Genomics

The genome of C57BL/6J "Eve", the mother of the laboratory mouse genome reference strain
Vishal Kumar Sarsani, Narayanan Raghupathy, Ian T Fiddes, Joel Armstrong, Francoise Thibaud-Nissen, Oraya Zinder, Mohan Bolisetty, Kerstin Howe, Doug Hinerfeld, Xiaoan Ruan, Lucy Rowe, Mary Barter, Guruprasad Ananda, Benedict Paten, George M. Weinstock, Gary A. Churchill, Michael V. Wiles, Valerie A. Schneider, Anuj Srivastava, Laura Reinholdt

bioRxiv 517466; doi: https://doi.org/10.1101/517466 New Results
Tumor mutational landscape is a record of the pre-malignant state
Kirsten Kübler, Rosa Karlić, Nicholas J. Haradhvala, Kyungsik Ha, Jaegil Kim, Maja Kuzman, Wei Jiao, Sitanshu Gakkhar, Kent W. Mouw, Lior Z. Braunstein, Olivier Elemento, Andrew V. Biankin, Ilse Rooman, Mendy Miller, Wouter R. Karthaus, Christopher D. Nogiec, Edouard Juvenson, Edward Curry, Mari Mino-Kenudson, Leif W. Ellisen, Robert Brown, Alexander Gusev, Cristian Tomasetti, Martijn P. Lolkema, Neeltje Steeghs, Carla van Herpen, Hong-Gee Kim, Hwajin Lee, Kristian Vlahoviček, Bradley E. Bernstein, Charles L. Sawyers, Katherine A. Hoadley, Edwin Cuppen, Amnon Koren, Peter F. Arndt, David N. Louis, Lincoln D. Stein, William D. Foulkes, Paz Polak, Gad Getz

bioRxiv 517565; doi: https://doi.org/10.1101/517565 New Results
Short Tandem Repeats Information in TCGA is Statistically Biased by Amplification
Siddharth Jain, Bijan Mazaheri, Netanel Raviv, Jehoshua Bruck

bioRxiv 518878; doi: https://doi.org/10.1101/518878 New Results
A Note on Computing Interval Overlap Statistics
Shahab Sarmashghi, Vineet Bafna

bioRxiv 517987; doi: https://doi.org/10.1101/517987 New Results
Cancer Classification from Healthy DNA using Machine Learning
Siddharth Jain, Bijan Mazaheri, Netanel Raviv, Jehoshua Bruck

bioRxiv 517839; doi: https://doi.org/10.1101/517839 New Results
DOT1L suppresses nuclear RNAi originating from enhancer elements in Caenorhabditis elegans
Ruben Esse, Ekaterina Gushchanskaia, Avery Lord, Alla Grishok

bioRxiv 320465; doi: https://doi.org/10.1101/320465 New Results
Rapidly evolving protointrons in Saccharomyces genomes revealed by a hungry spliceosome
Jason Talkish, Haller Igel, Rhonda J Perriman, Lily Shiue, Sol Katzman, Elizabeth M Munding, Robert Shelansky, John Paul Donohue, Manuel Ares Jr.

bioRxiv 515197; doi: https://doi.org/10.1101/515197 New Results
ATRAID, a genetic factor that regulates the action of nitrogen-containing bisphosphonates on bone.
Lauren Surface, JiWoong Park, Sandeep Kumar, Damon Burrow, Cheng Lyu, Jinmei Li, Niki Song, Zhou Yu, Abbhirami Rajagopal, Yangjin Bae, Brendan Lee, Steven Mumm, Gabe Haller, Charles Gu, Jonathan Baker, Mahshid Mohseni, Melissa Sum, Margaret Huskey, Shenghui Duan, Vinieth Bijanki, Roberto Civitelli, Michael Gardner, Chris McAndrew, William Ricci, Christina Gurnett, Kathryn Diemer, Jan Carette, Malini Varadarajan, Thijn Brummelkamp, Kivanc Birsoy, David Sabatini, Tim Peterson

bioRxiv 338350; doi: https://doi.org/10.1101/338350 New Results
Kidney organoid reproducibility across multiple human iPSC lines and diminished off target cells after transplantation revealed by single cell transcriptomics
Ayshwarya Subramanian, Eriene-Heidi Sidhom, Maheswarareddy Emani, Nareh Sahakian, Katherine Vernon, Yiming Zhou, Maria Kost-Alimova, Astrid Weins, Michal Slyper, Julia Waldman, Danielle Dionne, Lan Nguyen, Jamie L Marshall, Orit Rozenblatt-Rosen, Aviv Regev, Anna Greka

bioRxiv 516807; doi: https://doi.org/10.1101/516807 New Results
Genetic and environmental perturbations drive modular transcriptome responses
Stephanie Mark, Joerg Weiss, Eesha Sharma, Ting Liu, Wei Wang, Julie Claycomb, Asher Cutter

bioRxiv 517235; doi: https://doi.org/10.1101/517235 New Results

Genomics

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