Immunology

Complex Autoinflammatory Syndrome Unveils Fundamental Principles of JAK1 Transcriptional and Biochemical Function
Conor Gruber, Jorg Calis, Sofija Buta, Gilad Evrony, Jerome Martin, Skyler Uhl, Rachel Caron, Lauren Jarchin, David Dunkin, Robert Phelps, Bryn Webb, Jeffrey Saland, Miriam Merad, Jordan Orange, Emily Mace, Brad Rosenberg, Bruce Gelb, Dusan Bogunovic

bioRxiv 807669; doi: https://doi.org/10.1101/807669 New Results

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The Development, Function, and Plasticity of the Immune Macroenvironment in Cancer
Breanna M. Allen, Kamir J. Hiam, Cassandra E. Burnett, Anthony Venida, Rachel DeBarge, Yaron Carmi, Matthew H. Spitzer

bioRxiv 805473; doi: https://doi.org/10.1101/805473 New Results

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Identification of scavenger receptor B1 as the airway microfold cell receptor for Mycobacterium tuberculosis
Haaris S. Khan, Vidhya R. Nair, Cody R. Ruhl, Samuel Alvarez-Arguedas, Jorge L. Galvan Resendiz, Luis H. Franco, Linzhang Huang, Philip W. Shaul, Ron B. Mitchell, Michael U. Shiloh

bioRxiv 807222; doi: https://doi.org/10.1101/807222 New Results

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Lymph node follicle formation and vaccination responses reconstituted in vitro in a human Organ Chip
Girija Goyal, Bruce Bausk, Pranav Prabhala, Liangxia Xie, Danielle Curran, Jaclyn Long, Limor Cohen, Oren Levy, Rachelle Prantil-Baun, David R. Walt, Donald E. Ingber

bioRxiv 806505; doi: https://doi.org/10.1101/806505 New Results

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An optimized workflow for single-cell transcriptomics and repertoire profiling of purified lymphocytes from clinical samples
Richa Hanamsagar, Timothy Reizis, Mathew Chamberlain, Robert Marcus, Frank O. Nestle, Emanuele de Rinaldis, Virginia Savova

bioRxiv 803031; doi: https://doi.org/10.1101/803031 New Results

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Persistent DNA Hyper-methylation Dampens Host Anti-Mycobacterial Immunity
Andrew R. DiNardo, Kimal Rajapakshe, Tomoki Nishiguchi, Godwin Mtetwa, Qiniso Dlamini, Jaqueline Kahari, Sanjana Mahapatra, Alexander Kay, Gugu Maphalala, Emily Mace, Sandra L. Grimm, George Makedonas, Jeffrey D Cirillo, Mihai G. Netea, Reinout van Crevel, Cristian Coarfa, Anna M. Mandalakas

bioRxiv 805457; doi: https://doi.org/10.1101/805457 New Results

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Gut microbiota differently contributes to intestinal immune phenotype and systemic autoimmune progression in female and male lupus-prone mice
Benjamin M. Johnson, Marie-Claude Gaudreau, Radhika Gudi, Robert Brown, Gary Gilkeson, Chenthamarakshan Vasu

bioRxiv 787440; doi: https://doi.org/10.1101/787440 New Results

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IL2 enhances ex-vivo expanded regulatory T cell persistence after adoptive transfer
Scott N Furlan, Karnail Singh, Christina Lopez, Victor Tkachev, Daniel Hunt, James Hibbard, Kayla M Betz, Bruce R. Blazar, Cole Trapnell, Leslie S Kean

bioRxiv 805531; doi: https://doi.org/10.1101/805531 New Results

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Intracellular Neutralization of Ricin Toxin by Single Domain Antibodies Targeting the Active Site Pocket
Michael J. Rudolph, Timothy F. Czajka, Simon A. Davis, Chi My Thi Nguyen, Xiao-ping Li, Nilgun E. Tumer, David J. Vance, Nicholas J. Mantis

bioRxiv 805754; doi: https://doi.org/10.1101/805754 New Results

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The use of CRISPR for variant specificity in the genetic diagnosis of primary immunodeficiency disease (PID)
Tiffeney Mann, Amy Smith, Sarah Spencer, Alasdair Russell, James Thaventhiran

bioRxiv 804732; doi: https://doi.org/10.1101/804732 New Results

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Immunology

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