Genetics

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  • Risky behaviors and Parkinson's disease: A Mendelian randomization study in up to 1 million study participants
    Sandeep Grover, Fabiola Del Greco M, Meike Kasten, Christine Klein, Christina M Lill, Inke R. Koenig
    bioRxiv 446807; doi: https://doi.org/10.1101/446807 New Results
  • A mixed-model approach for powerful testing of genetic associations with cancer risk incorporating tumor characteristics
    Haoyu Zhang, Ni Zhao, Thomas U. Ahearn, William Wheeler, Montserrat Garcia-Closas, Nilanjan Chatterjee
    bioRxiv 446039; doi: https://doi.org/10.1101/446039 New Results
  • The glucocorticoid receptor ligand-binding domain confers drug-gated protein regulation in C. elegans
    Gabriela C. Monsalve, Keith R. Yamamoto, Jordan D Ward
    bioRxiv 445833; doi: https://doi.org/10.1101/445833 New Results
  • Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors
    Nicole M Warrington, Robin Beaumont, Momoko Horikoshi, Felix R Day, Øyvind Helgeland, Charles Laurin, Jonas Bacelis, Shouneng Peng, Ke Hao, Bjarke Feenstra, Andrew R Wood, Anubha Mahajan, Jess Tyrrell, Neil Robertson, N William Rayner, Zhen Qiao, Gunn-Helen Øiseth Moen, Marc Vaudel, Carmen J Marsit, Jia Chen, Michael Nodzenski, Theresia M Schnurr, Mohammad H Zafarmand, Jonathan P Bradfield, Niels Grarup, Marjolein N Kooijman, Ruifang Li-Gao, Frank Geller, Tarunveer S Ahluwalia, Lavinia Paternoster, Rico Rueedi, Ville Huikari, Jouke-Jan Hottenga, Leo-Pekka Lyytikäinen, Alana Cavadino, Sarah Metrustry, Diana L Cousminer, Ying Wu, Elisabeth Thiering, Carol A Wang, Christian T Have, Natalia Vilor-Tejedor, Peter Joshi, Jodie N Painter, Ioanna Ntalla, Ronny Myhre, Niina Pitkänen, Elisabeth M van Leeuwen, Raimo Joro, Vasiliki Lagou, Rebecca Richmond, Ana Espinosa, Sheila J Barton, Hazel M Inskip, John W Holloway, Loreto Santa-Marina, Xavier Estivill, Wei Ang, Julie A Marsh, Christoph Reichetzeder, Letizia Marullo, Berthold Hocher, Kathryn L Lunetta, Joanne M Murabito, Caroline L Relton, Manolis Kogevinas, Leda Chatzi, Catherine Allard, Luigi Bouchard, Marie-France Hivert, Ge Zhang, Louis J Muglia, Jani Heikkinen, Camilla S Morgen, Antoine HC van Kampen, Barbera DC van Shaik, Frank D Mentch, Claudia Langenberg, Jian'an Luan, Robert A Scott, Jing Hua Zhao, Gibran Hemani, Susan M Ring, Amanda J Bennett, Kyle J Gaulton, Juan Fernandez-Tajes, Natalie R van Zuydam, Carolina Medina-Gomez, Hugoline G de Haan, Frits R Rosendaal, Zoltán Kutalik, Pedro Marques-Vidal, Shikta Das, Gonneke Willemsen, Hamdi Mbarek, Martina Müller-Nurasyid, Marie Standl, Emil VR Appel, Cilius E Fonvig, Caecilie Trier, Catharina EM van Beijsterveldt, Mario Murcia, Mariona Bustamante, Sílvia Bonas-Guarch, David M Hougaard, Josep M Mercader, Allan Linneberg, Katharina E Schraut, Penelope A Lind, Sarah E Medland, Beverley M Shields, Bridget A Knight, Jin-Fang Chai, Kalliope Panoutsopoulou, Meike Bartels, Friman Sánchez, Jacob Stokholm, David Torrents, Rebecca K Vinding, Inga Prokopenko, Marcus A Tuke, Hanieh Yaghootkar, Katherine S Ruth, Samuel E Jones, Po-Ru Loh, Anna Murray, Michael N Weedon, Anke Tonjes, Michael Stumvoll, Kim F Michaelsen, Aino-Maija Eloranta, Timo A Lakka, Cornelia M van Duijn, Wieland Kiess, Antje Körner, Harri Niinikoski, Katja Pahkala, Olli T Raitakari, Bo Jacobsson, Eleftheria Zeggini, George V Dedoussis, Yik-Ying Teo, Seang-Mei Saw, Grant W Montgomery, Harry Campbell, James F Wilson, Tanja GM Vrijkotte, Martine Vrijheid, Eco JCN de Geus, M Geoffrey Hayes, Haja N Kadarmideen, Jens-Christian Holm, Lawrence J Beilin, Craig E Pennell, Joachim Heinrich, Linda S Adair, Judith B Borja, Karen L Mohlke, Johan G Eriksson, Elisabeth E Widen, Andrew T Hattersley, Tim D Spector, Mika Kahonen, Jorma S Viikari, Terho Lehtimaki, Dorret I Boomsma, Sylvain Sebert, Peter Vollenweider, Thorkild IA Sørensen, Hans Bisgaard, Klaus Bønnelykke, Jeffrey C Murray, Mads Melbye, Ellen A Nohr, Dennis O Mook-Kanamori, Fernando Rivadeneira, Albert Hofman, Janine F Felix, Vincent VW Jaddoe, Torben Hansen, Charlotta Pisinger, Allan A Vaag, Oluf Pedersen, Andre G Uitterlinden, Marjo-Riitta Jarvelin, Christine Power, Elina Hyppönen, Denise M Scholtens, William L Lowe Jr., George Davey Smith, Nicholas J Timpson, Andrew P Morris, Nicholas J Wareham, Hakon Hakonarson, Struan FA Grant, Timothy M Frayling, Debbie A Lawlor, Pål R Njølstad, Stefan Johansson, Ken K Ong, Mark I McCarthy, John RB Perry, David M Evans, Rachel M Freathy
