Genomics

A comprehensive analysis of RNA sequences reveals macroscopic somatic clonal expansion across normal tissues
Keren Yizhak, Francois Aguet, Jaegil Kim, Julian Hess, Kirsten Kubler, Jonna Grimsby, Ruslana Frazer, Hailei Zhang, Nicholas Haradhvala, Daniel Rosebrock, Dimitri Livitz, Xiao Li, Eila Arich-Landkof, Noam Shoresh, Chip Stewart, Ayelet Segre, Philip Branton, Paz Polak, Kristin Ardlie, Gad Getz

bioRxiv 416339; doi: https://doi.org/10.1101/416339 New Results
Resource: Scalable whole genome sequencing of 40,000 single cells identifies stochastic aneuploidies, genome replication states and clonal repertoires
Emma Laks, Hans Zahn, Daniel Lai, Andrew McPherson, Adi Steif, Jazmine Brimhall, Justina Biele, Beixi Wang, Tehmina Masud, Diljot Grewal, Cydney Nielsen, Samantha Leung, Viktoria Bojilova, Maia Smith, Oleg Golovko, Steven Poon, Peter Eirew, Farhia Kabeer, Teresa Ruiz de Algara, So Ra Lee, M. Jafar Taghiyar, Curtis Huebner, Jessica Ngo, Tim Chan, Spencer Vatrt-Watts, Pascale Walters, Nafis Abrar, Sophia Chan, Matt Wiens, Lauren Martin, R. Wilder Scott, Michael T. Underhill, Elizabeth Chavez, Christian Steidl, Daniel Da Costa, Yusanne Ma, Robin J. N. Coope, Richard Corbett, Stephen Pleasance, Richard Moore, Andy J. Mungall, CRUK IMAXT Consortium, Marco A. Marra, Carl Hansen, Sohrab Shah, Samuel Aparicio

bioRxiv 411058; doi: https://doi.org/10.1101/411058 New Results
Dating genomic variants and shared ancestry in population-scale sequencing data
Patrick K. Albers, Gil McVean

bioRxiv 416610; doi: https://doi.org/10.1101/416610 New Results
Coupled single-cell CRISPR screening and epigenomic profiling reveals causal gene regulatory networks
Adam J Rubin, Kevin R Parker, Ansuman T Satpathy, Yanyan Qi, Beijing Wu, Alvin J Ong, Maxwell R Mumbach, Andrew L Ji, Daniel S Kim, Sueng Woo Cho, Brian J Zarnegar, William J Greenleaf, Howard Y Chang, Paul A Khavari

bioRxiv 414870; doi: https://doi.org/10.1101/414870 New Results
Inner Asian maternal genetic origin of the Avar period nomadic elite in the 7th century AD Carpathian Basin
Veronika Csáky, Dániel Gerber, István Koncz, Gergely Csiky, Balázs G. Mende, Antónia Marcsik, Erika Molnár, György Pálfi, András Gulyás, Bernadett Kovacsóczy, Gabriella M. Lezsák, Gábor Lőrinczy, Anna Szécsényi-Nagy, Tivadar Vida

bioRxiv 415760; doi: https://doi.org/10.1101/415760 New Results
Targetable genetic alterations of TCF4 (E2-2) drive immunoglobulin expression in the activated B-cell subtype of diffuse large B-cell lymphoma
Neeraj Jain, Keenan Hartert, Saber Tadros, Warren Fiskus, Ondrej Havranek, Man-Chun John Ma, Alyssa Bouska, Tayla Heavican, Dhiraj Kumar, Qing Deng, Dalia Moore, Christine Pak, Chi Long Liu, Andrew Gentles, Elena Hartmann, Robert Kridel, Karin Ekstrom-Smedby, Gunnar Juliusson, Richard Rosenquist, Randy Gascoyne, Andreas Rosenwald, Fillippo Giancotti, Sattva Neelapu, Jason Westin, Julie Vose, Matthew Lunning, Timothy Greiner, Scott Rodig, Javeed Iqbal, Ash Alizadeh, Richard Eric Davis, Kapil Bhalla, Michael Green

bioRxiv 170605; doi: https://doi.org/10.1101/170605 New Results
Origin and recent expansion of an endogenous gammaretroviral lineage in canids
Julia V. Halo, Amanda L. Pendleton, Abigail S. Jarosz, Robert J. Gifford, Malika L. Day, Jeffrey Kidd

bioRxiv 414607; doi: https://doi.org/10.1101/414607 New Results
Multiple QTL underlie milk phenotypes at the CSF2RB locus
Thomas J Lopdell, Kathryn Tiplady, Christine Couldrey, Thomas JJ Johnson, Michael Keehan, Stephen R Davis, Bevin L Harris, Richard J Spelman, Russell G Snell, Mathew D Littlejohn

bioRxiv 414821; doi: https://doi.org/10.1101/414821 New Results
DeepProteomics: Protein family classification using Shallow and Deep Networks
Anu Vazhayil, Vinayakumar R, Soman KP

bioRxiv 414631; doi: https://doi.org/10.1101/414631 New Results
Improved consistency in estimates of conditional false discovery rates increases power relative to both existing methods and parametric estimators
James Liley, Chris Wallace

bioRxiv 414326; doi: https://doi.org/10.1101/414326 New Results

Genomics

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