Immunology

In vivo CRISPR screening identifies Fli1 as a transcriptional safeguard that restrains effector CD8 T cell differentiation during infection and cancer
Zeyu Chen, Eri Arai, Omar Khan, Zhen Zhang, Shin Foong Ngiow, Yuan He, Hua Huang, Sasikanth Manne, Zhendong Cao, Amy E. Baxter, Zhangying Cai, Elizabeth Freilich, Mohammed A. Ali, Josephine R. Giles, Jennifer E. Wu, Allison R. Greenplate, Makoto Kurachi, Kito Nzingha, Viktoriya Ekshyyan, Zhuoyu Wen, Nancy A. Speck, Alexis Battle, Shelley L. Berger, E. John Wherry, Junwei Shi

bioRxiv 2020.05.20.087379; doi: https://doi.org/10.1101/2020.05.20.087379 New Results

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Deep sequencing of B cell receptor repertoires from COVID-19 patients reveals strong convergent immune signatures
Jacob D. Galson, Sebastian Schaetzle, Rachael J. M. Bashford-Rogers, Matthew I. J. Raybould, Aleksandr Kovaltsuk, Gavin J. Kilpatrick, Ralph Minter, Donna K. Finch, Jorge Dias, Louisa James, Gavin Thomas, Wing-Yiu Jason Lee, Jason Betley, Olivia Cavlan, Alex Leech, Charlotte M. Deane, Joan Seoane, Carlos Caldas, Dan Pennington, Paul Pfeffer, Jane Osbourn

bioRxiv 2020.05.20.106294; doi: https://doi.org/10.1101/2020.05.20.106294 New Results

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CD8+ T cell cross-reactivity against SARS-CoV-2 conferred by other coronavirus strains and influenza virus
Chloe H. Lee, Mariana Pereira Pinho, Paul Buckley, Isaac Woodhouse, Graham Ogg, Alison Simmons, Giorgio Napolitani, Hashem Koohy

bioRxiv 2020.05.20.107292; doi: https://doi.org/10.1101/2020.05.20.107292 New Results

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Clinical And Analytical Performance Of An Automated Serological Test That Identifies S1/S2 Neutralizing IgG In Covid-19 Patients Semiquantitatively
Fabrizio Bonelli, Antonella Sarasini, Claudia Zierold, Mariella Calleri, Alice Bonetti, Chiara Vismara, Frank Blocki, Luca Pallavicini, Alberto Chinali, Daniela Campisi, Elena Percivalle, Anna Pia DiNapoli, Carlo Federico Perno, Fausto Baldanti

bioRxiv 2020.05.19.105445; doi: https://doi.org/10.1101/2020.05.19.105445 New Results

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Tiger team: a panel of human neutralizing mAbs targeting SARS-CoV-2 spike at multiple epitopes
Tal Noy-Porat, Efi Makdasi, Ron Alcalay, Adva Mechaly, Yinon Levi, Adi Bercovich-Kinori, Ayelet Zauberman, Hadas Tamir, Yfat Yahalom-Ronen, Ma’ayan Israeli, Eyal Epstein, Hagit Achdout, Sharon Melamed, Theodor Chitlaru, Shay Weiss, Eldar Peretz, Osnat Rosen, Nir Paran, Shmuel Yitzhaki, Shmuel C. Shapira, Tomer Israely, Ohad Mazor, Ronit Rosenfeld

bioRxiv 2020.05.20.106609; doi: https://doi.org/10.1101/2020.05.20.106609 New Results

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PU.1 enforces quiescence and limits hematopoietic stem cell expansion during inflammatory stress
James S. Chavez, Jennifer L. Rabe, Dirk Loeffler, Kelly C. Higa, Giovanny Hernandez, Taylor S. Mills, Nouraiz Ahmed, Rachel L. Gessner, Zhonghe Ke, Beau M. Idler, Hyun Min Kim, Jason R. Myers, Brett M. Stevens, Craig T. Jordan, Hideaki Nakajima, John Ashton, Robert S. Welner, Timm Schroeder, James DeGregori, Eric M. Pietras

bioRxiv 2020.05.18.102830; doi: https://doi.org/10.1101/2020.05.18.102830 New Results

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Isolation of and Characterization of Neutralizing Antibodies to Covid-19 from a Large Human Naïve scFv Phage Display Library
Andy Q. Yuan, Likun Zhao, Lili Bai, Qingwu Meng, Zhenguo Wen, Yanhu Li, Daqing Guo, Shanshan Zhen, Xiaojun Chen, Ji Yang, Xiaoying Xue

bioRxiv 2020.05.19.104281; doi: https://doi.org/10.1101/2020.05.19.104281 New Results

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Estimating seroprevalence with imperfect serological tests: exploiting cutoff-free approaches
Judith A Bouman, Sebastian Bonhoeffer, Roland R Regoes

bioRxiv 2020.04.29.068999; doi: https://doi.org/10.1101/2020.04.29.068999 New Results

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Th2-like T-follicular helper cells promote functional antibody production during Plasmodium falciparum infection
Jo-Anne Chan, Fabian de Labastida Rivera, Jessica Loughland, Jessica A Engel, Hyun Jae Lee, Arya SheelaNair, Bruce D Wines, Fiona H Amante, Lachlan Webb, Pamela Mukhopadhyay, Ann-Marie Patch, P. Mark Hogarth, James G Beeson, James S McCarthy, Ashraful Haque, Christian R Engwerda, Michelle J Boyle

bioRxiv 2020.05.18.101048; doi: https://doi.org/10.1101/2020.05.18.101048 New Results

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Controlling the SARS-CoV-2 Spike Glycoprotein Conformation
Rory Henderson, Robert J Edwards, Katayoun Mansouri, Katarzyna Janowska, Victoria Stalls, Sophie Gobeil, Megan Kopp, Allen Hsu, Mario Borgnia, Rob Parks, Barton F. Haynes, Priyamvada Acharya

bioRxiv 2020.05.18.102087; doi: https://doi.org/10.1101/2020.05.18.102087 New Results

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Immunology

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