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Genomics

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  • Model-directed generation of CRISPR-Cas13a guide RNAs designs artificial sequences that improve nucleic acid detection
    Sreekar Mantena, Priya P. Pillai, Brittany A. Petros, Nicole L. Welch, Cameron Myhrvold, Pardis C. Sabeti, Hayden C. Metsky
    bioRxiv 2023.09.20.557569; doi: https://doi.org/10.1101/2023.09.20.557569 New Results
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  • Massive-scale single-cell chromatin accessibility sequencing using combinatorial fluidic indexing
    Xuan Zhang, Alexandre P Marand, Haidong Yan, Robert J Schmitz
    bioRxiv 2023.09.17.558155; doi: https://doi.org/10.1101/2023.09.17.558155 New Results
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  • Cohesin mediated loop extrusion from active enhancers form chromatin jets in C. elegans
    Jun Kim, Sevinç Ercan
    bioRxiv 2023.09.18.558239; doi: https://doi.org/10.1101/2023.09.18.558239 New Results
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  • Single cell decoding of drug induced transcriptomic reprogramming in triple negative breast cancers
    Farhia Kabeer, Hoa Tran, Mirela Andronescu, Gurdeep Singh, Hakwoo Lee, Sohrab Salehi, Justina Biele, Jazmine Brimhall, David Gee, Viviana Cerda, Ciara O’Flanagan, Teresa Algara, Takako Kono, Sean Beatty, Elena Zaikova, Daniel Lai, Eric Lee, Richard Moore, Andrew J. Mungall, IMAXT Consortium, Marc J. Williams, Andrew Roth, Kieran R. Campbell, Sohrab P. Shah, Samuel Aparicio
    bioRxiv 2023.09.19.558329; doi: https://doi.org/10.1101/2023.09.19.558329 New Results
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  • Genomic context sensitizes regulatory elements to genetic disruption
    Raquel Ordoñez, Weimin Zhang, Gwen Ellis, Yinan Zhu, Hannah J. Ashe, André M. Ribeiro-dos-Santos, Ran Brosh, Emily Huang, Megan S. Hogan, Jef D. Boeke, Matthew T. Maurano
    bioRxiv 2023.07.02.547201; doi: https://doi.org/10.1101/2023.07.02.547201 New Results
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  • Structural and Functional Disparities within the Human Gut Virome in terms of Genome Topology and Representative Genome Selection
    Werner P Veldsman, Chao Yang, Zhenmiao Zhang, Yufen Huang, Lu Zhang
    bioRxiv 2023.09.18.558355; doi: https://doi.org/10.1101/2023.09.18.558355 New Results
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  • Opposing, spatially-determined epigenetic forces impose restrictions on stochastic olfactory receptor choice
    Elizaveta V. Bashkirova, Nell Klimpert, Kevin Monahan, Christine E. Campbell, Jason M. Osinski, Longzhi Tan, Ira Schieren, Ariel Pourmorady, Beka Stecky, Gilad Barnea, X. Sunnie Xie, Ishmail Abdus-Saboor, Benjamin Shykind, Bianca Jones-Marlin, Richard M. Gronostajski, Alexander Fleischmann, Stavros Lomvardas
    bioRxiv 2023.03.15.532726; doi: https://doi.org/10.1101/2023.03.15.532726 New Results
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  • Single-cell nascent RNA sequencing using click-chemistry unveils coordinated transcription
    Dig B. Mahat, Nathaniel D. Tippens, Jorge D. Martin-Rufino, Sean K. Waterton, Jiayu Fu, Sarah E. Blatt, Phillip A. Sharp
    bioRxiv 2023.09.15.558015; doi: https://doi.org/10.1101/2023.09.15.558015 New Results
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  • Telomere-to-telomere Schizosaccharomyces japonicus genome assembly reveals hitherto unknown genome features
    Graham J Etherington, Pei-Shang Wu, Snezhana Oliferenko, Frank Uhlmann, Conrad A. Nieduszynski
    bioRxiv 2023.09.04.556195; doi: https://doi.org/10.1101/2023.09.04.556195 New Results
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  • Phylogenetics, Epidemiology and Temporal Patterns of Dengue Virus type 1 in Araraquara, São Paulo State
    Caio dos Santos Souza, Giovana Santos Caleiro, Ingra Morales Claro, Jaqueline Goes de Jesus, Thaís Moura Coletti, Camila Alves Maia da Silva, Angela Aparecida Costa, Marta Inenami, Andreia C Ribeiro, Alvina Clara Felix, Anderson Vicente de Paula, Walter M Figueiredo, Expedito José de Albuquerque Luna, Ester Sabino, Camila Malta Romano
    bioRxiv 2023.09.18.558374; doi: https://doi.org/10.1101/2023.09.18.558374 New Results
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