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Immunology

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  • Interferon-α promotes neo-antigen formation and preferential HLA-B-restricted antigen presentation in pancreatic β-cells
    Alexia Carré, Zhicheng Zhou, Javier Perez-Hernandez, Fatoumata Samassa, Christiana Lekka, Anthony Manganaro, Masaya Oshima, Hanqing Liao, Robert Parker, Annalisa Nicastri, Barbara Brandao, Maikel L. Colli, Decio L. Eizirik, Marcus Göransson, Orlando Burgos Morales, Amanda Anderson, Laurie Landry, Farah Kobaisi, Raphael Scharfmann, Lorella Marselli, Piero Marchetti, Sylvaine You, Maki Nakayama, Sine R. Hadrup, Sally C. Kent, Sarah J. Richardson, Nicola Ternette, Roberto Mallone
    bioRxiv 2023.09.15.557918; doi: https://doi.org/10.1101/2023.09.15.557918 New Results
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  • Exponentially decreasing exposure of antigen generates anti-inflammatory T-cell responses
    Arezoo Esrafili, Joshua Kupfer, Abhirami Thumsi, Madhan Mohan Chandra Sekhar Jaggarapu, Abhirami P. Suresh, Aleksandr Talitckii, Taravat Khodaei, Srivatsan J. Swaminathan, Shivani Mantri, Matthew M Peet, Abhinav P. Acharya
    bioRxiv 2023.09.15.558014; doi: https://doi.org/10.1101/2023.09.15.558014 New Results
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  • PD-1 Mediated Regulation of Unique Activated CD8+ T Cells by NK Cells in the Submandibular Gland
    Samantha M. Borys, Shanelle P. Reilly, Ian Magill, David Zemmour, Laurent Brossay
    bioRxiv 2023.09.15.557930; doi: https://doi.org/10.1101/2023.09.15.557930 New Results
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  • Proteomic adaptations in the kidney reveal orchestration of local and secreted antimicrobial peptides in human pyelonephritis
    Lars Borgards, Bente Siebels, Hannah Voss, Christoph Krisp, Jessica Schmitz, Lisa Schwarz, Devon Siemes, Philippa Spangenberg, Jan H Bräsen, Sibylle von Vietinghoff, Hartmut Schlüter, Florian Wagenlehner, Daniel R. Engel, Olga Shevchuk
    bioRxiv 2023.09.14.557715; doi: https://doi.org/10.1101/2023.09.14.557715 New Results
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  • Keras/TensorFlow in Drug Design for Immunity Disorders
    Paulina Dragan, Kavita Joshi, Alessandro Atzei, Dorota Latek
    bioRxiv 2023.09.14.557712; doi: https://doi.org/10.1101/2023.09.14.557712 New Results
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  • Elastin-derived peptides favor type 2 innate lymphoid cells in COPD
    Sarah Lahire, Caroline Fichel, Océane Rubaszewski, Cédric Lerévérend, Sandra Audonnet, Vincent Visneux, Jeanne-Marie Perotin, Gaëtan Deslée, Sébastien Le Jan, Stéphane Potteaux, Richard Le Naour, Arnaud Pommier
    bioRxiv 2023.09.13.557567; doi: https://doi.org/10.1101/2023.09.13.557567 New Results
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  • Engineered Immunogens to Elicit Antibodies Against Conserved Coronavirus Epitopes
    Brenda Kapingidza, Daniel J. Marston, Caitlin Harris, Daniel Wrapp, Kaitlyn Winters, Dieter Mielke, Lu Xiaozhi, Qi Yin, Andrew Foulger, Rob Parks, Maggie Barr, Amanda Newman, Alexandra Schäfer, Amanda Eaton, Justine Mae Flores, Austin Harner, Nicholas J Cantazaro Jr., Michael L Mallory, Melissa D Mattocks, Christopher Beverly, Brianna Rhodes, Katayoun Mansouri, Elizabeth Van Itallie, Pranay Vure, Brooke Manness, Taylor Keyes, Sherry Stanfield-Oakley, Christopher W. Woods, Elizabeth A. Petzold, Emmanuel B Walter, Kevin Wiehe, Robert J. Edwards, David Montefiori, Guido Ferrari, Ralph Baric, Derek W. Cain, Kevin O. Saunders, Barton F. Haynes, Mihai L. Azoitei
    bioRxiv 2023.02.27.530277; doi: https://doi.org/10.1101/2023.02.27.530277 New Results
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  • CD39 expression by regulatory T cells drives CD8+ T cell suppression during experimental Trypanosoma cruzi infection
    Cintia L. Araujo Furlan, Santiago Boccardo, Constanza Rodriguez, Simon C. Robson, Adriana Gruppi, Carolina L. Montes, Eva V. Acosta Rodríguez
    bioRxiv 2023.09.14.557792; doi: https://doi.org/10.1101/2023.09.14.557792 New Results
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  • γδ T cells impair airway macrophage differentiation in lung adenocarcinoma
    Ximena L. Raffo-Iraolagoitia, Amanda J. McFarlane, Bjorn Kruspig, Frédéric Fercoq, Judith Secklehner, Marco De Donatis, John B. G. Mackey, Robert Wiesheu, Sarah Laing, Ya-Ching Hsieh, Robin Shaw, Ryan Corbyn, Colin Nixon, Crispin Miller, Kristina Kirschner, Calum C. Bain, Daniel J. Murphy, Seth B. Coffelt, Leo M. Carlin
    bioRxiv 2023.09.14.557344; doi: https://doi.org/10.1101/2023.09.14.557344 New Results
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  • Blimp-1 and c-Maf regulate common and unique gene networks to protect against distinct pathways of pathobiont-induced colitis
    Marisol Alvarez-Martinez, Luke S. Cox, Claire F. Pearson, William J. Branchett, Probir Chakravarty, Xuemei Wu, Hubert Slawinski, Alaa Al-Dibouni, Vasileios A. Samelis, Leona Gabryšová, Simon L. Priestnall, Alejandro Suárez-Bonnet, Anna Mikolajczak, James Briscoe, Fiona Powrie, Anne O’Garra
    bioRxiv 2023.09.14.557705; doi: https://doi.org/10.1101/2023.09.14.557705 New Results
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