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Genomics

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  • Interplay of cis and trans mechanisms driving transcription factor binding and gene expression evolution
    Emily S Wong, Bianca M Schmitt, Anastasiya Kazachenka, David Thybert, Aisling Redmond, Frances Connor, Tim F. Rayner, Christine Feig, Anne C. Ferguson-Smith, John C Marioni, Duncan T Odom, Paul Flicek
    bioRxiv 059873; doi: https://doi.org/10.1101/059873
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  • sNucDrop-Seq: Dissecting cell-type composition and neuronal activity state in mammalian brains by massively parallel single-nucleus RNA-Seq
    Peng Hu, Emily Fabyanic, Zhaolan Zhou, Hao Wu
    bioRxiv 154476; doi: https://doi.org/10.1101/154476
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  • Development of a targeted sequencing approach to identify prognostic, predictive and diagnostic markers in paediatric solid tumours
    Elisa Izquierdo, Lina Yuan, Sally George, Michael Hubank, Chris Jones, Paula Proszek, Janet Shipley, Susanne A Gatz, Caedyn Stinson, Andrew S. Moore, Steven C. Clifford, Debbie Hicks, Janet Lindsey, Rebecca Hill, Thomas S. Jacques, Jane Chalker, Khin Thway, Simon O’Connor, Lynley Marshall, Lucas Moreno, Andrew Pearson, Louis Chesler, Brian A. Walker, David Gonzalez De Castro
    bioRxiv 165746; doi: https://doi.org/10.1101/165746
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  • Divergent gene expression levels between diploid and autotetraploid Tolmiea (Saxifragaceae) relative to the total transcriptome, the cell, and biomass
    Clayton J. Visger, Gane K-S. Wong, Yong Zhang, Pamela S. Soltis, Douglas E. Soltis
    bioRxiv 169367; doi: https://doi.org/10.1101/169367
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  • The first near-complete assembly of the hexaploid bread wheat genome, Triticum aestivum
    Aleksey V. Zimin, Daniela Puiu, Richard Hall, Sarah Kingan, Bernardo J. Clavijo, Steven L. Salzberg
    bioRxiv 159111; doi: https://doi.org/10.1101/159111
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  • Mutual information estimation for transcriptional regulatory network inference
    Jonathan Ish-Horowicz, John Reid
    bioRxiv 132647; doi: https://doi.org/10.1101/132647 Confirmatory Results
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  • A large kinome in a large cell: Stentor coeruleus possesses highly expanded kinase families and novel domain architectures
    Sarah B. Reiff, Wallace F. Marshall
    bioRxiv 168187; doi: https://doi.org/10.1101/168187
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  • The effect of common inversion polymorphisms In(2L)t and In(3R)Mo on patterns of transcriptional variation in Drosophila melanogaster
    Erik Lavington, Andrew D. Kern
    bioRxiv 128926; doi: https://doi.org/10.1101/128926
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  • High-depth whole genome sequencing of a large population-specific reference panel: Enhancing sensitivity, accuracy, and imputation
    Todd Lencz, Jin Yu, Cameron Palmer, Shai Carmi, Danny Ben-Avraham, Nir Barzilai, Susan Bressman, Ariel Darvasi, Judy H. Cho, Lorraine N. Clark, Zeynep H. Gümüş, Vijai Joseph, Robert Klein, Steven Lipkin, Kenneth Offit, Harry Ostrer, Laurie J. Ozelius, Inga Peter, Gil Atzmon, Itsik Pe’er
    bioRxiv 167924; doi: https://doi.org/10.1101/167924
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  • Common patterns of gene regulation associated with Cesarean section and the development of islet autoimmunity – indications of immune cell activation
    M. Laimighofer, R. Lickert, R. Fürst, F. J. Theis, C. Winkler, E. Bonifacio, A.-G. Ziegler, J. Krumsiek
    bioRxiv 167676; doi: https://doi.org/10.1101/167676
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