    bioRxiv 442756; doi: https://doi.org/10.1101/442756 New Results
  • Reverse GWAS: Using Genetics to Identify and Model Phenotypic Subtypes
    Andy Dahl, Na Cai, Arthur Ko, Markku Laakso, Paivi Pajukanta, Jonathan Flint, Noah Zaitlen
    bioRxiv 446492; doi: https://doi.org/10.1101/446492 New Results
  • Highly Structured Homolog Pairing Reflects Functional Organization of the Drosophila Genome
    Jumana AlHaj Abed, Jelena Erceg, Anton Goloborodko, Son C. Nguyen, Ruth B. McCole, Wren Saylor, Geoffrey Fudenberg, Bryan R. Lajoie, Job Dekker, Leonid A. Mirny, Ting (C.-ting) Wu
    bioRxiv 443887; doi: https://doi.org/10.1101/443887 New Results
  • The genome-wide, multi-layered architecture of chromosome pairing in early Drosophila embryos
    Jelena Erceg, Jumana AlHaj Abed, Anton Goloborodko, Bryan R. Lajoie, Geoffrey Fudenberg, Nezar Abdennur, Maxim Imakaev, Ruth B. McCole, Son C. Nguyen, Wren Saylor, Eric F. Joyce, T. Niroshini Senaratne, Mohammed A. Hannan, Guy Nir, Job Dekker, Leonid A. Mirny, Chao-ting Wu
    bioRxiv 443028; doi: https://doi.org/10.1101/443028 New Results
  • Variably methylated regions in the newborn epigenome: environmental, genetic and combined influences
    Darina Czamara, Gökcen Eraslan, Jari Lahti, Christian M Page, Marius Lahti-Pulkkinen, Esa Hämäläinen, Eero Kajantie, Hannele Laivuori, Pia M Villa, Rebecca M Reynolds, Wenche Nystad, Siri E Haberg, Stephanie J London, Kieran J O'Donnell, Elika Garg, Michael J Meaney, Sonja Entringer, Pathik D Wadhwa, Claudia Buss, Meaghan J Jones, David TS Lin, Julie L MacIsaac, Michael S Kobor, Nastassja Koen, Heather J Zar, Karestan C Koenen, Shareefa Dalvie, Dan J Stein, Ivan Kondofersky, Nikola S Mueller, Fabian J Theis, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Katri Räikkönen, Elisabeth B Binder
    bioRxiv 436113; doi: https://doi.org/10.1101/436113 New Results
  • The RNA-binding ATPase, Armitage, Couples piRNA Amplification in Nuage to Phased piRNA Production on Mitochondria
    Daniel Tianfang Ge, Wei Wang, Cindy Tipping, Ildar Gainetdinov, Zhiping Weng, Phillip D Zamore
    bioRxiv 445825; doi: https://doi.org/10.1101/445825 New Results
  • The PAGE Study: How Genetic Diversity Improves Our Understanding of the Architecture of Complex Traits
    Genevieve Wojcik, Mariaelisa Graff, Katherine K Nishimura, Ran Tao, Jeffrey Haessler, Christopher R Gignoux, Heather M Highland, Yesha M Patel, Elena P Sorokin, Christy L Avery, Gillian M Belbin, Stephanie A Bien, Iona Cheng, Sinead Cullina, Chani J Hodonsky, Yao Hu, Laura M Huckins, Janina Jeff, Anne E Justice, Jonathan M Kocarnik, Unhee Lim, Bridget M Lin, Yingchang Lu, Sarah C Nelson, Sung-Shim L Park, Hannah Poisner, Michael H Preuss, Melissa A Richard, Claudia Schurmann, Veronica W Setiawan, Alexandra Sockell, Karan Vahi, Abhishek Vishnu, Marie Verbanck, Ryan Walker, Kristin L Young, Niha Zubair, Victor Acuna-Alonso, Jose Luis Ambite, Kathleen C Barnes, Eric Boerwinkle, Erwin Bottinger, Carlos D Bustamante, Christian Caberto, Samuel Canizales-Quinteros, Matthew P Conomos, Ewa Deelman, Ron Do, Kimberly Doheny, Lindsay Fernandez-Rhodes, Myriam Fornage, Gerardo Heiss, Brenna M Henn, Lucia A Hindorff, Rebecca D Jackson, Benyam Hailu, Cecelia A Laurie, Cathy C Laurie, Yuqing Li, Dan-Yu Lin, Andres Moreno-Estrada, Girish Nadkarni, Paul J Norman, Loreall C Pooler, Alexander P Reiner, Jane Romm, Chiara Sabati, Karla Sandoval, Xin Sheng, Eli A Stahl, Daniel O Stram, Timothy A Thornton, Christina L Wassel, Lynne R Wilkens, Cheryl A Winkler, Sachi Yoneyama, Steven Buyske, Chris Haiman, Charles Kooperberg, Loic Le Marchand, Ruth JF Loos, Tara C Matise, Kari E North, Ulrike Peters, Eimear E Kenny, Christopher S Carlson
    bioRxiv 188094; doi: https://doi.org/10.1101/188094 New Results

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