Immunology

Interferon-induced lysosomal membrane permeabilization and death cause cDC1-deserts in tumors
E. Aerakis, A. Chatzigeorgiou, M. Alvanou, M. Matthaiakaki-Panagiotaki, I. Angelidis, D. Koumadorakis, A. Galaras, P. Hatzis, D. Kerdidani, M. Makridakis, A. Vlachou, B. Malissen, S. Henri, M. Merad, M. Tsoumakidou

bioRxiv 2022.03.14.484263; doi: https://doi.org/10.1101/2022.03.14.484263 New Results

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New insights into the Germline Genes and CDR3 Repertoire of the TCRβ chain in Chiroptera
Hao Zhou, Jun Li, Dewei Zhou, Yingjie Wu, Xingliang Wang, Jiang Zhou, Qingqing Ma, Xinsheng Yao, Long Ma

bioRxiv 2022.12.05.519110; doi: https://doi.org/10.1101/2022.12.05.519110 New Results

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Bcl-2 supports survival and metabolic fitness of quiescent tissue-resident ILC3
James I. King, Felipe Melo-Gonzalez, Bert Malengier-Devlies, Roser Tachó-Piñot, Marlene S Magalhaes, Suzanne H. Hodge, Xavier Romero Ros, Rebecca Gentek, Matthew R. Hepworth

bioRxiv 2023.02.27.528945; doi: https://doi.org/10.1101/2023.02.27.528945 New Results

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Engineered Immunogens to Expose Conserved Epitopes Targeted by Broad Coronavirus Antibodies
Brenda Kapingidza, Daniel J. Marston, Caitlin Harris, Daniel Wrapp, Kaitlyn Winters, Brianna Rhodes, Pranay Vure, Christopher W. Woods, Elizabeth A. Petzold, Emmanuel B Walter, Rob Parks, Maggie Barr, Qi Yin, Derek W. Cain, Kevin Wiehe, Kevin O. Saunders, Barton F. Haynes, Mihai L. Azoitei

bioRxiv 2023.02.27.530277; doi: https://doi.org/10.1101/2023.02.27.530277 New Results

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Signaling Node at TSC2 S1365 Potently Regulates T-Cell Differentiation and Improves Adoptive Cellular Cancer Therapy
Chirag H Patel, Yi Dong, Brittany L Dunkerly-Eyring, Jiayu Wen, Mark J Ranek, Laura M Bartle, Daniel B Henderson, Jason Sagert, David A Kass, Jonathan D Powell

bioRxiv 2022.11.30.518569; doi: https://doi.org/10.1101/2022.11.30.518569 New Results

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SICKO: Systematic Imaging of Caenorhabditis Killing Organisms
Luis S Espejo, Samuel Freitas, Vanessa Silbar, Leah Chang, Jonah Balsa, Angelo Antenor, Hope Dang, Destiny DeNicola, George L Sutphin

bioRxiv 2023.02.17.529009; doi: https://doi.org/10.1101/2023.02.17.529009 New Results

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Single-cell analysis of CX3CR1⁺ cells reveal a pathogenic role for BIRC5⁺ myeloid proliferating cells driven by Staphylococcus aureus leukotoxins
Denis G. Loredan, Joseph C. Devlin, Keenan A. Lacey, Nina Howard, Ze Chen, Erin E. Zwack, Jian-Da Lin, Kelly V. Ruggles, Kamal M. Khanna, Victor J. Torres, P’ng Loke

bioRxiv 2023.02.27.529760; doi: https://doi.org/10.1101/2023.02.27.529760 New Results

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Therapeutic and vaccine-induced cross-reactive antibodies with effector function against emerging Omicron variants
Amin Addetia, Luca Piccoli, James Brett Case, Young-Jun Park, Martina Beltramello, Barbara Guarino, Ha Dang, Dora Pinto, Suzanne M. Scheaffer, Kaitlin Sprouse, Jessica Bassi, Chiara Silacci-Fregni, Francesco Muoio, Marco Dini, Lucia Vincenzetti, Rima Acosta, Daisy Johnson, Sambhavi Subramanian, Christian Saliba, Martina Giurdanella, Gloria Lombardo, Giada Leoni, Katja Culap, Carley McAlister, Anushka Rajesh, Exequiel Dellota Jr., Jiayi Zhou, Nisar Farhat, Dana Bohan, Julia Noack, Florian A. Lempp, Elisabetta Cameroni, Bradley Whitener, Olivier Giannini, Alessandro Ceschi, Paolo Ferrari, Alessandra Franzetti-Pellanda, Maira Biggiogero, Christian Garzoni, Stephanie Zappi, Luca Bernasconi, Min Jeong Kim, Gretja Schnell, Nadine Czudnochowski, Nicholas Franko, Jennifer K. Logue, Courtney Yoshiyama, Cameron Stewart, Helen Chu, Michael A. Schmid, Lisa A. Purcell, Gyorgy Snell, Antonio Lanzavecchia, Michael S. Diamond, Davide Corti, David Veesler

bioRxiv 2023.01.17.523798; doi: https://doi.org/10.1101/2023.01.17.523798 New Results

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FOXP3⁺ regulatory T cells use heparanase to access IL-2 bound to ECM in inflamed tissues
Hunter A. Martinez, Ievgen Koliesnik, Gernot Kaber, Jacqueline K. Reid, Nadine Nagy, Graham Barlow, Ben A. Falk, Carlos O. Medina, Aviv Hargil, Israel Vlodavsky, Jin-Ping Li, Magdiel Pérez-Cruz, Sai-Wen Tang, Everett H. Meyer, Lucile E. Wrenshall, James D. Lord, K. Christopher Garcia, Theo D. Palmer, Lawrence Steinman, Gerald T. Nepom, Thomas N. Wight, Paul L. Bollyky, Hedwich F. Kuipers

bioRxiv 2023.02.26.529772; doi: https://doi.org/10.1101/2023.02.26.529772 New Results

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Active maintenance of CD8⁺ T cell naïvety through regulation of global genome architecture
Brendan E. Russ, Kirril Tsyganov, Sara Quon, Bingfei Yu, Jasmine Li, Jason K. C. Lee, Moshe Olshansky, Zhaohren He, Paul F. Harrison, Adele Barugahare, Michael See, Simone Nussing, Alison E. Morey, Vibha A. Udupa, Taylah .J Bennett, Axel Kallies, Cornelis Murre, Phillipe Collas, David Powell, Ananda W. Goldrath, Stephen J. Turner

bioRxiv 2023.02.26.530139; doi: https://doi.org/10.1101/2023.02.26.530139 New Results

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Immunology

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