Immunology

Monkeypox virus quadrivalent mRNA vaccine induces antibody responses and cellular immunity and protects mice against Vaccinia virus
Ye Sang, Zhen Zhang, Fan Liu, Haitao Lu, Changxiao Yu, Huisheng Sun, Jinrong Long, Yiming Cao, Jierui Mai, Xin Wang, Jiaxin Fang, Youchun Wang, Weijin Huang, Jing Yang, Shengqi Wang

bioRxiv 2022.11.22.517500; doi: https://doi.org/10.1101/2022.11.22.517500 New Results

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Haptoglobin buffers lipopolysaccharides to safeguard against aberrant NFκB activation
Laura Zein, Josina Grossmann, Helena Swoboda, Christina Borgel, Bernhard Wilke, Stephan Awe, Andrea Nist, Thorsten Stiewe, Oliver Stehling, Sven-Andreas Freibert, Till Adhikary, Ho-Ryun Chung

bioRxiv 2022.11.22.516855; doi: https://doi.org/10.1101/2022.11.22.516855 New Results

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In-depth characterization of the Syrian hamster as translational model for COVID-19 in humans
Martina Castellan, Gianpiero Zamperin, Giulia Franzoni, Greta Foiani, Maira Zorzan, Petra Drzewnioková, Marzia Mancin, Irene Brian, Alessio Bortolami, Matteo Pagliari, Annalisa Oggiano, Marta Vascellari, Valentina Panzarin, Sergio Crovella, Isabella Monne, Calogero Terregino, Paola De Benedictis, Stefania Leopardi

bioRxiv 2022.11.22.517339; doi: https://doi.org/10.1101/2022.11.22.517339 New Results

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Novel mRNA vaccines encoding Monkeypox virus M1R and A35R protect mice from a lethal virus challenge
Fujun Hou, Yuntao Zhang, Xiaohu Liu, Yanal Murad, Jiang Xu, Zhibin Yu, Xianwu Hua, Yingying Song, Jun Ding, Hongwei Huang, Ronghua Zhao, William Jia, Xiaoming Yang

bioRxiv 2022.11.19.517190; doi: https://doi.org/10.1101/2022.11.19.517190 New Results

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De novo identification of CD4+ T cell epitopes
Paul Zdinak, Stephanie Grebinoski, Jessica Torrey, Eduardo Zarate-Martinez, Louise Hicks, Rashi Ranjan, Nishtha Trivedi, Sanya Arshad, Mark Anderson, Dario AA Vignali, Alok V. Joglekar

bioRxiv 2022.11.21.517373; doi: https://doi.org/10.1101/2022.11.21.517373 New Results

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Anti-TNF-induced IL-27 modulates regulatory T cell responses in patients with IBD that respond to therapy
Raphael S. Peres, Tom Thomas, Matthias Friedrich, Mathilde Pohin, Claire Pearson, Ricardo C. Ferreira, Elizabeth H. Mann, Dominik Trzupek, Charlotte Rich-Griffin, Ashwin Jainarayanan, Kelsey Jones, Yisu Gu, John A. Todd, Oxford IBD Cohort Investigators, Holm H. Uhlig, Christopher D. Buckley, Calliope A. Dendrou, Simon Travis, Fiona M. Powrie

bioRxiv 2022.11.21.517257; doi: https://doi.org/10.1101/2022.11.21.517257 New Results

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Transcriptome network analysis implicates CX3CR1-positive type 3 dendritic cells in non-infectious uveitis
S. Hiddingh, A. Pandit, F.H. Verhagen, R. Rijken, N. H. Servaas, C.G.K. Wichers, N.H. ten Dam-van Loon, S.M. Imhof, T.R.D.J. Radstake, J.H. de Boer, J.J.W. Kuiper

bioRxiv 2021.11.16.468816; doi: https://doi.org/10.1101/2021.11.16.468816 New Results

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The use of non-functional clonotypes as a natural calibrator for quantitative bias correction in adaptive immune receptor repertoire profiling
Anastasia Smirnova, Anna Miroshnichenkova, Yulia Olshanskaya, Michael Maschan, Yuri Lebedev, Dmitriy Chudakov, Ilgar Mamedov, Alexander Komkov

bioRxiv 2021.03.24.436794; doi: https://doi.org/10.1101/2021.03.24.436794 New Results

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A multispecific antibody prevents immune escape and confers pan-SARS-CoV-2 neutralization
John Misasi, Ronnie R. Wei, Lingshu Wang, Amarendra Pegu, Chih-Jen Wei, Olamide K. Oloniniyi, Tongqing Zhou, Juan I. Moliva, Bingchun Zhao, Misook Choe, Eun Sung Yang, Yi Zhang, Marika Boruszczak, Man Chen, Kwan Leung, Juan Li, Zhi-Yong Yang, Hanne Andersen, Kevin Carlton, Sucheta Godbole, Darcy R. Harris, Amy R. Henry, Vera B. Ivleva, Paula Lei, Cuiping Liu, Lindsay Longobardi, Jonah S. Merriam, Danielle Nase, Adam S. Olia, Laurent Pessaint, Maciel Porto, Wei Shi, Jeremy J. Wolff, Daniel C. Douek, Mehul S. Suthar, Jason Gall, Richard A. Koup, Peter D. Kwong, John R. Mascola, Gary J. Nabel, Nancy J. Sullivan

bioRxiv 2022.07.29.502029; doi: https://doi.org/10.1101/2022.07.29.502029 New Results

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Characterizing adjuvants’ effects at the murine immunoglobulin repertoire level
Feng Feng, Rachel Yuen, Yumei Wang, Axin Hua, Thomas B. Kepler, Lee Wetzler

bioRxiv 2022.11.19.517218; doi: https://doi.org/10.1101/2022.11.19.517218 New Results

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Immunology

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