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Immunology

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  • Molecular Landscape of Anti-Drug Antibodies Reveals the Mechanism of the Immune Response Following Treatment with TNFα Antagonists
    Anna Vaisman-Mentesh, Shai Rosenstein, Miri Yavzori, Yael Dror, Ella Fudim, Bella Ungar, Uri Kopylov, Orit Picard, Aya Kigel, Shomron Ben-Horin, Itai Benhar, Yariv Wine
    bioRxiv 509489; doi: https://doi.org/10.1101/509489
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  • Dissecting molecular regulatory mechanisms underlying noncoding susceptibility SNPs associated with 19 autoimmune diseases using multi-omics integrative analysis
    Xiao-Feng Chen, Min-Rui Guo, Yuan-Yuan Duan, Feng Jiang, Hao Wu, Shan-Shan Dong, Hlaing Nwe Thynn, Cong-Cong Liu, Lin Zhang, Yan Guo, Tie-Lin Yang
    bioRxiv 871384; doi: https://doi.org/10.1101/871384
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  • Ulcerative colitis is characterized by amplified acute inflammation with delayed resolution
    Riccardo Wysoczanski, Alexandra C Kendall, Madhur Motwani, Roser Vega, Farooq Z Rahman, Sara McCartney, Stuart L Bloom, Anna Nicolaou, Derek W Gilroy, Anthony W Segal, Daniel J B Marks
    bioRxiv 870139; doi: https://doi.org/10.1101/870139
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  • Choroid-resident macrophages maintain local vasculature and RPE integrity and spontaneously regenerate following depletion
    Xiao Yang, Lian Zhao, Maria M. Campos, Mones Abu-Asab, Davide Ortolan, Nathan Hotaling, Kapil Bharti, Wai T. Wong
    bioRxiv 868430; doi: https://doi.org/10.1101/868430
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  • Housing laboratory mice deficient for Nod2 and Atg16l1 in a natural environment uncovers genetic and environmental contributions to immune variation
    Jian-Da Lin, Joseph C. Devlin, Frank Yeung, Caroline McCauley, Jacqueline M. Leung, Ying-Han Chen, Alex Cronkite, Christina Hansen, Charlotte Drake-Dunn, Kelly V. Ruggles, Ken Cadwell, Andrea L. Graham, P’ng Loke
    bioRxiv 741470; doi: https://doi.org/10.1101/741470
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  • Altered immunity of laboratory mice in the natural environment is associated with fungal colonization
    Frank Yeung, Ying-Han Chen, Jian-Da Lin, Jacqueline M. Leung, Caroline McCauley, Joseph C. Devlin, Christina Hansen, Alex Cronkite, Zac Stephens, Charlotte Drake-Dunn, Yi Fulmer, Bo Shopsin, Kelly V. Ruggles, June L. Round, P’ng Loke, Andrea L. Graham, Ken Cadwell
    bioRxiv 742387; doi: https://doi.org/10.1101/742387
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  • Sex-based mutational landscape confers sensitivity to checkpoint blockade immunotherapy in cutaneous melanoma
    Mingming Jia, Tian Chi
    bioRxiv 868950; doi: https://doi.org/10.1101/868950
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  • Extracellular adenosine enhances the ability of PMNs to kill Streptococcus pneumoniae by inhibiting IL-10 production
    Nalat Siwapornchai, James N. Lee, Essi Y. I. Tchalla, Manmeet Bhalla, Jun Hui Yeoh, Sara E. Roggensack, John M. Leong, Elsa N. Bou Ghanem
    bioRxiv 716456; doi: https://doi.org/10.1101/716456
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  • VIP-producing enteric neurons interact with innate lymphoid cells to regulate feeding-dependent intestinal epithelial barrier functions
    Jhimmy Talbot, Paul Hahn, Lina Kroehling, Henry Nguyen, Dayi Li, Dan R. Littman
    bioRxiv 721464; doi: https://doi.org/10.1101/721464
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  • The Phlebotomus papatasi transcriptomic response to trypanosomatid-contaminated blood is robust but non-specific
    Megan A. Sloan, Jovana Sadlova, Tereza Lestinova, Mandy J. Sanders, James A. Cotton, Petr Volf, Petros Ligoxygakis
    bioRxiv 867382; doi: https://doi.org/10.1101/867382
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