Immunology

Early exposure to broadly neutralizing antibodies may trigger a dynamical switch from progressive disease to lasting control of SHIV infection
Rajat Desikan, Rubesh Raja, Narendra M Dixit

bioRxiv 548727; doi: https://doi.org/10.1101/548727 New Results

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In silico characterization of mechanisms positioning costimulatory and checkpoint complexes in immune synapses
Anastasios Siokis, Philippe A Robert, Philippos Demetriou, Audun Kvalvaag, Salvatore Valvo, Viveka Mayya, Michael L Dustin, Michael Meyer-Hermann

bioRxiv 2020.01.16.908723; doi: https://doi.org/10.1101/2020.01.16.908723 New Results

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Complement C5a impairs phagosomal maturation in the neutrophil through phosphoproteomic remodelling.
Alexander JT Wood, Arlette M Vassallo, Marie-Helene Ruchard-Sparagano, Jonathan Scott, Carmelo Zinnato, Carmen Gonzalez-Tejedo, Kamal Kishore, Clive D'Santos, A John Simpson, David Menon, Charlotte Summers, Edwin R Chilvers, Klaus Okkenhaug, Andrew Conway Morris

bioRxiv 2020.01.17.907618; doi: https://doi.org/10.1101/2020.01.17.907618 New Results

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Morphological profiling of human T and NK lymphocytes identifies actin-mediated control of the immunological synapse
Yolla German, Loan Vulliard, Aude Rubio, Kaan Boztug, Audrey Ferrand, Joerg Menche, Loic Dupre

bioRxiv 2020.01.17.910091; doi: https://doi.org/10.1101/2020.01.17.910091 New Results

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Multiplexed Single-cell Metabolic Profiles Organize the Spectrum of Human Cytotoxic T Cells
Felix J Hartmann, Dunja Mrdjen, Erin McCaffrey, David R Glass, Noah F Greenwald, Anusha Bharadwaj, Zumana Khair, Alex Baranski, Reema Baskar, Michael Angelo, Sean C Bendall

bioRxiv 2020.01.17.909796; doi: https://doi.org/10.1101/2020.01.17.909796 New Results

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Type-1 IFN primed monocytes in pathogenesis of idiopathic pulmonary fibrosis
Ling-Pei Ho, Emily Fraser, Laura Denney, Karl Blirando, Chaitanya Vuppusetty, Agne Antanaviciute, Yuejuan Zheng, Emmanouela Repapi, Valentina Iotchkova, Stephen Taylor, Neil Ashley, Victoria St Noble, Rachel Hoyles, Rachel Benamore, Colin Clelland, Joseph Rastrick, Clare S Hardman, Nasullah Alham, Rachel Rigby, Jan Rehwinkel

bioRxiv 2020.01.16.908749; doi: https://doi.org/10.1101/2020.01.16.908749 New Results

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Human MAIT cell cytolytic effector proteins synergize to overcome carbapenem resistance in Escherichia coli
Caroline Boulouis, Wan Rong Sia, Muhammad Yaaseen Gulam, Jocelyn Qi Min Teo, Thanh Kha Phan, Jeffrey Y. W Mak, David P. Fairlie, Ivan K. H. Poon, Tse Hsien Koh, Peter Bergman, Lin-Fa Wang, Andrea Lay Hoon Kwa, Johan K. Sandberg, Edwin Leeansyah

bioRxiv 2020.01.16.908806; doi: https://doi.org/10.1101/2020.01.16.908806 New Results

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Crystal structure of the giant panda MHC class I complex: first insights into the viral peptide presentation profile in the bear family
Hongyu Yuan, Lizhen Ma, Lijie Zhang, Xiaoying Li, Chun Xia

bioRxiv 2020.01.15.908608; doi: https://doi.org/10.1101/2020.01.15.908608 New Results

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Nivolumab and Ipilimumab in Metastatic Melanoma Are Associated with Distinct Immune Landscape Changes and Response-Associated Immunophenotypes
David M Woods, Andressa S Laino, Aidan F Winters, Jason M Alexandre, Vinay Rao, Santi S Adavani, Jeffrey S Weber, Pratip K Chattopadhyay

bioRxiv 2020.01.13.905430; doi: https://doi.org/10.1101/2020.01.13.905430 New Results

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Dynamic metabolic reprogramming in dendritic cells: an early response to influenza infection that is essential for effector function
Svetlana Rezinciuc, Lavanya Bezavada, Azadeh Bahadoran, Susu Duan, Ruoning Wang, Daniel Lopez-Ferrer, Erika E. Zink, David Finklestein, Douglas R. Green, Ljiljana Pasa-Tolic, Paul G. Thomas, Heather S. Smallwood

bioRxiv 2020.01.14.906826; doi: https://doi.org/10.1101/2020.01.14.906826 New Results

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Immunology

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