Immunology

Prenatal maternal infection promotes maternal microchimeric cells to alter infection risk in male offspring
Brittany Jimena, Daniel Kazimierczyk, Simon Kazimierczyk, Haley Moya, Eva Shin, Li Li, Parimal Korgaonkar, Caryn Porter, Brian Seed, Bobby J. Cherayil, Nitya Jain

bioRxiv 2025.01.17.633596; doi: https://doi.org/10.1101/2025.01.17.633596 New Results

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Recruiting ESCRT to single-chain heterotrimer peptide-MHCI releases antigen-presenting vesicles that stimulate T cells selectively
Blade A. Olson, Kathryn E. Huey-Tubman, Zhiyuan Mao, Magnus A. G. Hoffmann, Richard M. Murray, Stephen L. Mayo

bioRxiv 2025.01.17.633600; doi: https://doi.org/10.1101/2025.01.17.633600 New Results

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Super-omics and PCAS reveal rheumatoid arthritis as a tumor-like disease
Lanlan Xiao, Nadire Aishan, Siwei Ju, Fengchao Zhao, Xiaoxi Ouyang, Dazhi Chen, Weiqian Chen, Jie Xie, Danhua Zhu, Junchi Zhang, Lingyun Sun, Yimin Li, Dan Zhou, Qingqing Hu, Jinzhi Wu, Qingna Meng, Jichun Zhou, Danyi Xu, Jingyi Yu, Junyu Liang, Yangjun Cai, Minmin Zhang, Yanlin He, Zeyu Sun, Linbo Wang, Jin Lin, Feiyang Ji

bioRxiv 2025.01.17.633562; doi: https://doi.org/10.1101/2025.01.17.633562 New Results

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Macrophages restrict tumor permissiveness to immune infiltration by controlling local collagen topography through a Tcf4-Collagen3 fibrotic axis
Zoé Fusilier, Franck Simon, Isabel Calvente, Lou Crestey, Alexandra Clément, Mathilde Mathieu, Roude Jean-Marie, Florence Piastra-Facon, Jeyani George Clément, Enola Lumineau, Mattia Tonani, Valeria Manriquez, Livia Lacerda, Perrine de Villemagne, Eliane Piaggio, Vincent Semetey, Sylvie Coscoy, Emanuele Martini, Giorgio Scita, Jean-Christophe Gelly, Johanna Ivaska, Hervé Isambert, Christel Goudot, Paolo Pierobon, Ana-Maria Lennon-Duménil, Hélène D. Moreau

bioRxiv 2025.01.17.633527; doi: https://doi.org/10.1101/2025.01.17.633527 New Results

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Global transcriptome analysis identifies nicotinamide metabolism to play key roles in IFN-γ and nitric oxide modulated responses
Avik Chattopadhyay, Sai Shyam, Shreyasee Das, Dipankar Nandi

bioRxiv 2025.01.17.633516; doi: https://doi.org/10.1101/2025.01.17.633516 New Results

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Multiparametric optimization of human primary B-cell cultures using Design of Experiments
Anne Bruun Rovsing, Kenneth Green, Lisbeth Jensen, Ian Helstrup Nielsen, Jacob Giehm Mikkelsen, Søren E. Degn

bioRxiv 2025.01.16.633474; doi: https://doi.org/10.1101/2025.01.16.633474 New Results

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Comparison candidate Tick-borne encephalitis virus vaccines based on mRNA, adenovirus serotype 25 and chimera of YFV vaccine strain
Nadezhda A. Kuznetsova, Vladimir A. Gushchin, Elizaveta V. Marchuk, Andrei E. Siniavin, Denis A. Kleymenov, Maria Nikiforova, Olga V. Zubkova, Olga Popova, Irina V. Vavilova, Tatiana A. Ozharovskaia, Elena P. Mazunina, Evgeniia N. Bykonia, Egor Y. Bogdanov, Anastasia N. Zolotar, Elena V. Shidlovskaya, Evgeny V. Usachev, Olga V. Usacheva, Alexey G. Shatalov, Vladimir I. Zlobin, Denis Y. Logunov, Alexander L. Gintsburg

bioRxiv 2025.01.16.633390; doi: https://doi.org/10.1101/2025.01.16.633390 New Results

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Heterogeneity of anti-Caspr2 antibodies: specificity and pathogenicity
Julia Su, Rohan Gupta, Scott Van Hoof, Jakob Kreye, Harald Prüss, Benjamin Spielman, Lior Brimberg, Bruce T. Volpe, Patricio T. Huerta, Betty Diamond

bioRxiv 2025.01.16.633238; doi: https://doi.org/10.1101/2025.01.16.633238 New Results

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Pretransplant targeting of TNFRSF25 and CD25 stimulates recipient Tregs in target tissues ameliorating GVHD post-HSCT
Duneia McManus, Sabrina N. Copsel, Brent J. Pffeifer, Dietlinde Wolf, Henry Barreras, Symon Ma, Ali Khodor, Seitaro Komai, Marina Burgos da Silva, Hajar Hazime, Miguel Gallardo, Marcel RM van den Brink, Maria T. Abreu, Geoffrey R. Hill, Victor L. Perez, Robert B. Levy

bioRxiv 2025.01.16.633453; doi: https://doi.org/10.1101/2025.01.16.633453 New Results

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A nonhuman primate model mirrors human congenital cytomegalovirus infection and reveals a spectrum of vertical transmission outcomes
Tabitha Manuel, Matilda Moström, Chelsea M. Crooks, Angel Davalos, Richard Barfield, Elizabeth Scheef, Savannah Kendall, Cecily C. Midkiff, Lesli Sprehe, Macey Trexler, Francis Boquet, Monica Shroyer, Victoria Danner, Lara Doyle-Myers, Carolyn Weinbaum, Anne Mirza, Stephen Lammi, Claire Otero, Marissa R. Lee, Layne W. Rogers, Joshua Granek, Kouros Owzar, Daniel Malouli, Klaus Früh, Timothy Kowalik, Cliburn Chan, Sallie R. Permar, Robert V. Blair, Amitinder Kaur

bioRxiv 2025.01.16.633406; doi: https://doi.org/10.1101/2025.01.16.633406 New Results

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Immunology

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