Immunology

Corynebacterium diphtheriae causes keratinocyte-intrinsic ribotoxic stress and NLRP1 inflammasome activation in a model of cutaneous diphtheria
Kim S. ROBINSON, Gee Ann TOH, Muhammad Jasrie FIRDAUS, Khek Chian THAM, Pritisha ROZARIO, Chrissie LIM, Ying Xiu TOH, Zhi Heng LAU, Sophie Charlotte BINDER, Jacob MAYER, Carine BONNARD, Florian I. SCHMIDT, John E. A. COMMON, Franklin L. ZHONG

bioRxiv 2023.01.16.524188; doi: https://doi.org/10.1101/2023.01.16.524188 New Results

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EEF2-inactivating toxins engage the NLRP1 inflammasome and promote epithelial barrier disruption upon Pseudomonas infection
Miriam Pinilla, Raoul Mazars, Romain Vergé, Leana Gorse, Karin Santoni, Kim Samirah Robinson, Gee Ann Toh, Laure Prouvensier, Stephen Adonai LeonIcaza, Audrey Hessel, David Péricat, Marlène Murris, Anthony Henras, Julien Buyck, Céline Cougoule, Emmanuel Ravet, Franklin L. Zhong, Rémi Planès, Etienne Meunier

bioRxiv 2023.01.16.524164; doi: https://doi.org/10.1101/2023.01.16.524164 New Results

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Intranasal mRNA-LNP vaccination protects hamsters from SARS-CoV-2 infection
Gabriela Baldeon Vaca, Michelle Meyer, Ana Cadete, Chiaowen Joyce Hsiao, Anne Golding, Albert Jeon, Eric Jacquinet, Emily Azcue, Chenxia Monica Guan, Xavier Sanchez-Felix, Colette A. Pietzsch, Chad E. Mire, Matthew A. Hyde, Margaret E. Comeaux, Julie M. Williams, Jean C. Sung, Andrea Carfi, Darin K. Edwards, Alexander Bukreyev, Kapil Bahl

bioRxiv 2023.01.11.523616; doi: https://doi.org/10.1101/2023.01.11.523616 New Results

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Redistribution and activation of CD16^brightCD56^dim NK cell subset to fight against Omicron subvariant BA.2 after COVID-19 vaccination
Yang Liu, Huiyun Peng, Tianxin Xiang, Fei Xu, Yuhuan Jiang, Lipeng Zhong, Yanqi Peng, Aiping Le, Wei Zhang

bioRxiv 2023.01.13.524025; doi: https://doi.org/10.1101/2023.01.13.524025 New Results

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Maintained imbalance of triglycerides, apolipoproteins, energy metabolites and cytokines in long-term COVID-19 syndrome (LTCS) patients
Georgy Berezhnoy, Rosi Bissinger, Anna Liu, Claire Cannet, Hartmut Schaefer, Katharina Kienzle, Michael Bitzer, Helene Häberle, Siri Göpel, Christoph Trautwein, Yogesh Singh

bioRxiv 2023.01.13.523998; doi: https://doi.org/10.1101/2023.01.13.523998 New Results

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Therapeutic and vaccine-induced cross-reactive antibodies with effector function against emerging Omicron variants
Amin Addetia, Luca Piccoli, James Brett Case, Young-Jun Park, Martina Beltramello, Barbara Guarino, Ha Dang, Dora Pinto, Suzanne M. Scheaffer, Kaitlin Sprouse, Jessica Bassi, Chiara Silacci- Fregni, Francesco Muoio, Marco Dini, Lucia Vincenzetti, Rima Acosta, Daisy Johnson, Sambhavi Subramanian, Christian Saliba, Martina Giurdanella, Gloria Lombardo, Giada Leoni, Katja Culap, Carley McAlister, Anushka Rajesh, Exequiel Dellota Jr., Elisabetta Cameroni, Bradley Whitener, Olivier Giannini, Alessandro Ceschi, Paolo Ferrari, Alessandra Franzetti-Pellanda, Maira Biggiogero, Christian Garzoni, Stephanie Zappi, Luca Bernasconi, Min Jeong Kim, Gretja Schnell, Nadine Czudnochowski, Nicholas Franko, Jennifer K. Logue, Courtney Yoshiyama, Cameron Stewart, Helen Chu, Michael A. Schmid, Lisa A. Purcell, Gyorgy Snell, Antonio Lanzavecchia, Michael S. Diamond, Davide Corti, David Veesler

bioRxiv 2023.01.17.523798; doi: https://doi.org/10.1101/2023.01.17.523798 New Results

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3-D deconvolution of human skin immune architecture with Multiplex Annotated Tissue Imaging System (MANTIS)
Manon Scholaert, Raissa Houmadi, Jeremy Martin, Nadine Serhan, Marie Tauber, Emilie Braun, Lilian Basso, Eric Merle, Pascal Descargues, Manuelle Viguier, Cécile Lesort, Benoît Chaput, Jean Kanitakis, Denis Jullien, Cristina Bulai Livideanu, Laurence Lamant, Emeline Pagès, Nicolas Gaudenzio

bioRxiv 2023.01.13.523748; doi: https://doi.org/10.1101/2023.01.13.523748 New Results

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Mass cytometry identifies characteristic immune cell subsets in bronchoalveolar lavage fluid from interstitial lung diseases
Kentaro Hata, Toyoshi Yanagihara, Keisuke Matsubara, Kazufumi Kunimura, Kunihiro Suzuki, Kazuya Tsubouchi, Daisuke Eto, Hiroyuki Ando, Maki Uehara, Satoshi Ikegame, Yoshihiro Baba, Yoshinori Fukui, Isamu Okamoto

bioRxiv 2023.01.12.523734; doi: https://doi.org/10.1101/2023.01.12.523734 New Results

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NF-κB-Inducing Kinase (NIK) Governs the Mitochondrial Respiratory Capacity, Differentiation, and Inflammatory Status of Innate Immune Cells
Justin N. Keeney, Ashley Winters, Raquel Sitcheran, A. Phillip West

bioRxiv 2022.08.06.503047; doi: https://doi.org/10.1101/2022.08.06.503047 New Results

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Control of enhancer activation in the type I interferon response by the histone demethylase Kdm4d / JMJD2d
Rohit Chandwani, Terry C. Fang, Scott Dewell, Alexander Tarakhovsky

bioRxiv 2023.01.14.524033; doi: https://doi.org/10.1101/2023.01.14.524033 New Results

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Immunology

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