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Immunology

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  • Human IFNε: Spaciotemporal expression, hormone regulation and innate immunity in the female reproductive tract
    Nollaig M. Bourke, Sharon L. Achilles, Stephanie U. Huang, Helen E. Cumming, Irene Papageorgio, Linden J. Gearing, Suruchi Thakore, Niamh E. Mangan, Sam Mesiano, Paul J. Hertzog
    bioRxiv 445007; doi: https://doi.org/10.1101/445007
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  • PD-1 suppresses the maintenance of cell couples between cytotoxic T cells and tumor target cells within the tumor
    Rachel Ambler, Grace L. Edmunds, Giulia Toti, David J. Morgan, Christoph Wülfing
    bioRxiv 443788; doi: https://doi.org/10.1101/443788
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  • Crystal structure of m4-1BB/4-1BBL complex reveals an unusual dimeric ligand that undergoes structural changes upon receptor binding
    Aruna Bitra, Tzanko Doukov, Giuseppe Destito, Michael Croft, Dirk M. Zajonc
    bioRxiv 444554; doi: https://doi.org/10.1101/444554
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  • Programmed Delayed Splicing: A Mechanism for Timed Inflammatory Gene Expression
    Devdoot S. Majumdar, Luke Frankiw, Christian H. Burns, Yvette Garcia-Flores, David Baltimore
    bioRxiv 443796; doi: https://doi.org/10.1101/443796
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  • Interfacial actin protrusions mechanically potentiate killing by cytotoxic T cells
    Fella Tamzalit, Mitchell S. Wang, Weiyang Jin, Vitaly Boyko, John M. Heddleston, Charles T. Black, Lance C. Kam, Morgan Huse
    bioRxiv 443309; doi: https://doi.org/10.1101/443309
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  • Stochastic simulations show how passive immunization can influence the germinal centre reaction and optimize host humoral responses
    Amar K. Garg, Rajat Desikan, Narendra M. Dixit
    bioRxiv 441691; doi: https://doi.org/10.1101/441691
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  • Mast Cells Enhance Sterile Inflammation in Chronic Nonbacterial Osteomyelitis
    Stephanie Young, Namit Sharma, Jae Hoon Peter Lee, Violeta Chitu, Volker Neumeister, Elisabeth Sohr, E. Richard Stanley, Christian M. Hedrich, Andrew W.B. Craig
    bioRxiv 259275; doi: https://doi.org/10.1101/259275
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  • TCR-pMHC bond length controls TCR ligand discrimination
    Dibyendu K. Sasmal, Wei Feng, Sobhan Roy, Peter Leung, Yanran He, Chufan Cai, Guoshuai Cao, Huada Lian, Jian Qin, Enfu Hui, Hans Schreiber, Erin Adams, Jun Huang
    bioRxiv 433938; doi: https://doi.org/10.1101/433938
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  • Haematological parameters and plasma levels of 8-iso-prostaglandin F2α in malaria-sickle cell co-morbidity: A cross sectional study
    Enoch Aninagyei, Emmanuel Doku Tetteh, Josephine Banini, Emmanuel Nani, Patrick Adu, Richard K. D. Ephraim, Alexander Egyir-Yawson, Desmond Omane Acheampong
    bioRxiv 441998; doi: https://doi.org/10.1101/441998
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  • Antigen receptor locus dynamics is orchestrated near the sol-gel phase transition to enforce stepwise VDJ gene rearrangement
    Nimish Khanna, Yaojun Zhang, Joseph S. Lucas, Olga K. Dudko, Cornelis Murre
    bioRxiv 441444; doi: https://doi.org/10.1101/441444
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