Genomics

Model-directed generation of CRISPR-Cas13a guide RNAs designs artificial sequences that improve nucleic acid detection
Sreekar Mantena, Priya P. Pillai, Brittany A. Petros, Nicole L. Welch, Cameron Myhrvold, Pardis C. Sabeti, Hayden C. Metsky

bioRxiv 2023.09.20.557569; doi: https://doi.org/10.1101/2023.09.20.557569 New Results

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Massive-scale single-cell chromatin accessibility sequencing using combinatorial fluidic indexing
Xuan Zhang, Alexandre P Marand, Haidong Yan, Robert J Schmitz

bioRxiv 2023.09.17.558155; doi: https://doi.org/10.1101/2023.09.17.558155 New Results

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Cohesin mediated loop extrusion from active enhancers form chromatin jets in C. elegans
Jun Kim, Sevinç Ercan

bioRxiv 2023.09.18.558239; doi: https://doi.org/10.1101/2023.09.18.558239 New Results

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Single cell decoding of drug induced transcriptomic reprogramming in triple negative breast cancers
Farhia Kabeer, Hoa Tran, Mirela Andronescu, Gurdeep Singh, Hakwoo Lee, Sohrab Salehi, Justina Biele, Jazmine Brimhall, David Gee, Viviana Cerda, Ciara O’Flanagan, Teresa Algara, Takako Kono, Sean Beatty, Elena Zaikova, Daniel Lai, Eric Lee, Richard Moore, Andrew J. Mungall, IMAXT Consortium, Marc J. Williams, Andrew Roth, Kieran R. Campbell, Sohrab P. Shah, Samuel Aparicio

bioRxiv 2023.09.19.558329; doi: https://doi.org/10.1101/2023.09.19.558329 New Results

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Genomic context sensitizes regulatory elements to genetic disruption
Raquel Ordoñez, Weimin Zhang, Gwen Ellis, Yinan Zhu, Hannah J. Ashe, André M. Ribeiro-dos-Santos, Ran Brosh, Emily Huang, Megan S. Hogan, Jef D. Boeke, Matthew T. Maurano

bioRxiv 2023.07.02.547201; doi: https://doi.org/10.1101/2023.07.02.547201 New Results

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Structural and Functional Disparities within the Human Gut Virome in terms of Genome Topology and Representative Genome Selection
Werner P Veldsman, Chao Yang, Zhenmiao Zhang, Yufen Huang, Lu Zhang

bioRxiv 2023.09.18.558355; doi: https://doi.org/10.1101/2023.09.18.558355 New Results

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Opposing, spatially-determined epigenetic forces impose restrictions on stochastic olfactory receptor choice
Elizaveta V. Bashkirova, Nell Klimpert, Kevin Monahan, Christine E. Campbell, Jason M. Osinski, Longzhi Tan, Ira Schieren, Ariel Pourmorady, Beka Stecky, Gilad Barnea, X. Sunnie Xie, Ishmail Abdus-Saboor, Benjamin Shykind, Bianca Jones-Marlin, Richard M. Gronostajski, Alexander Fleischmann, Stavros Lomvardas

bioRxiv 2023.03.15.532726; doi: https://doi.org/10.1101/2023.03.15.532726 New Results

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Single-cell nascent RNA sequencing using click-chemistry unveils coordinated transcription
Dig B. Mahat, Nathaniel D. Tippens, Jorge D. Martin-Rufino, Sean K. Waterton, Jiayu Fu, Sarah E. Blatt, Phillip A. Sharp

bioRxiv 2023.09.15.558015; doi: https://doi.org/10.1101/2023.09.15.558015 New Results

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Telomere-to-telomere Schizosaccharomyces japonicus genome assembly reveals hitherto unknown genome features
Graham J Etherington, Pei-Shang Wu, Snezhana Oliferenko, Frank Uhlmann, Conrad A. Nieduszynski

bioRxiv 2023.09.04.556195; doi: https://doi.org/10.1101/2023.09.04.556195 New Results

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Phylogenetics, Epidemiology and Temporal Patterns of Dengue Virus type 1 in Araraquara, São Paulo State
Caio dos Santos Souza, Giovana Santos Caleiro, Ingra Morales Claro, Jaqueline Goes de Jesus, Thaís Moura Coletti, Camila Alves Maia da Silva, Angela Aparecida Costa, Marta Inenami, Andreia C Ribeiro, Alvina Clara Felix, Anderson Vicente de Paula, Walter M Figueiredo, Expedito José de Albuquerque Luna, Ester Sabino, Camila Malta Romano

bioRxiv 2023.09.18.558374; doi: https://doi.org/10.1101/2023.09.18.558374 New Results

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Genomics

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