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Immunology

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  • B cell defects observed in Nod2 knockout mice are a consequence of a Dock2 mutation frequently found in inbred strains
    Serre-Yu Wong, Maryaline Coffre, Deepshika Ramanan, Luis E. Gomez, Lauren Peters, Eric Schadt, Sergei Koralov, Ken Cadwell
    bioRxiv 242586; doi: https://doi.org/10.1101/242586
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  • Representativeness and robustness of TCR repertoire diversity assessment by high-throughput sequencing
    Wahiba Chaara, Encarnita Mariotti-Ferrandiz, Ariadna Gonzalez-Tort, Laura Florez, Adrien Six, David Klatzmann
    bioRxiv 242024; doi: https://doi.org/10.1101/242024
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  • Caffeine downregulates inflammatory pathways involved in autoimmunity
    Merve Iris, Pei-Suen Tsou, Amr H. Sawalha
    bioRxiv 241539; doi: https://doi.org/10.1101/241539
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  • Pharmacological Macrophage Attenuation by Imatinib Reverts Hepatic Steatosis and Inflammation in Obese Mice
    Shefaa AlAsfoor, Theresa V. Rohm, Angela J. T. Bosch, Thomas Dervos, Diego Calabrese, Matthias S. Matter, Achim Weber, Claudia Cavelti-Weder
    bioRxiv 241224; doi: https://doi.org/10.1101/241224
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  • Genome-wide CRISPR screens in T helper cells reveal pervasive cross-talk between activation and differentiation
    Johan Henriksson, Xi Chen, Tomás Gomes, Ubaid Ullah, Kerstin B Meyer, Ricardo Miragaia, Graham Duddy, Jhuma Pramanik, Kosuke Yusa, Riitta Lahesmaa, Sarah A Teichmann
    bioRxiv 196022; doi: https://doi.org/10.1101/196022
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  • B1a B cells require autophagy for metabolic homeostasis and self-renewal
    Alexander J Clarke, Thomas Riffelmacher, Daniel Braas, Richard J Cornall, Anna Katharina Simon
    bioRxiv 240523; doi: https://doi.org/10.1101/240523
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  • Comprehensive profiling of TCRβ repertoire in a non-model species (the bank vole) using high-throughput sequencing
    Magdalena Migalska, Alvaro Sebastian, Jacek Radwan
    bioRxiv 217653; doi: https://doi.org/10.1101/217653
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  • Evolutionary Origin of the Mammalian Hematopoietic System Found in a Colonial Chordate
    Benyamin Rosental, Mark Kowarsky, Jun Seita, Daniel M. Corey, Katherine J. Ishizuka, Karla J. Palmeri, Shih-Yu Chen, Rahul Sinha, Jennifer Okamoto, Gary Mantalas, Lucia Manni, Tal Raveh, D. Nathaniel Clarke, Aaron M. Newman, Norma F. Neff, Garry P. Nolan, Stephen R. Quake, Irving L. Weissman, Ayelet Voskoboynik
    bioRxiv 206318; doi: https://doi.org/10.1101/206318
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  • Unbiased classification of mosquito blood cells by single-cell genomics and high-content imaging
    Maiara S. Severo, Jonathan J.M. Landry, Randall L. Lindquist, Christian Goosmann, Volker Brinkmann, Paul Collier, Anja E. Hauser, Vladimir Benes, Johan Henriksson, Sarah A. Teichmann, Elena A. Levashina
    bioRxiv 234492; doi: https://doi.org/10.1101/234492
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  • The Phagocyte Oxidase Controls Tolerance to Mycobacterium tuberculosis infection
    Andrew J Olive, Clare M Smith, Michael C Kiritsy, Christopher M Sassetti
    bioRxiv 232777; doi: https://doi.org/10.1101/232777
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