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Immunology

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  • Immune sensing of food allergens promotes aversive behaviour
    Esther B. Florsheim, Nathaniel D. Bachtel, Jaime Cullen, Bruna G. C. Lima, Mahdieh Godazgar, Cuiling Zhang, Fernando Carvalho, Gregory Gautier, Pierre Launay, Andrew Wang, Marcelo O. Dietrich, Ruslan Medzhitov
    bioRxiv 2023.01.19.524823; doi: https://doi.org/10.1101/2023.01.19.524823 New Results
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  • Damage-induced pyroptosis drives endogenous thymic regeneration via induction of Foxn1 by purinergic receptor activation
    Sinéad Kinsella, Cindy A. Evandy, Kirsten Cooper, Antonella Cardinale, Lorenzo Iovino, Paul deRoos, Kayla S. Hopwo, Colton W. Smith, David Granadier, Lucas B. Sullivan, Enrico Velardi, Jarrod A. Dudakov
    bioRxiv 2023.01.19.524800; doi: https://doi.org/10.1101/2023.01.19.524800 New Results
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  • ARPC5 deficiency leads to severe early onset systemic inflammation and early mortality
    Elena Sindram, Andrés Caballero-Oteyza, Naoko Kogata, Shaina Huang, Zahra Alizadeh, Laura Gamez-Diaz, Mohammad Reza Fazlollhi, Xiao Peng, Bodo Grimbacher, Michael Way, Michele Proietti
    bioRxiv 2023.01.19.524688; doi: https://doi.org/10.1101/2023.01.19.524688 New Results
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  • Landscape of IGH germline genes of Chiroptera and the pattern of Rhinolophus affinis bat IGH CDR3 repertoire
    Long Ma, Longyu Liu, Jun Li, Hao Zhou, Jiaping Xiao, Qingqing Ma, Xinsheng Yao
    bioRxiv 2023.01.20.524863; doi: https://doi.org/10.1101/2023.01.20.524863 New Results
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  • Antimicrobial mitochondrial reactive oxygen species induction by lung epithelial metabolic reprogramming
    Yongxing Wang, Vikram V. Kulkarni, Jezreel Pantaleón García, Miguel M. Leiva-Juárez, David L. Goldblatt, Fahad Gulraiz, Jichao Chen, Sri Ramya Donepudi, Philip L. Lorenzi, Hao Wang, Lee-Jun Wong, Michael J. Tuvim, Scott E. Evans
    bioRxiv 2023.01.19.524841; doi: https://doi.org/10.1101/2023.01.19.524841 New Results
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  • Inflammatory CD4/CD8 double positive human T cells arise from reactive CD8 T cells and are sufficient to mediate GVHD pathology
    Nicholas J. Hess, David P. Turicek, Jeremiah Riendeau, Sean J. McIlwain, Emmanuel Contreras Guzman, Kalyan Nadiminti, Amy Hudson, Natalie S. Callander, Melissa C. Skala, Jenny E. Gumperz, Peiman Hematti, Christian M. Capitini
    bioRxiv 2022.01.11.475845; doi: https://doi.org/10.1101/2022.01.11.475845 New Results
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  • Gut-associated lymphoid tissue attrition associates with response to anti-α4β7 therapy in ulcerative colitis
    Pablo Canales-Herrerias, Mathieu Uzzan, Akihiro Seki, Rafael S. Czepielewski, Bram Verstockt, Alexandra Livanos, Fiona Raso, Alexandra Dunn, Daniel Dai, Andrew Wang, Zainab Al-taie, Jerome Martin, Huaibin M. Ko, Minami Tokuyama, Michael Tankelevich, Hadar Meringer, Francesca Cossarini, Divya Jha, Azra Krek, John D. Paulsen, M. Zuber Nakadar, Joshua Wong, Emma C. Erlich, Emily J. Onufer, Beth A. Helmink, Keshav Sharma, Adam Rosenstein, Grace Chung, Travis Dawson, Julius Juarez, Vijay Yajnik, Andrea Cerutti, Jeremiah Faith, Mayte Suarez-Farinas, Carmen Argmann, Francesca Petralia, Gwendalyn J. Randolph, Alexandros D. Polydorides, Andrea Reboldi, Jean Frederic Colombel, Saurabh Mehandru
    bioRxiv 2023.01.19.524731; doi: https://doi.org/10.1101/2023.01.19.524731 New Results
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  • Phage-specific immune responses impair efficacy of phage therapy targeting VRE in a murine model
    Julia D. Berkson, Garrison B. Allen, Alyxandria M. Schubert, Kristin E. Dunbar, Michael P. Coryell, Rosa L. Sava, Yamei Gao, Claire E. Wate, Jessica L. Hastie, Sally K. Zimmermann, Paul E. Carlson Jr.
    bioRxiv 2023.01.19.523600; doi: https://doi.org/10.1101/2023.01.19.523600 New Results
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  • Recognition determinants of broad and potent HIV-1 neutralization by an affinity matured antibody from a pediatric elite-neutralizer
    Sanjeev Kumar, Swarandeep Singh, Arnab Chatterjee, Prashant Bajpai, Shaifali Sharma, Sanket Katpara, Rakesh Lodha, Somnath Dutta, Kalpana Luthra
    bioRxiv 2023.01.19.524673; doi: https://doi.org/10.1101/2023.01.19.524673 New Results
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  • T helper cells exhibit a dynamic and reversible 3’UTR landscape
    Denis Seyres, Oliver Gorka, Ralf Schmidt, Romina Marone, Mihaela Zavolan, Lukas T. Jeker
    bioRxiv 2023.01.19.523753; doi: https://doi.org/10.1101/2023.01.19.523753 New Results
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