Immunology

A novel strategy for single-cell metabolic analysis highlights dynamic changes in immune subpopulations
Patricia J. Ahl, Richard A. Hopkins, Wen Wei Xiang, Bijin Au, Nivashini Kaliaperumal, Anna-Marie Fairhurst, John E. Connolly

bioRxiv 2020.01.21.914663; doi: https://doi.org/10.1101/2020.01.21.914663 New Results

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Human immune system variation during one year
Tadepally Lakshmikanth, Sayyed Auwn Muhammad, Axel Olin, Yang Chen, Jaromir Mikes, Linn Fagerberg, Anders Gummesson, Göran Bergström, Mathias Uhlen, Petter Brodin

bioRxiv 2020.01.22.915025; doi: https://doi.org/10.1101/2020.01.22.915025 New Results

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Construction of Nanobody Library in Mammalian Cells by Linear-double-stranded DNA Based AND Gate Genetic Circuit
Chunze Zhang, Xin Tong, Shuai Li

bioRxiv 2020.01.21.912907; doi: https://doi.org/10.1101/2020.01.21.912907 New Results

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Bcl6 Preserves the Suppressive Function of Regulatory T Cells during Tumorigenesis
Yiding Li, Zhiming Wang, Huayu Lin, Lisha Wang, Xiangyu Chen, Qiao Liu, Qianfei Zuo, Jianjun Hu, Haoqiang Wang, Junyi Guo, Luoyingzi Xie, Jianfang Tang, Zhirong Li, Li Hu, Lilin Ye, Qizhao Huang, Lifan Xu

bioRxiv 2020.01.21.914812; doi: https://doi.org/10.1101/2020.01.21.914812 New Results

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Single-cell metabolic analysis by mass cytometry reveals distinct transitional states of CD8 T cell differentiation
Lauren S. Levine, Kamir J. Hiam, Diana M. Marquez, Iliana Tenvooren, Diana C. Contreras, Jeffrey C. Rathmell, Matthew H. Spitzer

bioRxiv 2020.01.21.911545; doi: https://doi.org/10.1101/2020.01.21.911545 New Results

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Identification of novel, clinically correlated autoantigens in the monogenic autoimmune syndrome APS1 by PhIP-Seq
Sara E. Vazquez, Elise M. N. Ferré, David W. Scheel, Sara Sunshine, Brenda Miao, Caleigh Mandel-Brehm, Zoe Quandt, Alice Y. Chan, Mickie Cheng, Michael S. German, Michail S. Lionakis, Joseph L. DeRisi, Mark S. Anderson

bioRxiv 2020.01.20.913186; doi: https://doi.org/10.1101/2020.01.20.913186 New Results

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Poor Quality Vβ Recombination Signal Sequences Enforce TCRβ Allelic Exclusion by Limiting the Frequency of Vβ Recombination
Glendon S. Wu, Katherine S. Yang-Iott, Morgann A. Reed, Katharina E. Hayer, Kyutae D. Lee, Craig H. Bassing

bioRxiv 2020.01.20.913046; doi: https://doi.org/10.1101/2020.01.20.913046 New Results

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Lung type II alveolar epithelial cells collaborate with CCR2⁺ inflammatory monocytes in host defense against an acute vaccinia infection in the lungs
Ning Yang, Joseph M. Luna, Peihong Dai, Yi Wang, Charles M. Rice, Liang Deng

bioRxiv 2020.01.20.910927; doi: https://doi.org/10.1101/2020.01.20.910927 New Results

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Bacillus subtilis spore induces efficient generation of memory T cells via ICAM-1 expression on dendritic cells
Lulu Huang, Jian Lin, Yuchen Li, Penghao Zhang, Qinghua Yu, Qian Yang

bioRxiv 2020.01.20.912584; doi: https://doi.org/10.1101/2020.01.20.912584 New Results

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Naïve CD8 T cell IFNγ responses to a vacuolar antigen are regulated by an inflammasome-independent NLRP3 pathway and Toxoplasma gondii ROP5
Angel K. Kongsomboonvech, Felipe Rodriguez, Anh L. Diep, Brandon M. Justice, Brayan E. Castallanos, Ana Camejo, Debanjan Mukhopadhyay, Gregory A. Taylor, Masahiro Yamamoto, Jeroen P.J. Saeij, Michael L. Reese, Kirk D.C. Jensen

bioRxiv 2020.01.20.912568; doi: https://doi.org/10.1101/2020.01.20.912568 New Results

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Immunology

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