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Immunology

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  • Aging induces Nlrp3 inflammasome dependent adipose B cell expansion to impair metabolic homeostasis
    Christina D. Camell, Aileen Lee, Patrick Günther, Emily L. Goldberg, Olga Spadaro, Yun-Hee Youm, Andrzej Bartke, Gene B. Hubbard, Yuji Ikeno, Nancy H. Ruddle, Joachim Schultze, Vishwa Deep Dixit
    bioRxiv 607192; doi: https://doi.org/10.1101/607192
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  • Extensive CD8β depletion does not prevent control of viral replication or protection from challenge in macaques chronically infected with a live attenuated simian immunodeficiency virus
    Matthew S. Sutton, Amy Ellis-Connell, Alexis J. Balgeman, Gabrielle Barry, Andrea M. Weiler, Scott J. Hetzel, Yan Zhou, Annie Kilby, Rosemarie D. Mason, Kristin K. Biris, John R. Mascola, Nancy J. Sullivan, Mario Roederer, Thomas C. Friedrich, Shelby L. O’Connor
    bioRxiv 608554; doi: https://doi.org/10.1101/608554
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  • Indomethacin-induced gut damage in a surrogate insect model, Galleria mellonella
    Helena Emery, Richard Johnston, Andrew F. Rowley, Christopher J. Coates
    bioRxiv 606319; doi: https://doi.org/10.1101/606319
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  • Rapid discovery of synthetic DNA sequences to rewrite endogenous T cell circuits
    Theodore L. Roth, P. Jonathan Li, Jasper F. Nies, Ruby Yu, Michelle L.T. Nguyen, Youjin Lee, Ryan Apathy, Anna Truong, Joseph Hiatt, David Wu, David N. Nguyen, Daniel Goodman, Jeffrey A. Bluestone, Kole Roybal, Eric Shifrut, Alexander Marson
    bioRxiv 604561; doi: https://doi.org/10.1101/604561
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  • Interleukin-17 and senescence regulate the foreign body response
    Liam Chung, David Maestas Jr, Andriana Lebid, Ashlie Mageau, Gedge D. Rosson, Xinqun Wu, Matthew T Wolf, Ada Tam, Isabel Vanderzee, Xiaokun Wang, James I Andorko, Radhika Narain, Kaitlyn Sadtler, Hongni Fan, Daniela Čiháková, Claude Jourdan Le Saux, Franck Housseau, Drew M Pardoll, Jennifer H. Elisseeff
    bioRxiv 583757; doi: https://doi.org/10.1101/583757
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  • Imaging toxin-induced neuroinflammation in mice using hyperpolarized 13C magnetic resonance spectroscopy
    Lydia M Le Page, Caroline Guglielmetti, Chloé Najac, Brice Tiret, Myriam M Chaumeil
    bioRxiv 605568; doi: https://doi.org/10.1101/605568
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  • Differential nanoscale organisation of LFA-1 modulates T cell migration
    Michael J. Shannon, Judith Pineau, Juliette Griffié, Jesse Aaron, Tamlyn Peel, David J. Williamson, Rose Zamoyska, Andrew P. Cope, Georgina H. Cornish, Dylan M. Owen
    bioRxiv 602326; doi: https://doi.org/10.1101/602326
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  • Neuropilin-1 regulates the secondary CD8 T cell response to virus infection
    Ji Young Hwang, Yanbo Sun, Christopher R. Carroll, Edward J Usherwood
    bioRxiv 605816; doi: https://doi.org/10.1101/605816
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  • Innate CD8αα+ cells and osteopontin promote ILC1-like intraepithelial lymphocyte homeostasis and intestinal inflammation
    Ali Nazmi, Kristen Hoek, Michael J. Greer, M. Blanca Piazuelo, Nagahiro Minato, Danyvid Olivares-Villagómez
    bioRxiv 606616; doi: https://doi.org/10.1101/606616
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  • Development of a KDM6b shRNA conditional knock down mouse model
    Julia E. Prier, Marnie E. Blewitt, Ross A. Dickins, Stephen J. Turner
    bioRxiv 605618; doi: https://doi.org/10.1101/605618
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