Immunology

IL-33 regulates gene expression in intestinal epithelial cells independently of its nuclear localization
Zhengxiang He, Lili Chen, Glaucia C. Furtado, Sergio A. Lira

bioRxiv 291039; doi: https://doi.org/10.1101/291039

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Hemolysin liberates bacterial outer membrane vesicles for cytosolic lipopolysaccharide sensing
Shouwen Chen, Dahai Yang, Ying Wen, Zhiwei Jiang, Lingzhi Zhang, Jiatiao Jiang, Yaozhen Chen, Tianjian Hu, Qiyao Wang, Yuanxing Zhang, Qin Liu

bioRxiv 290445; doi: https://doi.org/10.1101/290445

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Cullin1 represses systematic inflammasome activation by binding and catalyzing NLRP3 ubiquitination
Pin Wan, Qi Zhang, Weiyong Liu, Yaling Jia, Tianci Wang, Wenbiao Wang, Pan Pan, Ge Yang, Qi Xiang, Siyu Huang, Qingyu Yang, Wei Zhang, Fang Liu, Kailang Wu, Yingle Liu, Jianguo Wu

bioRxiv 289637; doi: https://doi.org/10.1101/289637

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A hypermorphic Nfkbid allele represents an Idd7 locus gene contributing to impaired thymic deletion of autoreactive diabetogenic CD8⁺ T-cells in NOD mice
Maximiliano Presa, Jeremy J. Racine, Jennifer R. Dwyer, Deanna J. Lamont, Jeremy J. Ratiu, Vishal Kumar Sarsani, Yi-Guang Chen, Aron Geurts, Ingo Schmitz, Timothy Stearns, Jennifer Allocco, Harold D. Chapman, David V. Serreze

bioRxiv 249094; doi: https://doi.org/10.1101/249094

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A Polymorphic Residue That Attenuates the Antiviral Potential of Interferon Lambda 4 in Hominid Lineages
Connor G. G. Bamford, Elihu Aranday-Cortes, Inès Cordeiro Filipe, Swathi Sukumar, Daniel Mair, Ana da Silva Filipe, Juan L. Mendoza, K. Christopher Garcia, Shaohua Fan, Sarah A. Tishkoff, John McLauchlan

bioRxiv 214825; doi: https://doi.org/10.1101/214825

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Autoreactive T cells preferentially drive differentiation of non-responsive memory B cells at the expense of germinal center maintenance
Rajiv W Jain, Kate A Parham, Yodit Tesfagiorgis, Heather C Craig, Emiliano Romanchik, Steven M Kerfoot

bioRxiv 287789; doi: https://doi.org/10.1101/287789

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Glycosylation-dependent modulation of the lL-2 signaling axis determines Th17 differentiation and IL-10 production
Leona Gabryšová, Elizabeth H. Mann, Lydia Bradley, James I. MacRae, Charlotte Whicher, Catherine M. Hawrylowicz, Dimitrios Anastasiou, Anne O’Garra

bioRxiv 287920; doi: https://doi.org/10.1101/287920

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MAIT cells contribute to protection against lethal influenza infection in vivo
Bonnie van Wilgenburg, Liyen Loh, Zhenjun Chen, Troi J Pediongco, Huimeng Wang, Mai Shi, Zhe Zhao, Marios Koutsakos, Simone Nüssing, Sneha Sant, Zhongfang Wang, Criselle D’Souza, Catarina F Almeida, Lyudmila Kostenko, Sidonia BG Eckle, Bronwyn S Meehan, Dale I Godfrey, Patrick C Reading, Alexandra J Corbett, James McCluskey, Paul Klenerman, Katherine Kedzierska, Timothy SC Hinks

bioRxiv 247205; doi: https://doi.org/10.1101/247205

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Reference-based annotation of single cell transcriptomes identifies a profibrotic macrophage niche after tissue injury
Dvir Aran, Agnieszka P. Looney, Leqian Liu, Valerie Fong, Austin Hsu, Paul J. Wolters, Adam Abate, Atul J. Butte, Mallar Bhattacharya

bioRxiv 284604; doi: https://doi.org/10.1101/284604

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Synthetic standards combined with error and bias correction improves the accuracy and quantitative resolution of antibody repertoire sequencing in human naïve and memory B cells
Simon Friedensohn, John M. Lindner, Vanessa Cornacchione, Mariavittoria Iazeolla, Enkelejda Miho, Andreas Zingg, Simon Meng, Elisabetta Traggiai, Sai T. Reddy

bioRxiv 284810; doi: https://doi.org/10.1101/284810

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Immunology

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