Genomics

Hi-C deconvolution of a human gut microbiome yields high-quality draft genomes and reveals plasmid-genome interactions.
Maximilian O. Press, Andrew H. Wiser, Zev N. Kronenberg, Kyle W. Langford, Migun Shakya, Chien-Chi Lo, Kathryn A. Mueller, Shawn T. Sullivan, Patrick S. G. Chain, Ivan Liachko

bioRxiv 198713; doi: https://doi.org/10.1101/198713 New Results
A unified web platform for network-based analyses of genomic data
Taibo Li, April Kim, Johnathan Mercer, Joseph Rosenbluh, Heiko Horn, Liraz Greenfeld, David An, Andrew Zimmer, Arthur Liberzon, Jon Bistline, Ted Natoli, Yang Li, Aviad Tsherniak, Rajiv Narayan, Aravind Subramanian, Ted Liefeld, Bang Wong, Dawn Thompson, Sarah Calvo, Steve Carr, Jesse Boehm, Jake Jaffe, Jill Mesirov, Nir Hacohen, Aviv Regev, Kasper Lage

bioRxiv 196303; doi: https://doi.org/10.1101/196303 New Results
Phenotype-specific information improves prediction of functional impact for noncoding variants
Corneliu A. Bodea, Adele A. Mitchell, Aaron G. Day-Williams, Heiko Runz, Shamil R. Sunyaev

bioRxiv 083642; doi: https://doi.org/10.1101/083642 New Results
Extensive Regulatory Changes in Genes Affecting Vocal and Facial Anatomy Separate Modern from Archaic Humans
David Gokhman, Lily Agranat-Tamir, Genevieve Housman, Raquel Garcia-Perez, Malka Nissim-Rafinia, Swapan Mallick, Maria Nieves-Colón, Heng Li, Songul Alpaslan-Roodenberg, Mario Novak, Hongcang Gu, Manuel Ferrando-Bernal, Pere Gelabert, Iddi Lipende, Ivanela Kondova, Ronald Bontrop, Ellen E. Quillen, Alexander Meissner, Anne C. Stone, Anne E. Pusey, Deus Mjungu, Leonid Kandel, Meir Liebergall, María E. Prada, Julio M. Vidal, Kay Prüfer, Johannes Krause, Benjamin Yakir, Svante Pääbo, Ron Pinhasi, Carles Lalueza-Fox, David Reich, Tomas Marques-Bonet, Eran Meshorer, Liran Carmel

bioRxiv 106955; doi: https://doi.org/10.1101/106955 New Results
Profiling and leveraging relatedness in a precision medicine cohort of 92,455 exomes
Jeffrey Staples, Evan K Maxwell, Nehal Gosalia, Claudia Gonzaga-Jauregui, Christopher Snyder, Alicia Hawes, John Penn, Ricardo Ulloa, Xiadong Bai, Alexander E Lopez, Cristopher V Van Hout, Colm O'Dushlaine, Tanya M Teslovich, Shane E McCarthy, Suganthi Balasubramanian, H Lester Kirchner, Joseph B Leader, Michael F Murray, David H Ledbetter, Alan R Shuldiner, George Yancoupolos, Frederick E Dewey, David J Carey, John D Overton, Aris Baras, Lukas Habegger, Jeffrey G Reid

bioRxiv 197889; doi: https://doi.org/10.1101/197889 New Results
Comparative analysis of the genomes of Stylophora pistillata and Acropora digitifera provides evidence for extensive differences between species of corals
Christian R Voolstra, Yong Li, Yi Jin Liew, Sebastian Baumgarten, Didier Zoccola, Jean-Francois Flot, Sylvie Tambutte, Denis Allemand, Manuel Aranda

bioRxiv 197830; doi: https://doi.org/10.1101/197830 New Results
RES complex is associated with intron definition and required for zebrafish early embryogenesis
Juan Fernandez, Miguel Moreno-Mateos, Andre Gohr, Shun Chan, Manuel Irimia, Antonio Giraldez

bioRxiv 197939; doi: https://doi.org/10.1101/197939 New Results
bigSCale: An Analytical Framework for Big-Scale Single-Cell Data
Giovanni Iacono, Elisabetta Mereu, Amy Guillaumet-Adkins, Roser Corominas, Ivon Cusco, Gustavo Rodriguez-Esteban, Marta Gut, Luis Alberto Perez-Jurado, Ivo Gut, Holger Heyn

bioRxiv 197244; doi: https://doi.org/10.1101/197244 New Results
Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics
Alvaro N. Barbeira, Scott P. Dickinson, Jason M. Torres, Rodrigo Bonazzola, Jiamao Zheng, Eric S. Torstenson, Heather E. Wheeler, Kaanan P. Shah, Todd Edwards, Tzintzuni Garcia, GTEx Consortium, Dan Nicolae, Nancy J. Cox, Hae Kyung Im

bioRxiv 045260; doi: https://doi.org/10.1101/045260 New Results
Development of an integrated genomic map for a threatened Caribbean coral (Orbicella faveolata)
Jacob Snelling, Katherine Dziedzic, Sarah Guermond, Eli Meyer

bioRxiv 183467; doi: https://doi.org/10.1101/183467 New Results

Genomics

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