Genomics

Combined reference-free and multi-reference approaches uncover cryptic variation underlying rapid adaptation in microbial pathogens
Anik Dutta, Bruce A. McDonald, Daniel Croll

bioRxiv 2022.05.16.492091; doi: https://doi.org/10.1101/2022.05.16.492091 New Results

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Near-chromosomal de novo assembly of Bengal tiger genome reveals genetic hallmarks of apex-predation
Harsh Shukla, Kushal Suryamohan, Anubhab Khan, Krishna Mohan, Rajadurai C. Perumal, Oommen K. Mathew, Ramesh Menon, Mandumpala Davis Dixon, Megha Muraleedharan, Boney Kuriakose, Saju Michael, Sajesh P. Krishnankutty, Arun Zachariah, Somasekar Seshagiri, Uma Ramakrishnan

bioRxiv 2022.05.14.491975; doi: https://doi.org/10.1101/2022.05.14.491975 New Results

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3D Chromatin Structure in Chondrocytes Identifies Putative Osteoarthritis Risk Genes
Eliza Thulson, Eric S. Davis, Susan D’Costa, Philip R. Coryell, Nicole E. Kramer, Karen L. Mohlke, Richard F. Loeser, Brian O. Diekman, Douglas H. Phanstiel

bioRxiv 2022.05.16.492146; doi: https://doi.org/10.1101/2022.05.16.492146 New Results

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Detailed investigation on the role of lipid metabolizing enzymes in the pathogenesis of retinopathy of prematurity among preterm infants
Saurabh Kumar, Satish Patnaik, Manjunath B Joshi, Subhadra Jalali, Komal Agarwal, Ramesh Kekunnaya, Subhabrata Chakrabarti, Inderjeet Kaur

bioRxiv 2022.05.13.491711; doi: https://doi.org/10.1101/2022.05.13.491711 New Results

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nnSVG: scalable identification of spatially variable genes using nearest-neighbor Gaussian processes
Lukas M. Weber, Arkajyoti Saha, Abhirup Datta, Kasper D. Hansen, Stephanie C. Hicks

bioRxiv 2022.05.16.492124; doi: https://doi.org/10.1101/2022.05.16.492124 New Results

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Improved SpCas9 and LbCas12a genome editing systems in Brassica oleracea and Brassica napus
Tom Lawrenson, Monika Chhetry, Martha Clarke, Penny Hundleby, Wendy Harwood

bioRxiv 2022.05.16.492057; doi: https://doi.org/10.1101/2022.05.16.492057 New Results

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Optical mapping compendium of structural variants across global cattle breeds
A. Talenti, J. Powell, D. Wragg, M. Chepkwony, A. Fisch, B.R. Ferreira, M.E.Z. Marcadante, I.M. Santos, C.K. Ezeasor, E.T. Obishakin, D. Muhanguzi, W. Amanyire, I. Silwamba, J.B. Muma, G. Mainda, R.F. Kelly, P. Toye, T. Connelley, J. Prendergast

bioRxiv 2022.05.05.490773; doi: https://doi.org/10.1101/2022.05.05.490773 New Results

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Increased gene dosage and mRNA expression from chromosomal duplications in C. elegans
Bhavana Ragipani, Sarah Elizabeth Albritton, Ana Karina Morao, Diogo Mesquita, Maxwell Kramer, Sevinç Ercan

bioRxiv 2022.03.22.485368; doi: https://doi.org/10.1101/2022.03.22.485368 New Results

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A global high-density chromatin interaction network reveals functional long-range and trans-chromosomal relationships
Ruchi Lohia, Nathan Fox, Jesse Gillis

bioRxiv 2022.03.24.485503; doi: https://doi.org/10.1101/2022.03.24.485503 New Results

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Tethering distinct molecular profiles of single cells by their lineage histories to investigate sources of cell state heterogeneity
Anna Minkina, Junyue Cao, Jay Shendure

bioRxiv 2022.05.12.491602; doi: https://doi.org/10.1101/2022.05.12.491602 New Results

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Genomics

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