Genetics

Polygenic risk of psychiatric disorders exhibits cross-trait associations in electronic health record data
Rachel L. Kember, Alison K. Merikangas, Shefali S. Verma, Anurag Verma, Renae Judy, Regeneron Genetics Center, Scott M. Damrauer, Marylyn D. Ritchie, Daniel J. Rader, Maja Bućan

bioRxiv 858027; doi: https://doi.org/10.1101/858027 New Results

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Differential efficacies of Cas nucleases on microsatellites involved in human disorders and associated off-target mutations
Lucie Poggi, Lisa Emmenegger, Stéphane Descorps-Declère, Bruno Dumas, Guy-Franck Richard

bioRxiv 857714; doi: https://doi.org/10.1101/857714 New Results

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PhenoMIP: High Throughput Phenotyping of Diverse C. elegans Populations via Molecular Inversion Probes
Calvin Mok, Gabriella Belmarez, Mark L. Edgley, Donald G. Moerman, Robert H. Waterston

bioRxiv 857854; doi: https://doi.org/10.1101/857854 New Results

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Minimized double guide RNA libraries enable scale-limited CRISPR/Cas9 screens
Elin Madli Peets, Luca Crepaldi, Yan Zhou, Felicity Allen, Rasa Elmentaite, Guillaume Noell, Gemma Turner, Vivek Iyer, Leopold Parts

bioRxiv 859652; doi: https://doi.org/10.1101/859652 New Results

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High-throughput reclassification of SCN5A variants
Andrew M. Glazer, Yuko Wada, Bian Li, Ayesha Muhammad, Olivia R. Kalash, Matthew J. O’Neill, Tiffany Shields, Lynn Hall, Laura Short, Marcia A. Blair, Brett M. Kroncke, John A. Capra, Dan M. Roden

bioRxiv 858175; doi: https://doi.org/10.1101/858175 New Results

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Whole genome sequencing analysis of the cardiometabolic proteome
Arthur Gilly, Young-Chan Park, Grace Png, Thea Bjornland, Lorraine Southam, Daniel Suveges, Sonja Neumeyer, Iris Fischer, Andrei Barysenka, N. William Rayner, Emmanouil Tsafantakis, Maria Karaleftheri, George Dedoussis, Eleftheria Zeggini

bioRxiv 854752; doi: https://doi.org/10.1101/854752 New Results

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Genome-wide identification of a regulatory mutation in BMP15 controlling prolificacy in sheep
Louise Chantepie, Loys Bodin, Julien Sarry, Florent Woloszyn, Florence Plisson-Petit, Julien Ruesche, Laurence Drouilhet, Stéphane Fabre

bioRxiv 858860; doi: https://doi.org/10.1101/858860 New Results

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Cross-disorder genetic analyses implicate dopaminergic signaling as a biological link between Attention-Deficit/Hyperactivity Disorder and obesity measures
Nina Roth Mota, Geert Poelmans, Marieke Klein, Bàrbara Torrico, Noèlia Fernàndez-Castillo, Bru Cormand, Andreas Reif, Barbara Franke, Alejandro Arias Vásquez

bioRxiv 573808; doi: https://doi.org/10.1101/573808 New Results

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An accurate molecular method to sex elephants using PCR amplification of Amelogenin gene
George Gwaltu Lohay

bioRxiv 856419; doi: https://doi.org/10.1101/856419 New Results

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Jointly inferring the dynamics of population size and sampling intensity from molecular sequences
KV Parag, L du Plessis, OG Pybus

bioRxiv 686378; doi: https://doi.org/10.1101/686378 New Results

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Genetics

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