Genetics

Genetic comorbidity between major depression and cardio-metabolic disease, stratified by age at onset of major depression.
Saskia P Hagenaars, Jonathan R I Coleman, Sam Choi, Helena A Gaspar, Mark J Adams, David Howard, Karen Hodgson, Matthew Traylor, Tracy M Air, Till F M Andlauer, Volker Arolt, Bernhard T Baune, Elisabeth B Binder, Douglas H R Blackwood, Dorret I Boomsma, Archie Campbell, M Cearns, Darina Czamara, Udo Dannlowski, Katharina Domschke, Eco J C de Geus, Steven P Hamilton, Caroline Hayward, Ian Hickie, Jouke J Hottenga, Marcus Ising, Ian Jones, Lisa A Jones, Zoltán Kutalik, Susanne Lucae, Nicholas Martin, Yuri Milaneschi, Bertram Mueller-Myhsok, Michael J Owen, Sandosh Padmanabhan, Brenda W J H Penninx, Giorgio Pistis, David J Porteous, Martin Preisig, Stephan Ripke, Stanley I Shyn, Patrick F Sullivan, John Whitfield, Naomi R Wray, Major Depressive Disorder Working Group of the Psy, MEGASTROKE consortium, Andrew M McIntosh, Ian J Deary, Gerome Breen, Cathryn M Lewis

bioRxiv 645077; doi: https://doi.org/10.1101/645077 New Results
Is it reasonable to account for population structure in genome-wide association studies?
Bongsong Kim

bioRxiv 647768; doi: https://doi.org/10.1101/647768 New Results
A Novel Type 2 Diabetes Locus in sub-Saharan Africans, ZRANB3, is Implicated in Beta Cell Proliferation
Adebowale A. Adeyemo, Guanjie Chen, Ayo P. Doumatey, Timothy L. Hostelley, Carmen C. Leitch, Jie Zhou, Amy R. Bentley, Daniel Shriner, Olufemi Fasanmade, Godfrey Okafor, Benjamin Eghan Jr., Kofi Agyenim-Boateng, Settara Chandrasekharappa, Jokotade Adeleye, William Balogun, Samuel Owusu, Albert Amoah, Joseph Acheampong, Thomas Johnson, Johnnie Oli, Clement Adebamowo, South Africa Zulu Type 2 Diabetes Case-Control Stu, Francis Collins, Georgia Dunston, Norann A. Zaghloul, Charles N. Rotimi

bioRxiv 646513; doi: https://doi.org/10.1101/646513 New Results
Phlebotomus papatasi sand fly salivary protein diversity and immune response potential in Egypt and Jordan populations
Catherine Flanley, Marcelo Ramalho-Ortigao, Iliano Coutinho-Abreu, Rami Mukbel, Hanafi Hanafi, Shabaan El-Hossary, Emadeldin Fawaz, David Hoel, Alexander Bray, Gwen Stayback, Douglas Shoue, Shaden Kamhawi, Scott Emrich, Mary Ann McDowell

bioRxiv 649517; doi: https://doi.org/10.1101/649517 New Results
Phenotypic and genotypic consequences of CRISPR/Cas9 editing of the replication origins in the rDNA of Saccharomyces cerevisiae
Joseph C. Sanchez, Anja Ollodart, Christopher R. L. Large, Courtnee Clough, Gina M. Alvino, Mitsuhiro Tsuchiya, Matthew Crane, Elizabeth X. Kwan, Matt Kaeberlein, Maitreya J. Dunham, M. K. Raghuraman, Bonita J. Brewer

bioRxiv 647495; doi: https://doi.org/10.1101/647495 New Results
Female meiotic drive preferentially segregates derived metacentric chromosomes in Drosophila
Nicholas B. Stewart, Yasir H. Ahmed-Braimah, Daniel G. Cerne, Bryant F. McAllister

bioRxiv 638684; doi: https://doi.org/10.1101/638684 New Results
Can education be personalised using pupils’ genetic data?
Tim T Morris, Neil M Davies, George Davey Smith

bioRxiv 645218; doi: https://doi.org/10.1101/645218 New Results
The loci of behavioral evolution: evidence that Fas2 and tilB underlie differences in pupation site choice behavior between Drosophila melanogaster and D. simulans
Alison Pischedda, Michael P. Shahandeh, Thomas L. Turner

bioRxiv 494013; doi: https://doi.org/10.1101/494013 New Results
Genome-wide association study in two cohorts from a multi-generational mouse advanced intercross line highlights the difficulty of replication
Xinzhu Zhou, Celine L. St. Pierre, Natalia M. Gonzales, Riyan Cheng, Apurva Chitre, Greta Sokoloff, Abraham A. Palmer

bioRxiv 387613; doi: https://doi.org/10.1101/387613 New Results
No evidence for social genetic effects or genetic similarity among friends beyond that due to population stratification: a reappraisal of Domingue et al (2018)
Loic Yengo, Morgan Sidari, Karin J. H. Verweij, Peter M. Visscher, Matthew C. Keller, Brendan P. Zietsch

bioRxiv 643304; doi: https://doi.org/10.1101/643304 Contradictory Results

Genetics

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