Immunology

Glycosylation-dependent modulation of the lL-2 signaling axis determines Th17 differentiation and IL-10 production
Leona Gabrysova, Elizabeth H Mann, Lydia Bradley, James I MacRae, Charlotte Whicher, Catherine M Hawrylowicz, Dimitrios Anastasiou, Anne O'Garra

bioRxiv 287920; doi: https://doi.org/10.1101/287920 New Results
MAIT cells contribute to protection against lethal influenza infection in vivo
Bonnie van Wilgenburg, Liyen Loh, Zhenjun Chen, Troi J Pediongco, Huimeng Wang, Mai Shi, Zhe Zhao, Marios Koutsakos, Simone Nussing, Sneha Sant, Zhongfang Wang, Criselle D'Souza, Catarina F Almeida, Lyudmila Kostenko, Sidonia BG Eckle, Bronwyn S Meehan, Dale I Godfrey, Patrick C Reading, Alexandra J Corbett, James McCluskey, Paul Klenerman, Katherine Kedzierska, Timothy Hinks

bioRxiv 247205; doi: https://doi.org/10.1101/247205 New Results
Reference-based annotation of single-cell transcriptomes identifies a profibrotic macrophage niche after tissue injury
Dvir Aran, Agnieszka P. Looney, Leqian Liu, Valerie Fong, Austin Hsu, Paul J. Wolters, Adam Abate, Atul J. Butte, Mallar Bhattacharya

bioRxiv 284604; doi: https://doi.org/10.1101/284604 New Results
Synthetic standards combined with error and bias correction improves the accuracy and quantitative resolution of antibody repertoire sequencing in human naive and memory B cells
Simon Friedensohn, John M Lindner, Vanessa Cornacchione, Mariavittoria Iazeolla, Enkelejda Miho, Andreas Zingg, Simon Meng, Elisabetta Traggiai, Sai T Reddy

bioRxiv 284810; doi: https://doi.org/10.1101/284810 New Results
Footprints of antigen processing boost MHC class II natural ligand binding predictions
Carolina M Barra, Bruno Alvarez, Massimo Andreatta, Soren Buus, Morten Nielsen

bioRxiv 285767; doi: https://doi.org/10.1101/285767 New Results
High dimensional analyses of cells dissociated from cryopreserved synovial tissue
Laura T. Donlin, Deepak A. Rao, Kevin Wei, Kamil Slowikowski, Mandy J. McGeachy, Jason D. Turner, Nida Meednu, Fumitaka Mizoguchi, Maria Gutierrez-Arcelus, David J. Lieb, Joshua Keegan, Kaylin Muskat, Joshua Hillman, Cristina Rozo, Edd Ricker, Thomas M. Eisenhaure, Shuqiang Li, Edward P. Browne, Adam Chicoine, Danielle Sutherby, Akiko Noma, Chad Nusbaum, Stephen Kelly, Alessandra B. Pernis, Lionel B. Ivashkiv, Susan M. Goodman, William H. Robinson, Paul J. Utz, James A. Lederer, Ellen M. Gravallese, Brendan F. Boyce, Nir Hacohen, Costantino Pitzalis, Peter K. Gregersen, Gary S. Firestein, Soumya Raychaudhuri, Larry W. Moreland, Michael Holers, Vivian P. Bykerk, Andrew Filer, David L. Boyle, Michael B. Brenner, Jennifer H. Anolik

bioRxiv 284844; doi: https://doi.org/10.1101/284844 New Results
A constitutively expressed antifungal peptide protects Tenebrio molitor during a natural infection by the entomopathogenic fungus Beauveria bassiana.
Sevasti Maistrou, Véronique Paris, Annette Bruun Jensen, Jens Rolff, Nicolai Vitt Meyling, Caroline Zanchi

bioRxiv 284778; doi: https://doi.org/10.1101/284778 New Results
The expansion in lymphoid organs of IL-4+ BATF+ T follicular helper cells is linked to IgG4 class switching in vivo
Shiv Pillai, John Stone, Seiji Nakamura, Tamotsu Kiyoshima, Joe Daccache, Masaki Yamauchi, Hidetaka Yamamoto, Takako Saeki, Masafumi Moriyama, Miho Ohta, Noriko Ishiguro, Grace J Yuen, Samuel L. Murphy, Vinay Mahajan, Hamid Mattoo, Takashi Maehara

bioRxiv 284737; doi: https://doi.org/10.1101/284737 New Results
Elucidating the activation mechanisms for bifurcation of regulatory and effector T cell fates by multidimensional single cell analysis
Alla Bradley, Tetsuo Hashimoto, Masahiro Ono

bioRxiv 280818; doi: https://doi.org/10.1101/280818 New Results
PI3Kδ hyper-activation promotes the development of B cells that exacerbate Streptococcus pneumoniae infection in an antibody-independent manner
Anne-Katrien Stark, Anita Chandra, Krishnendu Chakraborty, Rafeah Alam, Valentina Carbonaro, Jonathan Clark, Srividya Sriskantharajah, Glyn Bradley, Alex G Richter, Edward Banham-Hall, Menna R Clatworthy, Sergey Nejentsev, J Nicole Hamblin, Edith M Hessel, Alison M Condliffe, Klaus Okkenhaug

bioRxiv 280651; doi: https://doi.org/10.1101/280651 New Results

Immunology

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