Immunology

A Polymorphic Residue That Attenuates the Antiviral Potential of Interferon Lambda 4 in Hominid Lineages
Connor G. G. Bamford, Elihu Aranday-Cortes, Inès Cordeiro Filipe, Swathi Sukumar, Daniel Mair, Ana da Silva Filipe, Juan L. Mendoza, K. Christopher Garcia, Shaohua Fan, Sarah A. Tishkoff, John McLauchlan

bioRxiv 214825; doi: https://doi.org/10.1101/214825

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Autoreactive T cells preferentially drive differentiation of non-responsive memory B cells at the expense of germinal center maintenance
Rajiv W Jain, Kate A Parham, Yodit Tesfagiorgis, Heather C Craig, Emiliano Romanchik, Steven M Kerfoot

bioRxiv 287789; doi: https://doi.org/10.1101/287789

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Glycosylation-dependent modulation of the lL-2 signaling axis determines Th17 differentiation and IL-10 production
Leona Gabryšová, Elizabeth H. Mann, Lydia Bradley, James I. MacRae, Charlotte Whicher, Catherine M. Hawrylowicz, Dimitrios Anastasiou, Anne O’Garra

bioRxiv 287920; doi: https://doi.org/10.1101/287920

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MAIT cells contribute to protection against lethal influenza infection in vivo
Bonnie van Wilgenburg, Liyen Loh, Zhenjun Chen, Troi J Pediongco, Huimeng Wang, Mai Shi, Zhe Zhao, Marios Koutsakos, Simone Nüssing, Sneha Sant, Zhongfang Wang, Criselle D’Souza, Catarina F Almeida, Lyudmila Kostenko, Sidonia BG Eckle, Bronwyn S Meehan, Dale I Godfrey, Patrick C Reading, Alexandra J Corbett, James McCluskey, Paul Klenerman, Katherine Kedzierska, Timothy SC Hinks

bioRxiv 247205; doi: https://doi.org/10.1101/247205

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Reference-based annotation of single cell transcriptomes identifies a profibrotic macrophage niche after tissue injury
Dvir Aran, Agnieszka P. Looney, Leqian Liu, Valerie Fong, Austin Hsu, Paul J. Wolters, Adam Abate, Atul J. Butte, Mallar Bhattacharya

bioRxiv 284604; doi: https://doi.org/10.1101/284604

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Synthetic standards combined with error and bias correction improves the accuracy and quantitative resolution of antibody repertoire sequencing in human naïve and memory B cells
Simon Friedensohn, John M. Lindner, Vanessa Cornacchione, Mariavittoria Iazeolla, Enkelejda Miho, Andreas Zingg, Simon Meng, Elisabetta Traggiai, Sai T. Reddy

bioRxiv 284810; doi: https://doi.org/10.1101/284810

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High dimensional analyses of cells dissociated from cryopreserved synovial tissue
Laura T. Donlin, Deepak A. Rao, Kevin Wei, Kamil Slowikowski, Mandy J. McGeachy, Jason D. Turner, Nida Meednu, Fumitaka Mizoguchi, Maria Gutierrez-Arcelus, David J. Lieb, Joshua Keegan, Kaylin Muskat, Joshua Hillman, Cristina Rozo, Edd Ricker, Thomas M. Eisenhaure, Shuqiang Li, Edward P. Browne, Adam Chicoine, Danielle Sutherby, Akiko Noma, Accelerating Medicines Partnership: RA/SLE Network, Chad Nusbaum, Stephen Kelly, Alessandra B. Pernis, Lionel B. Ivashkiv, Susan M. Goodman, William H. Robinson, Paul J. Utz, James A. Lederer, Ellen M. Gravallese, Brendan F. Boyce, Nir Hacohen, Costantino Pitzalis, Peter K. Gregersen, Gary S. Firestein, Soumya Raychaudhuri, Larry W. Moreland, V. Michael Holers, Vivian P. Bykerk, Andrew Filer, David L. Boyle, Michael B. Brenner, Jennifer H. Anolik

bioRxiv 284844; doi: https://doi.org/10.1101/284844

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A constitutively expressed antifungal peptide protects Tenebrio molitor during a natural infection by the entomopathogenic fungus Beauveria bassiana
Sevasti Maistrou, Véronique Paris, Annette B. Jensen, Jens Rolff, Nicolai V. Meyling, Caroline Zanchi

bioRxiv 284778; doi: https://doi.org/10.1101/284778

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The expansion in lymphoid organs of IL-4⁺ BATF+ T follicular helper cells is linked to IgG4 class switching in vivo
Takashi Maehara, Hamid Mattoo, Vinay S. Mahajan, Samuel J.H. Murphy, Grace J. Yuen, Noriko Ishiguro, Miho Ohta, Masafumi Moriyama, Takako Saeki, Hidetaka Yamamoto, Masaki Yamauchi, Joe Daccache, Tamotsu Kiyoshima, Seiji Nakamura, John H. Stone, Shiv Pillai

bioRxiv 284737; doi: https://doi.org/10.1101/284737

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Elucidating the activation mechanisms for bifurcation of regulatory and effector T cell fates by multidimensional single cell analysis
Alla Bradley, Tetsuo Hashimoto, Masahiro Ono

bioRxiv 280818; doi: https://doi.org/10.1101/280818

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Immunology

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