Genomics

Global Genome Nucleotide Excision Repair is Organised into Domains Promoting Efficient DNA Repair in Chromatin
Shirong Yu, Katie Evans, Patrick van Eijk, Mark Bennett, Richard M. Webster, Matthew Leadbitter, Yumin Teng, Raymond Waters, Stephen P. Jackson, Simon H. Reed

bioRxiv 050807; doi: https://doi.org/10.1101/050807

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Promoter architecture and sex-specific gene expression in the microcrustacean Daphnia pulex revealed by large-scale profiling of 5′-mRNA ends
R. Taylor Raborn, Ken Spitze, Volker P. Brendel, Michael Lynch

bioRxiv 047894; doi: https://doi.org/10.1101/047894

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Whole genome sequencing identifies independent outbreaks of Shigellosis in 2010 and 2011 in La Pampa Province, Argentina
Isabel Chinen, Marcelo Galas, Ezequiel Tuduri, Maria Rosa Viñas, Carolina Carbonari, Anabella Della Gaspera, Daniela Nápoli, David M Aanensen, Silvia Argimón, Nicholas R Thomson, Darren Hughes, Stephen Baker, Caterina Guzmán-Verri, Matthew TG Holden, Alejandra M Abdala, Lucia P Alvarez, Beatriz Alvez, Rosana Barros, Shirley Budall, Constanza Campano, Luciana S Chamosa, Paul Cheddie, Daniel Cisterna, Denise De Belder, Milena Dropa, David Durand, Alan Elena, Gustavo Fontecha, Claudia Huber, Ana Paula Lemos, Luciano Melli, Roxana Elizabeth Paul, Lesly Suarez, Julian Torres Flores, Josefina Campos

bioRxiv 049940; doi: https://doi.org/10.1101/049940

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Copy number variants in the sheep genome detected using multiple approaches
Gemma M Jenkins, Michael E Goddard, Michael A Black, Rudiger Brauning, Benoit Auvray, Ken G Dodds, James W Kijas, Noelle Cockett, John C McEwan

bioRxiv 041475; doi: https://doi.org/10.1101/041475

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NGS-based assay for frequent newborn inherited diseases: from development to implementation
T. Simakova, A. Bragin, M. Zaytseva, C. Clemente, M. Lewicka, J.C. Machado, J.L. Costa, M. Hughes, C. Hertz-Fowler, N. Petrova, A. Polyakov, R. Zinchenko, E. Kondratyeva, A. Pavlov

bioRxiv 050419; doi: https://doi.org/10.1101/050419

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Recurrently deregulated lncRNAs associated with HCC tumorigenesis and metastasis revealed by genomic, epigenomic, and transcriptomic profiling in paired primary tumor and PVTT samples
Yang Yang, Lei Chen, Jin Gu, Hanshuo Zhang, Jiapei Yuan, Qiuyu Lian, Guishuai Lv, Siqi Wang, Yang Wu, Yu-Cheng T. Yang, Dongfang Wang, Yang Liu, Jing Tang, Guijuan Luo, Yang Li, Long Hu, Xinbao Sun, Dong Wang, Mingzhou Guo, Qiaoran Xi, Jianzhong Xi, Hongyang Wang, Michael Q. Zhang, Zhi John Lu

bioRxiv 050377; doi: https://doi.org/10.1101/050377

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Population Genetic Analysis of the DARC Locus (Duffy) Reveals Adaptation from Standing Variation Associated with Malaria Resistance in Humans
Kimberly F. McManus, Angela Taravella, Brenna Henn, Carlos D. Bustamante, Martin Sikora, Omar E. Cornejo

bioRxiv 050096; doi: https://doi.org/10.1101/050096

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AAV-mediated CRISPR/Cas gene editing of retinal cells in vivo
Sandy SC Hung, Vicki Chrysostomou, Fan Li, Jeremiah KH Lim, Jiang-Hui Wang, Joseph E Powell, Leilei Tu, Maciej Daniszewski, Camden Lo, Raymond C Wong, Jonathan G Crowston, Alice Pébay, Anna E King, Bang V Bui, Guei-Sheung Liu, Alex W Hewitt

bioRxiv 039156; doi: https://doi.org/10.1101/039156

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Fast, scalable and accurate differential expression analysis for single cells
Debarka Sengupta, Nirmala Arul Rayan, Michelle Lim, Bing Lim, Shyam Prabhakar

bioRxiv 049734; doi: https://doi.org/10.1101/049734

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Widespread shortening of 3’ untranslated regions and increased exon inclusion are evolutionarily conserved features of innate immune responses to infection
Athma A. Pai, Golshid Baharian, Ariane Pagé Sabourin, Jessica F. Brinkworth, Yohann Nédélec, Joseph W. Foley, Jean-Christophe Grenier, Katherine J. Siddle, Anne Dumaine, Vania Yotova, Zachary P. Johnson, Robert E. Lanford, Christopher B. Burge, Luis B. Barreiro

bioRxiv 026831; doi: https://doi.org/10.1101/026831

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Genomics

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