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Genetics

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  • The genetic basis of host choice and resting behavior in the major African malaria vector, Anopheles arabiensis
    Bradley J Main, Yoosook Lee, Heather M Ferguson, Katharina S Kreppel, Anicet Kihonda, Nicodem J Govella, Travis C Collier, Anthony J Cornel, Eleazar Eskin, Eun Yong Kang, Catelyn C Nieman, Allison M Weakley, Gregory C Lanzaro
    bioRxiv 044701; doi: https://doi.org/10.1101/044701
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  • Ultra-rare disruptive and damaging mutations influence educational attainment in the general population
    Andrea Ganna, Giulio Genovese, Daniel P. Howrigan, Andrea Byrnes, Mitja Kurki, Seyedeh M. Zekavat, Christopher W. Whelan, Mart Kals, Michel G. Nivard, Alex Bloemendal, Jonathan M. Bloom, Jacqueline I. Goldstein, Timothy Poterba, Cotton Seed, Robert E. Handsaker, Pradeep Natarajan, Reedik Mägi, Diane Gage, Elise B. Robinson, Andres Metspalu, Veikko Salomaa, Jaana Suvisaari, Shaun M. Purcell, Pamela Sklar, Sekar Kathiresan, Mark J. Daly, Steven A. McCarroll, Patrick F. Sullivan, Aarno Palotie, Tõnu Esko, Christina Hultman, Benjamin M. Neale
    bioRxiv 050195; doi: https://doi.org/10.1101/050195
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  • Playing Musical Chairs in Big Data to Reveal Variables’ Associations
    Hugues Aschard, Bjarni Vilhjalmsson, Chirag Patel, David Skurnik, Jimmy Yu, Brian Wolpin, Peter Kraft, Noah Zaitlen
    bioRxiv 057190; doi: https://doi.org/10.1101/057190
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  • Proteasome dysfunction triggers activation of SKN-1A/Nrf1 by the aspartic protease DDI-1
    Nicolas J. Lehrbach, Gary Ruvkun
    bioRxiv 052936; doi: https://doi.org/10.1101/052936
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  • Rare Variant Phasing and Haplotypic Expression from RNA-Sequencing with phASER
    Stephane E. Castel, Pejman Mohammadi, Wendy K. Chung, Yufeng Shen, Tuuli Lappalainen
    bioRxiv 039529; doi: https://doi.org/10.1101/039529
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  • Rapid, one-step generation of biallelic conditional gene knockouts
    Amanda Andersson-Rolf, Roxana C. Mustata, Alessandra Merenda, Sajith Perera, Tiago Grego, Jihoon Kim, Katie Andrews, Juergen Fink, William C. Skarnes, Bon-Kyoung Koo
    bioRxiv 056549; doi: https://doi.org/10.1101/056549
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  • Centromeres of the yeast Komagataella phaffii (Pichia pastoris) have a simple inverted-repeat structure
    Aisling Y. Coughlan, Sara J. Hanson, Kevin P. Byrne, Kenneth H. Wolfe
    bioRxiv 056382; doi: https://doi.org/10.1101/056382
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  • Large-scale trans-eQTLs affect hundreds of transcripts and mediate patterns of transcriptional co-regulation Short: trans-eQTLs reveal patterns of transcriptional co-regulation
    Boel Brynedal, JinMyung Choi, Towfique Raj, Robert Bjornson, Barbara E Stranger, Benjamin M Neale, Benjamin F Voight, Chris Cotsapas
    bioRxiv 056283; doi: https://doi.org/10.1101/056283
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  • The Effects of Migration and Assortative Mating on Admixture Linkage Disequilibrium
    Noah Zaitlen, Scott Huntsman, Donglei Hu, Melissa Spear, Celeste Eng, Sam S. Oh, Marquitta J White, Angel Mak, Adam Davis, Kelly Meade, Emerita Brigino-Buenaventura, Michael A LeNoir, Kirsten Bibbins-Domingo, Esteban G Burchard, Eran Halperin
    bioRxiv 056168; doi: https://doi.org/10.1101/056168
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  • Population structure of UK Biobank and ancient Eurasians reveals adaptation at genes influencing blood pressure
    Kevin J. Galinsky, Po-Ru Loh, Mallick Swapan, Nick J. Patterson, Alkes L. Price
    bioRxiv 055855; doi: https://doi.org/10.1101/055855
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