Genetics

Factorizing polygenic epistasis improves prediction and uncovers biological pathways in complex traits
David Tang, Jerome Freudenberg, Andy Dahl

bioRxiv 2022.11.29.518075; doi: https://doi.org/10.1101/2022.11.29.518075 New Results

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Inorganic polyphosphate abets silencing of a sub-telomeric gene cluster in fission yeast
Ana M Sanchez, Angad Garg, Beate Schwer, Stewart Shuman

bioRxiv 2022.11.28.517416; doi: https://doi.org/10.1101/2022.11.28.517416 New Results

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POIROT: A powerful test for parent-of-origin effects in unrelated samples leveraging multiple phenotypes
S. Taylor Head, Elizabeth J. Leslie, David J. Cutler, Michael P. Epstein

bioRxiv 2022.11.28.517712; doi: https://doi.org/10.1101/2022.11.28.517712 New Results

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Repurposing antihypertensive, lipid-lowering and antidiabetic drugs for lacunar stroke
Linjing Zhang, Kailin Xia, Zhou Yu, Yu Fu, Tao Huang, Dongsheng Fan

bioRxiv 2022.11.28.518274; doi: https://doi.org/10.1101/2022.11.28.518274 New Results

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Review and further developments in statistical corrections for Winner's Curse in genetic association studies
Amanda Forde, Gibran Hemani, John Ferguson

bioRxiv 2022.11.28.518299; doi: https://doi.org/10.1101/2022.11.28.518299 New Results

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The algorithm for proven and young (APY) from a different perspective
Mohammad Ali Nilforooshan

bioRxiv 2022.11.23.517757; doi: https://doi.org/10.1101/2022.11.23.517757 New Results

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Distinct Differences in Gene Expression Profiles in Early and Late Stage Rhodesiense HAT Individuals in Malawi
Peter Nambala, Julius Mulindwa, Harry Noyes, Joyce Namulondo, Oscar Nyangiri, Enock Matovu, Annette MacLeod, Janelisa Musaya

bioRxiv 2022.11.28.518140; doi: https://doi.org/10.1101/2022.11.28.518140 New Results

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Zebrafish screen of high-confidence effector genes at insomnia GWAS loci implicates conserved regulators of sleep-wake behaviors
Amber J. Zimmerman, Fusun Doldur-Balli, Brendan T. Keenan, Zoe Y. Shetty, Justin Palermo, Alessandra Chesi, Shilpa Sonti, Matthew C. Pahl, Elizabeth B. Brown, James A. Pippin, Andrew D. Wells, Olivia J. Veatch, Diego R. Mazzotti, Anitra Krishnan, Phillip R. Gehrman, Alex C. Keene, Struan F.A. Grant, Allan I. Pack

bioRxiv 2022.10.05.511011; doi: https://doi.org/10.1101/2022.10.05.511011 New Results

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Generate a new crucian carp (Carassius auratus) strain without intermuscular bones by knocking out bmp6
Youy Kuang, Xianhu Zheng, Dingchen Cao, Zhipeng Sun, Guangxiang Tong, Huan Xu, Ting Yan, Shizhan Tang, Zhongxiang Chen, Tingting Zhang, Tan Zhang, Le Dong, Xiaoxing Yang, Huijie Zhou, Weilun Guo, Xiaowen Sun

bioRxiv 2022.11.28.518130; doi: https://doi.org/10.1101/2022.11.28.518130 New Results

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Multi-environment analysis enhances genomic prediction accuracy of agronomic traits in sesame
Idan Sabag, Ye Bi, Zvi Peleg, Gota Morota

bioRxiv 2022.11.26.518043; doi: https://doi.org/10.1101/2022.11.26.518043 New Results

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Genetics

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