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Immunology

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  • Light-based tuning of ligand half-life supports kinetic proofreading model of T cell activation
    Doug Tischer, Orion D. Weiner
    bioRxiv 432864; doi: https://doi.org/10.1101/432864
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  • Intestinal Serum Amyloid A suppresses systemic neutrophil activation and bactericidal activity in response to microbiota colonization
    Caitlin C. Murdoch, Scott T. Espenschied, Molly A. Matty, Olaf Mueller, David M. Tobin, John F. Rawls
    bioRxiv 435503; doi: https://doi.org/10.1101/435503
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  • Endogenous retroviruses transcriptional modulation after severe infection, trauma and burn
    Olivier Tabone, Marine Mommert, Camille Jourdan, Elisabeth Cerrato, Matthieu Legrand, Alain Lepape, Bernard Allaouchiche, Thomas Rimmelé, Alexandre Pachot, Guillaume Monneret, Fabienne Venet, François Mallet, Julien Textoris
    bioRxiv 433029; doi: https://doi.org/10.1101/433029
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  • Innate Immune Priming by cGAS as a Preparatory Countermeasure Against RNA Virus Infection
    Michael T. Parker, Smita Gopinath, Corey E. Perez, Melissa M. Linehan, Jason M. Crawford, Akiko Iwasaki, Brett D. Lindenbach
    bioRxiv 434027; doi: https://doi.org/10.1101/434027
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  • Expression of a recombinant high affinity IgG Fc receptor by engineered NK cells as a docking platform for therapeutic mAbs to target cancer cells
    Kristin M. Snyder, Robert Hullsiek, Hemant K Mishra, Daniel C. Mendez, Yunfang Li, Allison Rogich, Dan S. Kaufman, Jianming Wu, Bruce Walcheck
    bioRxiv 432849; doi: https://doi.org/10.1101/432849
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  • Slow delivery immunization enhances HIV neutralizing antibody and germinal center responses via modulation of immunodominance
    Kimberly M. Cirelli, Diane G. Carnathan, Bartek Nogal, Oscar L. Rodriguez, Jacob T. Martin, Amit A. Upadhyay, Chiamaka A. Enemuo, Etse H. Gebru, Yury Choe, Federico Viviano, Catherine Nakao, Matthias Pauthner, Samantha Reiss, Christopher A. Cottrell, Raiza Bastidas, William Gibson, Amber N. Wolabaugh, Mariane B. Melo, Benjamin Cosette, Venkatesh Kuman, Nirav Patel, Talar Tokatlian, Sergey Menis, Daniel W. Kulp, Dennis R. Burton, Ben Murrell, Steven E. Bosinger, William R. Schief, Andrew B. Ward, Corey T. Watson, Guido Silvestri, Darrell J. Irvine, Shane Crotty
    bioRxiv 432666; doi: https://doi.org/10.1101/432666
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  • Immune regeneration in irradiated mice is not impaired by the absence of DPP9 enzymatic activity
    Margaret G. Gall, Hui Emma Zhang, Adam Cook, Christopher J. Jolly, Geoffrey W. McCaughan, Ben Roediger, Mark D. Gorrell
    bioRxiv 431775; doi: https://doi.org/10.1101/431775
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  • Optogenetic control shows that kinetic proofreading regulates the activity of the T cell receptor
    O. Sascha Yousefi, Matthias Günther, Maximilian Hörner, Julia Chalupsky, Maximilian Wess, Simon M. Brandl, Robert W. Smith, Christian Fleck, Tim Kunkel, Matias D. Zurbriggen, Thomas Höfer, Wilfried Weber, Wolfgang W.A. Schamel
    bioRxiv 432740; doi: https://doi.org/10.1101/432740
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  • A Genetically Engineered Primary Human Natural Killer Cell Platform for Cancer Immunotherapy
    Emily J. Pomeroy, John T. Hunzeker, Mitchell T. Kluesner, Margaret R. Crosby, Walker S. Lahr, Laura Bendzick, Jeffrey S. Miller, Beau R. Webber, Melissa A. Geller, Bruce Walcheck, Martin Felices, Timothy K. Starr, Branden S. Moriarity
    bioRxiv 430553; doi: https://doi.org/10.1101/430553
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  • High diversity, turnover, and structural constraints characterize TCR α and β repertoire selection
    Larisa Kamga, Anna Gil, Inyoung Song, Ramakanth Chirravuri, Nuray Aslan, Dario Ghersi, Lawrence J. Stern, Liisa K. Selin, Katherine Luzuriaga
    bioRxiv 428623; doi: https://doi.org/10.1101/428623
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