Immunology

Targeting CSF-1 ameliorates experimental autoimmune encephalomyelitis by depleting inflammatory monocytes and microglia in the central nervous system without affecting quiescent microglia.
Daniel Hwang, Larissa Lumi Watanabe Ishiwaka, Alexandra Boehm, Ziver Sahin, Giacomo Casella, Soohwa Jang, Maryamsadat Seyedsadr, Michael V Gonzalez, James P Garifallou, Hakon Hakonarson, Guang-Xian Zhang, Abdolmohamad Rostami, Bogoljub Ciric

bioRxiv 2020.10.23.352534; doi: https://doi.org/10.1101/2020.10.23.352534 New Results

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Oral immunization of broilers with chitosan nano-encapsulated extracellular and cell wall proteins of necrotic enteritis-induced Clostridium perfringens
Nour Muinis Ramadan, Gabriel O Akerele, Sankar Renu, Gourapura Renukaradhya, Ramesh Selvaraj

bioRxiv 2020.10.23.351817; doi: https://doi.org/10.1101/2020.10.23.351817 New Results

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The specific features of the developing T cell compartment of the neonatal lung are a determinant of respiratory syncytial virus immunopathogenesis
Thomas Demoulins, Melanie Bruegger, Beatrice Zumhehr, Blandina Oliveira Esteves, Kemal Mehinagic, Amal Fahmi, Loic Borcard, Adriano Taddeo, Horst Posthaus, Charaf Benarafa, Nicolas Ruggli, Marco P Alves

bioRxiv 2020.08.14.250829; doi: https://doi.org/10.1101/2020.08.14.250829 New Results

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Single cell RNA-seq reveals immunosuppressive gastric stem-like cancer cells as a poor prognostic factor
Hong Kai Lee, Kok Siong Ang, Marion Chevrier, Michelle Goh, Jingjing Ling, Vivien Koh, Xiaomeng Zhang, Jia Chi Tan, Nicole Lee, Sergio Erdal Irac, Ze Ming Lim, Josephine Lum, Alicia Tay, Charles Antoine Dutertre, Carolyn Tang, Calista Wong, Mai Chan Lau, Chun Jye Lim, Samuel Wen Jin Chuah, Sherlly Lim, Joe Poh Sheng Yeong, Valerie Chew, Anis Larbi, Amit Singhal, Michael Poidinger, Matthew Chau Hsien Ng, Shanshan Wu Howland, Patrick Tan, Florent Ginhoux, Jimmy So, Wei Peng Yong, Jinmiao Chen

bioRxiv 2020.10.23.351726; doi: https://doi.org/10.1101/2020.10.23.351726 New Results

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Integration, exploration, and analysis of high-dimensional single-cell cytometry data using Spectre
Thomas Myles Ashhurst, Felix Marsh-Wakefield, Givanna Haryono Putri, Alanna Gabrielle Spiteri, Diana Shinko, Mark Norman Read, Adrian Lloyd Smith, Nicholas Jonathan Cole King

bioRxiv 2020.10.22.349563; doi: https://doi.org/10.1101/2020.10.22.349563 New Results

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Mapping the Antibody Repertoires in Ferrets with Repeated Influenza A/H3 Infections: Is Original Antigenic Sin Really "Sinful"?
Tal Einav, Martina Kosikova, Peter Radvak, Yuan-Chia Kuo, Hyung Joon Kwon, Hang Xie

bioRxiv 2020.10.22.351338; doi: https://doi.org/10.1101/2020.10.22.351338 New Results

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mRNA based SARS-CoV-2 vaccine candidate CVnCoV induces high levels of virus neutralizing antibodies and mediates protection in rodents
Susanne Rauch, Nicole Roth, Kim Schwendt, Mariola Fotin-Mleczek, Stefan O. Mueller, Benjamin Petsch

bioRxiv 2020.10.23.351775; doi: https://doi.org/10.1101/2020.10.23.351775 New Results

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Single-cell secretion analysis reveals a dual role for IL-10 in restraining and resolving the TLR4-induced inflammatory response
Amanda F Alexander, Hannah Forbes, Kathryn Miller-Jensen

bioRxiv 2020.10.22.351254; doi: https://doi.org/10.1101/2020.10.22.351254 New Results

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Tolerogenic Dendritic Cells Shape a Transmissible Gut Microbiota that Protects from Metabolic Diseases
Emelyne Lécuyer, Tiphaine Le Roy, Aurélie Gestin, Amélie Lacombe, Catherine Philippe, Maharajah Ponnaiah, Jean-Baptiste Huré, Magali Fradet, Farid Ichou, Samira Boudebbouze, Thierry Huby, Emmanuel Gautier, Moez Rhimi, Emmanuelle Maguin, Nathalie Kapel, Philippe Gérard, Nicolas Venteclef, Michèle Garlatti, Benoit Chassaing, Philippe Lesnik

bioRxiv 2020.10.22.350033; doi: https://doi.org/10.1101/2020.10.22.350033 New Results

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Adenosine diphosphate contributes to wound healing in diabetic mice through P2Y₁ and P2Y₁₂ receptors activation
Paula A. Borges, Ingrid Waclawiak, Janaína L. Georgii, Janaína F. Barros, Vanderlei S. Fraga-Junior, Felipe S. Lemos, Thaís Russo-Abrahão, Elvira M. Saraiva, Christina M. Takiya, Robson Coutinho-Silva, Carmen Penido, Claudia Mermelstein, José R. Meyer-Fernandes, Fábio B. Canto, Josiane S. Neves, Paulo A. Melo, Claudio Canetti, Claudia F. Benjamim

bioRxiv 2020.10.22.350785; doi: https://doi.org/10.1101/2020.10.22.350785 New Results

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Immunology

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