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Genomics

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  • Genetic Influences on Brain Gene Expression in Rats Selected for Tameness and Aggression
    Henrike O. Heyne, Susann Lautenschläger, Ronald Nelson, François Besnier, Maxime Rotival, Alexander Cagan, Rimma Kozhemyakina, Irina Z. Plyusnina, Lyudmila Trut, Örjan Carlborg, Enrico Petretto, Leonid Kruglyak, Svante Pääbo, Torsten Schöneberg, Frank W. Albert
    bioRxiv 004234; doi: https://doi.org/10.1101/004234
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  • Whole Genome Bisulfite Sequencing of Cell Free DNA and its Cellular Contributors Uncovers Placenta Hypomethylated Domains
    Taylor J. Jensen, Sung K. Kim, Zhanyang Zhu, Christine Chin, Claudia Gebhard, Tim Lu, Cosmin Deciu, Dirk van den Boom, Mathias Ehrich
    bioRxiv 004101; doi: https://doi.org/10.1101/004101
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  • New whole genome de novo assemblies of three divergent strains of rice (O. sativa) documents novel gene space of aus and indica
    M.C. Schatz, L.G. Maron, J.C. Stein, Wences A. Hernandez, J. Gurtowski, E. Biggers, H. Lee, M. Kramer, E. Antoniou, E. Ghiban, M.H. Wright, J.H. Chia, D. Ware, S.R. McCouch, W.R. McCombie
    bioRxiv 003764; doi: https://doi.org/10.1101/003764
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  • Preparation of next-generation DNA sequencing libraries from ultra-low amounts of input DNA: Application to single-molecule, real-time (SMRT) sequencing on the Pacific Biosciences RS II
    Castle Raley, David Munroe, Kristie Jones, Yu-Chih Tsai, Yan Guo, Bao Tran, Sujatha Gowda, Jennifer L. Troyer, Daniel R Soppet, Claudia Stewart, Robert Stephens, Jack Chen, TF Skelly, Cheryl Heiner, Jonas Korlach, Dwight Nissley
    bioRxiv 003566; doi: https://doi.org/10.1101/003566
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  • Epigenetic Modifications are Associated with Inter-species Gene Expression Variation in Primates
    Xiang Zhou, Carolyn E. Cain, Marsha Myrthil, Noah Lewellen, Katelyn Michelini, Emily R. Davenport, Matthew Stephens, Jonathan K. Pritchard, Yoav Gilad
    bioRxiv 003467; doi: https://doi.org/10.1101/003467
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  • The disruption of trace element homeostasis due to aneuploidy as a unifying theme in the etiology of cancer
    Johannes Engelken, Matthias Altmeyer, Renty B. Franklin
    bioRxiv 002105; doi: https://doi.org/10.1101/002105
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  • Distinct structural transitions of chromatin topological domains coordinate hormone-induced gene regulation
    François Le Dily, Davide Baù, Andy Pohl, Guillermo Vicent, Daniel Soronellas, Giancarlo Castellano, François Serra, Roni H. G. Wright, Cecilia Ballare, Guillaume Filion, Marc A. Marti-Renom, Miguel Beato
    bioRxiv 003293; doi: https://doi.org/10.1101/003293
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  • Fast Principal Component Analysis of Large-Scale Genome-Wide Data
    Gad Abraham, Michael Inouye
    bioRxiv 002238; doi: https://doi.org/10.1101/002238
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  • Modeling the functional relationship network at the splice isoform level through heterogeneous data integration
    Hong-Dong Li, Rajasree Menon, Ridvan Eksi, Aysam Guerler, Yang Zhang, Gilbert S. Omenn, Yuanfang Guan
    bioRxiv 001719; doi: https://doi.org/10.1101/001719
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  • Characterization of directed differentiation by high-throughput single-cell RNA-Seq
    Magali Soumillon, Davide Cacchiarelli, Stefan Semrau, Alexander van Oudenaarden, Tarjei S. Mikkelsen
    bioRxiv 003236; doi: https://doi.org/10.1101/003236
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