Genetics

Genetic sequences are two-dimensional
Albert J Erives

bioRxiv 299867; doi: https://doi.org/10.1101/299867 New Results
Brain scans from 21297 individuals reveal the genetic architecture of hippocampal subfield volumes
Dennis van der Meer, Jaroslav Rokicki, Tobias Kaufmann, Aldo Cordova Palomera, Torgeir Moberget, Dag Alnaes, Francesco Bettella, Oleksandr Frei, Nhat Trung Doan, Ingrid Agartz, Alessandro Bertolino, Janita Bralten, Christine Brandt, Jan Buitelaar, Srdjan Djurovic, Marjolein van Donkelaar, Erlend Dorum, Thomas Espeseth, Stephen Faraone, Guillen Fernandez, Simon Fisher, Barbara Franke, Beathe Haatveit, Catharina Hartman, Pieter Hoekstra, Asta Haberg, Erik Jonsson, Knut Kolskaar, Stephanie Le Hellard, Martina Lund, Astri Lundervold, Arvid Lundervold, Ingrid Melle, Jennifer Monereo Sanchez, Linn Norbom, Jan Nordvik, Lars Nyberg, Jaap Oosterlaan, Marco Papalino, Andreas Papassotiropoulos, Giulio Pergola, Dominique de Quervain, Genevieve Richard, Anne Marthe Sanders, Pierluiggi Selvaggi, Elena Shumskaya, Vidar Steen, Siren Tonnesen, Kristine Ulrichsen, Marcel Zwiers, Ole Andreassen, Lars Westlye

bioRxiv 299578; doi: https://doi.org/10.1101/299578 New Results
Common genetic variants and health outcomes appear geographically structured in the UK Biobank sample: Old concerns returning and their implications.
Simon Haworth, Ruth Mitchell, Laura Corbin, Kaitlin H Wade, Tom Dudding, Ashley Budu-Aggrey, David Carslake, Gibran Hemani, Lavinia Paternoster, George Davey Smith, Neil Davies, Dan Lawson, Nicholas Timpson

bioRxiv 294876; doi: https://doi.org/10.1101/294876 New Results
Acute effects of drugs on C. elegans movement reveal complex responses and plasticity
Mark A Spensley, Samantha Del Borrello, Djina Pajkic, Andrew G Fraser

bioRxiv 299719; doi: https://doi.org/10.1101/299719 New Results
Extensive cellular heterogeneity of X inactivation revealed by single-cell allele-specific expression in human fibroblasts.
Marco Garieri, Georgios Stamoulis, Emilie Falconnet, Pascale Ribaux, Christelle Borel, Federico A Santoni, Stylianos E Antonarakis

bioRxiv 298984; doi: https://doi.org/10.1101/298984 New Results
Robustness of bristle number to temperature and genetic background varies with bristle type and is regulated by miR-9a.
Alexis Matamoro-Vidal, Thomas Tully, Virginie Courtier-Orgogozo

bioRxiv 295485; doi: https://doi.org/10.1101/295485 New Results
Prioritizing putative influential genes in early life cardiovascular disease susceptibility by applying tissue-specific Mendelian randomization
Kurt Taylor, George Davey Smith, Caroline L Relton, Tom R Gaunt, Tom G Richardson

bioRxiv 298687; doi: https://doi.org/10.1101/298687 New Results
Telomere length set point regulation in human pluripotent stem cells critically depends on the shelterin protein TPP1
John Michael Boyle, Kelsey M Hennick, Samuel G Regalado, Jacob Vogan, Xiaozhu Zhang, Kathleen Collins, Dirk Hockemeyer

bioRxiv 298778; doi: https://doi.org/10.1101/298778 New Results
Heritability and genome-wide association study of diffusing capacity of the lung
Natalie Terzikhan, Fangui Sun, Fien Verhamme, Hieab H.H. Adams, Daan Loth, Ken Bracke, Bruno Stricker, Lies Lahousse, Dupuis Josee, Guy Brusselle, Greorge T O'Conner

bioRxiv 277343; doi: https://doi.org/10.1101/277343 New Results
The Drosophila mitochondrial citrate carrier regulates L-2-hydroxyglutarate accumulation by coupling the tricarboxylic acid cycle with glycolysis
Jason M Tennessen, Hongde Li, Alex J. Hurlburt

bioRxiv 297705; doi: https://doi.org/10.1101/297705 New Results

Genetics

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