Genetics

Retinoblastoma binding protein 4 maintains cycling neural stem cells and prevents DNA damage and Tp53-dependent apoptosis in rb1 mutant neural progenitors
Laura E. Schultz-Rogers, Maira P. Almeida, Wesley A. Wierson, Marcel Kool, Maura McGrail

bioRxiv 427344; doi: https://doi.org/10.1101/427344 New Results
Identification of SMARCD1 as a syndromic intellectual disability gene that is required for memory and context-dependent regulation of neuronal genes in Drosophila
Kevin C.J. Nixon, Justine Rousseau, Max H. Stone, Mohammed Sarikahya, Sophie Ehresmann, Seiji Mizuno, Naomichi Matsumoto, Noriko Miyake, DDD Study, Diana Baralle, Shane McKee, Kosuke Izumi, Alyssa Ritter, Solveig Heide, Delphine Héron, Christel Depienne, Hannah Titheradge, Jamie M. Kramer, Philippe M. Campeau

bioRxiv 422188; doi: https://doi.org/10.1101/422188 New Results
Parentage assignment with genotyping-by-sequencing data
Andrew Whalen, Gregor Gorjanc, John Hickey

bioRxiv 270561; doi: https://doi.org/10.1101/270561 New Results
Simulating Pedigrees Ascertained for Multiple Disease-Affected Relatives
Christina Nieuwoudt, Samantha J Jones, Angela Brooks-Wilson, Jinko Graham

bioRxiv 234153; doi: https://doi.org/10.1101/234153 New Results
REC114 partner ANKRD31 controls number, timing and location of meiotic DNA breaks
Michiel Boekhout, Mehmet E. Karasu, Juncheng Wang, Laurent Acquaviva, Florencia Pratto, Kevin Brick, Diana Y. Eng, R. Daniel Camerini-Otero, Dinshaw J. Patel, Scott Keeney

bioRxiv 425322; doi: https://doi.org/10.1101/425322 New Results
A systematic review and standardized clinical validity assessment of male infertility genes
Manon S Oud, Ludmila Volozonoka, Roos M Smits, Lisenka ELM Vissers, Liliana Ramos, Joris A Veltman

bioRxiv 425553; doi: https://doi.org/10.1101/425553 New Results
Noninvasive prenatal test of methylmalonic academia cblC type through targeted sequencing of cell-free DNA in maternal plasma
Chao Chen, Lianshu Han, Fengyu Guo, Jun Ye, Zhiyu Peng, Yaoshen Wang, Wenjuan Qiu, Wei Li, Huiwen Zhang, Lili Liang, Yu Wang, Huanhuan Wang, Xing Ji, Jun Sun, Xuefan Gu

bioRxiv 425918; doi: https://doi.org/10.1101/425918 New Results
Trans effects on gene expression can drive omnigenic inheritance
Xuanyao Liu, Yang I Li, Jonathan K Pritchard

bioRxiv 425108; doi: https://doi.org/10.1101/425108 New Results
Architecture of a multi-cellular polygenic network governing immune homeostasis
Tania Dubovik, Elina Starosvetsky, Benjamin LeRoy, Rachelly Normand, Yasmin Admon, Ayelet Alpert, Yishai Ofran, Max G'Sell, Shai S. Shen-Orr

bioRxiv 256073; doi: https://doi.org/10.1101/256073 New Results
Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 are associated with gestational duration
Xueping Liu, Dorte Helenius, Line Skotte, Robin N Beaumont, Matthias Wielscher, Frank Geller, Julius Juodakis, Anubha Mahajan, Jonathan P. Bradfield, Frederick T.J. Lin, Suzanne Vogelezang, Mariona Bustamante, Tarunveer S Ahluwalia, Niina Pitkänen, Carol A. Wang, Jonas Bacelis, Maria C. Borges, Ge Zhang, Bruce A. Bedell, Robert M. Rossi, Kristin Skogstrand, Shouneng Peng, Early Growth Genetics (EGG) Consortium, iPSYCH-BROAD Working Group, Wesley K. Thompson, Vivek Appadurai, Deborah A Lawlor, Ilkka Kalliala, Christine Power, Mark I. McCarthy, Heather A. Boyd, Mary L. Marazita, Hakon Hakonarson, M. Geoffrey Hayes, Denise M. Scholtens, Fernando Rivadeneira, Vincent W.V. Jaddoe, Rebecca K. Vinding, Hans Bisgaard, Bridget A. Knight, Katja Pahkala, Olli Raitakari, Øyvind Helgeland, Stefan Johansson, Pål R. Njølstad, João Fadista, Andrew Schork, Ron Nudel, Daniel E. Miller, Xiaoting Chen, Matthew Weirauch, Preben Bo Mortensen, Anders D. Børglum, Merete Nordentoft, Ole Mors, Ke Hao, Kelli K. Ryckman, David M. Hougaard, Leah Kottyan, Craig E. Pennell, Leo-Pekka Lyytikainen, Klaus Bønnelykke, Martine Vrijheid, Janine F. Felix, William L. Lowe Jr., Struan F.A. Grant, Elina Hyppönen, Bo Jacobsson, Marjo-Riitta Jarvelin, Louis J. Muglia, Jeffrey C. Murray, Rachel M. Freathy, Thomas M. Werge, Mads Melbye, Alfonso Buil, Bjarke Feenstra

bioRxiv 423897; doi: https://doi.org/10.1101/423897 New Results

Genetics

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