Immunology

Human IL-2 receptor β mutations associated with defects in immunity and peripheral tolerance
Zinan Zhang, Florian Gothe, Perrine Pennamen, John James, David MacDonald, Carlos P Mata, Yorgo Modis, Meghan Acres, Wolfram Haller, Claire Bowen, Rainer Doffinger, Jan Sinclair, Shannon Brothers, Anas Alazami, Yu Zhang, Helen Matthews, Sophie Naudion, Fanny Pelluard, Yasuhiro Yamazaki, Luigi Notarangelo, Hamoud Almousa, James Thaventhiran, Karin R Engelhardt, Sophie Hambleton, Caroline Rooryck, Ken G.C. Smith, Michael J Lenardo

bioRxiv 476697; doi: https://doi.org/10.1101/476697 New Results
TCR and inflammatory signals tune human MAIT cells to exert specific tissue repair and effector functions
Tianqi Leng, Thomas King, Matthias Friedrich, Zoe Christoforidou, Sarah McCuaig, Mastura Neyazi, Carolina V Arancibia-Carcamo, Fiona Powrie, Oxford IBD Investigators, Emanuele Marchi, Raphael Sanchesperes, Christian Willberg, Paul Klenerman

bioRxiv 475913; doi: https://doi.org/10.1101/475913 New Results
Quantitative analysis reveals reciprocal regulations underlying recovery dynamics of thymocytes and thymic environment
Kazumasa B Kaneko, Ryosuke Tateishi, Takahisa Miyao, Nobuko Akiyama, Ryo Yokota, Taishin Akiyama, Tetsuya J Kobayashi

bioRxiv 478164; doi: https://doi.org/10.1101/478164 New Results
Viral characteristics associated with sustenance of elite neutralizing activity in chronically HIV-1C infected monozygotic pediatric twins
Nitesh Mishra, Muzamil Ashraf Makhdoomi, Shaifali Sharma, Sanjeev Kumar, Deepshika Kumar, Himanshi Chawla, Ravinder Singh, Uma Kanga, Bimal Kumar Das, Rakesh Lodha, Sushil Kabra, Kalpana Luthra

bioRxiv 475822; doi: https://doi.org/10.1101/475822 New Results
Boosting subdominant neutralizing antibody responses with a computationally designed epitope-focused immunogen
Fabian Sesterhenn, Marie Galloux, Sabrina S Vollers, Lucia Csepregi, Che Yang, Delphyne Descamps, Jaume Bonet, Simon Friedensohn, Pablo Gainza, Patricia Corthesy, Man Chen, Stephane Rosset, Marie-Anne Rameix-Welti, Jean-François Eleouet, Sai T Reddy, Barney S Graham, Sabine Riffault, Bruno Correia

bioRxiv 430157; doi: https://doi.org/10.1101/430157 New Results
Facile method for screening clinical T cell receptors for off-target peptide-HLA reactivity
Marvin H Gee, Xinbo Yang, K. Christopher Garcia

bioRxiv 472480; doi: https://doi.org/10.1101/472480 New Results
Time-resolved systems analysis reveals a critical role of XCR1+ 1 dendritic cells in the maintenance of effector T cells during chronic viral infection
Jordi Argilaguet, Mireia Pedragosa, Anna Esteve-Codina, Graciela Riera, Enric Vidal, Cristina Peligero-Cruz, David Andreu, Tsuneyasu Kaisho, Gennady Bocharov, Burkhard Ludewig, Simon Heath, Andreas Meyerhans

bioRxiv 476077; doi: https://doi.org/10.1101/476077 New Results
CD8+ lymphocytes modulate acute ZIKV viremia, innate antiviral immunity and tissue dissemination in nonhuman primates
Blake Schouest, Marissa Fahlberg, Elizabeth A Scheef, Matthew J Ward, Kyra Headrick, Robert V Blair, Margaret H Gilbert, Lara A Doyle-Meyers, Victoria W Danner, Dawn M Wesson, Antonito T Panganiban, Nicholas J Maness

bioRxiv 475418; doi: https://doi.org/10.1101/475418 New Results
Meeting the challenges of high-dimensional data analysis in immunology
Christina Zielinski, Fabian Theis, Subarna Palit

bioRxiv 473215; doi: https://doi.org/10.1101/473215 New Results
Reporters of TCR signaling identify arthritogenic T cells in murine and human autoimmune arthritis
Judith Ashouri, Lih-Yun Hsu, Yiling Chen, Steven Yu, Debra Chang, Eric Hansen, Lisa Lattanza, Julie Zikherman, Arthur Weiss

bioRxiv 474700; doi: https://doi.org/10.1101/474700 New Results

Immunology

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