Genetics

Somatic evolution of cancer genes in sex chromosomes
Antonio Marco, Amarachi C Akachukwu, Jasmine Samantha Ratcliff

bioRxiv 2024.09.11.612525; doi: https://doi.org/10.1101/2024.09.11.612525 New Results

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Stabilising selection enriches the tails of complex traits with rare alleles of large effect
Anil PS Ori, Carla Giner-Delgado, Clive Julian Hoggart, Paul F O'Reilly

bioRxiv 2024.09.12.612687; doi: https://doi.org/10.1101/2024.09.12.612687 New Results

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Genetic regulation of microRNAs in the older adult brain and their contribution to neuropsychiatric conditions
Selina M Vattathil, Ekaterina S Gerasimov, Se Min Canon, Adriana Lori, Sarah Sze Min Tan, Paul J Kim, Yue Liu, Eric C Lai, David A C. Bennett, Thomas S Wingo, Aliza P Wingo

bioRxiv 2024.09.10.610174; doi: https://doi.org/10.1101/2024.09.10.610174 New Results

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Genetic suppression interactions are highly conserved across genetic backgrounds
Claire Paltenghi, Jolanda van Leeuwen

bioRxiv 2024.08.28.610086; doi: https://doi.org/10.1101/2024.08.28.610086 New Results

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Heterosis across an environmental and genetic space
Gabrielle D Sandstedt, Catherine A Rushworth

bioRxiv 2024.09.06.611759; doi: https://doi.org/10.1101/2024.09.06.611759 New Results

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JointPRS: A Data-Adaptive Framework for Multi-Population Genetic Risk Prediction Incorporating Genetic Correlation
Leqi Xu, Geyu Zhou, Wei Jiang, Haoyu Zhang, Yikai Dong, Leying Guan, Hongyu Zhao

bioRxiv 2023.10.29.564615; doi: https://doi.org/10.1101/2023.10.29.564615 New Results

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Stochasticity in dietary restriction-mediated lifespan outcomes in Drosophila
Olivia L Mosley, Joel A Villa, Advaitha Kamalakkannan, Eliyashaib James, Jessica M Hoffman, Yang Lyu

bioRxiv 2024.09.06.611756; doi: https://doi.org/10.1101/2024.09.06.611756 New Results

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Widespread naturally variable human exons aid genetic interpretation
Hannah Jacobs, Bram L. Gorissen, Jeremy Guez, Masahiro Kanai, Hilary K. Finucane, Konrad J. Karczewski, Christopher B. Burge

bioRxiv 2024.09.09.612029; doi: https://doi.org/10.1101/2024.09.09.612029 New Results

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Applying gradient tree boosting to QTL mapping with Shapley additive explanations
Tomohiro Ishibashi, Akio Onogi

bioRxiv 2024.01.15.575690; doi: https://doi.org/10.1101/2024.01.15.575690 New Results

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Imputed DNA methylation outperforms measured loci associations with smoking and chronological age
Anne Richmond, Jure Mur, Sarah E Harris, Janie Corley, Hannah R Elliott, Christopher N Foley, Eilis Hannon, Zhana Kuncheva, Josine L Min, Mahdi Moqri, Magatte Ndiaye, Benjamin B Sun, Catalina A Vallejos, Kejun Ying, Vadim N Gladyshev, Simon R Cox, Daniel L McCartney, Riccardo E Marioni

bioRxiv 2024.09.05.611501; doi: https://doi.org/10.1101/2024.09.05.611501 New Results

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Genetics

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