Clinical Trials

Rapid Whole Genome Sequencing Decreases Morbidity and Healthcare Cost of Hospitalized Infants
Lauge Farnaes, Amber Hildreth, Nathaly Sweeney, Michelle Clark, Shimul Chowdhury, Shareef Nahas, Julie Cakici, Wendy Benson, Robert Kaplan, Richard Kronick, Matthew Bainbridge, Jennifer Friedman, Jeffrey Gold, Yan Ding, Narayanan Veeraraghavan, David Dimmock, Stephen kingsmore, RCIGM Investigators

bioRxiv 253534; doi: https://doi.org/10.1101/253534 New Results
Evaluating a sepsis prediction machine learning algorithm in the emergency department and intensive care unit: a before and after comparative study
Hoyt Burdick, Eduardo Pino, Denise Gabel-Comeau, Carol Gu, Heidi Huang, Anna Lynn-Palevsky, Ritankar Das

bioRxiv 224014; doi: https://doi.org/10.1101/224014 New Results
Correction of the Framingham Risk Score Data Reported in SPRINT
Frederick Warner, Sanket S. Dhruva, Joseph S. Ross, Pranammya Dey, Karthik Murugiah, Harlan M. Krumholz

bioRxiv 235358; doi: https://doi.org/10.1101/235358 Contradictory Results
Similar clinical improvement and maintenance after rTMS at 5 Hz using a simple vs. complex protocol in Alzheimer's disease
Ruth Alcala, Erik Daniel Morelos-Santana, Jose Francisco Cortes-Sotres, Eduardo A Garza-Villarreal, Ana Luisa Sosa, Jorge Julio Gonzalez-Olvera

bioRxiv 232546; doi: https://doi.org/10.1101/232546 New Results
TORC1 inhibition as an immunotherapy to reduce infections in the elderly
Joan B Mannick, Melody Morris, Hans-Ulrich P Hockey, Guglielmo Roma, Martin Beibel, Kenneth Kulmatycki, Mollie Watkins, Tea Shavlakadze, Weihua Zhou, Dean Quinn, David J. Glass, Lloyd B. Klickstein

bioRxiv 230813; doi: https://doi.org/10.1101/230813 New Results
Targeting regulatory T cells with Interleukin-2 treatment in type 1 diabetes: a response-adaptive, non-randomised, open-label trial of repeat doses of Aldesleukin (DILfrequency)
Eleonora Seelig, James Howlett, Linsey Porter, Lucy Truman, James Heywood, Jane Kennet, Emma L Arbon, Katerina Anselmiova, Neil M Walker, Ravinder Atkar, Marcin L Pekaiski, Ed Rytina, Mark Evans, Linda S Wicker, John A Todd, Adrian P Mander, Simon Bond, Frank Waldron-Lynch

bioRxiv 223958; doi: https://doi.org/10.1101/223958 New Results
Effect of vitamin D supplementation on biomarkers of inflammation and immune function: functional genomics analysis of the BEST-D trial
Antonio J Berlanga-Taylor, Katherine Plant, Evelyn Lau, Andrew Dahl, Michael Hill, David Sims, Andreas Heger, Jonathan Emberson, Jane Armitage, Robert Clarke, Julian Knight

bioRxiv 217612; doi: https://doi.org/10.1101/217612 New Results
Influence of APOA5 locus on the treatment efficacy of three statins: evidence from a randomized pilot study in Chinese subjects
Sha Hua, Chuanxiang Ma, Jun Zhang, Jing Li, Weiwei Wu, Ning Xu, Guanghua Luo, Jianrong Zhao

bioRxiv 213629; doi: https://doi.org/10.1101/213629 New Results
The NSIGHT1 Randomized Controlled Trial: Rapid Whole Genome Sequencing for Accelerated Etiologic Diagnosis in Critically Ill Infants
Josh E Petrikin, Julie A Cakici, Michelle Clark, Laurel Willig, Nathaly Sweeney, Emily Farrow, Carol Saunders, Isabelle Thiffault, Neil Miller, Lee Zellmer, Suzanne Herd, Anne Holmes, Serge Batalov, Narayanana Veeraraghavan, Laurie Smith, David Dimmock, Steven Leeder, Stephen F Kingsmore

bioRxiv 218255; doi: https://doi.org/10.1101/218255 New Results
A Pilot Randomized Trial of Oral Magnesium Supplementation on Supraventricular Arrhythmias
Pamela L. Lutsey, Lin Y. Chen, Anne Eaton, Melanie Jaeb, Kyle D. Rudser, James D. Neaton, Alvaro Alonso

bioRxiv 215319; doi: https://doi.org/10.1101/215319 New Results

Clinical Trials

Pages