh, Daniela Molena, Moni A. Kuriakose, Snehal G. Patel, Thomas Reiner

bioRxiv 663385; doi: https://doi.org/10.1101/663385 New Results

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Neurocognitive mechanisms of d-cycloserine augmented single-session exposure therapy for anxiety
Andrea Reinecke, Alecia Nickless, Michael Browning, Catherine J. Harmer

bioRxiv 615757; doi: https://doi.org/10.1101/615757

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Metronomic capecitabine as an immune modulator in glioblastoma patients reduces myeloid-derived suppressor cells
David M. Peereboom, Tyler J. Alban, Matthew M. Grabowski, Alvaro G. Alvarado, Balint Otvos, Defne Bayik, Gustavo Roversi, Mary McGraw, Pengjing Huang, Alireza M. Mohammadi, Harley I. Kornblum, Manmeet S. Ahluwalia, Michael A. Vogelbaum, Justin D. Lathia

bioRxiv 655688; doi: https://doi.org/10.1101/655688

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Restored tactile sensation improves neuroprosthetic arm control
Sharlene N Flesher, John E Downey, Jeffrey M Weiss, Christopher L Hughes, Angelica J Herrera, Elizabeth C Tyler-Kabara, Michael L Boninger, Jennifer L Collinger, Robert A Gaunt

bioRxiv 653428; doi: https://doi.org/10.1101/653428

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Integrated meditation and exercise therapy: A randomized controlled trial of a combined non-pharmacological intervention reduces disability and pain in patients with chronic low back pain
Anna M. Polaski, Amy L. Phelps, Thomas J. Smith, Eric R. Helm, Natalia E. Morone, Kimberly A. Szucs, Matthew C. Kostek, Benedict J. Kolber

bioRxiv 652735; doi: https://doi.org/10.1101/652735

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11β-Hydroxysteroid Dehydrogenase Type 1 inhibition in Idiopathic Intracranial Hypertension: a double-blind randomized controlled trial
Keira Markey, James Mitchell, Hannah Botfield, Ryan S Ottridge, Tim Matthews, Anita Krishnan, Rebecca Woolley, Connar Westgate, Andreas Yiangou, Pushkar Shah, Caroline Rick, Natalie Ives, Angela E Taylor, Lorna C Gilligan, Carl Jenkinson, Wiebke Arlt, William Scotton, Rebecca Fairclough, Rishi Singhal, Paul M Stewart, Jeremy W Tomlinson, Gareth G Lavery, Susan P Mollan, Alexandra J Sinclair

bioRxiv 648410; doi: https://doi.org/10.1101/648410 New Results

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Clinical Trials

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