Genomics

Intra-individual methylomics detects the impact of early-life adversity
Shan Jiang, Noriko Kamei, Jessica L Bolton, Xinyi Ma, Hal S Stern, Tallie Z Baram, Ali Mortazavi

bioRxiv 440503; doi: https://doi.org/10.1101/440503 New Results
Population-scale proteome variation in human induced pluripotent stem cells
Bogdan Mirauta, Daniel D Seaton, Dalila Bensaddek, Alejandro Brenes, Marc Jan Bonder, Helena Kilpinen, HipSci consortium, Oliver Stegle, Angus Lamond

bioRxiv 439216; doi: https://doi.org/10.1101/439216 New Results
Genome-wide analyses supported by RNA-Seq reveal non-canonical splice sites in plant genomes
Boas Pucker, Samuel Fraser Brockington

bioRxiv 428318; doi: https://doi.org/10.1101/428318 New Results
New insights on human essential genes based on integrated analysis
Hebing Chen, Zhuo Zhang, Shuai Jiang, Ruijiang Li, Wanying Li, Chenghui Zhao, Hao Hong, Xin Huang, Hao Li, Xiaochen Bo

bioRxiv 260224; doi: https://doi.org/10.1101/260224 New Results
DNA methylation oscillation defines classes of enhancers
Emanuele Libertini, Rifat Hamoudi, Simon Heath, Lee Lancashire, Arcadio Rubio Garcia, Luigi Grassi, Kate Downes, Willem Ouwehand, Biola-Maria Javierre, Jonathan Cairns, Steven Wingett, Dirk Paul, Marta Gut, Ivo Gut, Joost Martens, Alexandr Ivliev, Hendrik Stunnenberg, Mattia Frontini, Mikhail Spivakov, Peter Fraser, Anthony Cutler, Chris Wallace, Stephan Beck

bioRxiv 262212; doi: https://doi.org/10.1101/262212 New Results
Modular modeling improves the predictions of genetic variant effects on splicing
Jun Cheng, Thi Yen Duong Nguyen, Kamil J Cygan, Muhammed Hasan Celik, William Fairbrother, Ziga Avsec, Julien Gagneur

bioRxiv 438986; doi: https://doi.org/10.1101/438986 New Results
Whole genome sequencing enables definitive diagnosis of Cystic Fibrosis and Primary Ciliary Dyskinesia
Jamie M Ellingford, Glenda Beaman, Kevin Webb, Christopher O'Callaghan, Robert A Hirst, The 100,000 Genomes Project, Graeme CM Black, William G Newman

bioRxiv 438838; doi: https://doi.org/10.1101/438838 New Results
Accurate characterization of expanded tandem repeat length and sequence through whole genome long-read sequencing on PromethION.
Arne De Roeck, Wouter De Coster, Liene Bossaerts, Rita Cacace, Tim De Pooter, Jasper Van Dongen, Svenn D'Hert, Peter De Rijk, Mojca Strazisar, Christine Van Broeckhoven, Kristel Sleegers

bioRxiv 439026; doi: https://doi.org/10.1101/439026 New Results
Managing the Spatial Covariance of Genetic Diversity in Niemann-Pick C1 Through Modulation of the Hsp70 Chaperone System
Chao Wang, Samantha M Scott, Darren M Hutt, Pei Zhao, Hao Shao, Jason E Gestwicki, William E Balch

bioRxiv 437764; doi: https://doi.org/10.1101/437764 New Results
gwasurvivr: an R package for genome wide survival analysis
Abbas A Rizvi, Ezgi Karaesmen, Martin Morgan, Leah Preus, Junke Wang, Theresa Hahn, Michael Sovic, Lara Sucheston-Campbell

bioRxiv 326033; doi: https://doi.org/10.1101/326033 New Results

Genomics

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