Immunology

CD4+ T-cell epitope prediction by combined analysis of antigen conformational flexibility and peptide-MHCII binding affinity
Tysheena Charles, Daniel L. Moss, Pawan Bhat, Peyton W. Moore, Nicholas A. Kummer, Avik Bhattacharya, Ramgopal R. Mettu, Samuel J. Landry

bioRxiv 2020.05.21.109967; doi: https://doi.org/10.1101/2020.05.21.109967 New Results

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CD45 pre-exclusion from the tips of microvilli establishes a phosphatase-free zone for early TCR triggering
Yunmin Jung, Lai Wen, Amnon Altman, Klaus Ley

bioRxiv 2020.05.21.109074; doi: https://doi.org/10.1101/2020.05.21.109074 New Results

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Yeast-Expressed SARS-CoV Recombinant Receptor-Binding Domain (RBD219-N1) Formulated with Alum Induces Protective Immunity and Reduces Immune Enhancement
Wen-Hsiang Chen, Xinrong Tao, Anurodh Agrawal, Abdullah Algaissi, Bi-Hung Peng, Jeroen Pollet, Ulrich Strych, Maria Elena Bottazzi, Peter J. Hotez, Sara Lustigman, Lanying Du, Shibo Jiang, Chien-Te K. Tseng

bioRxiv 2020.05.15.098079; doi: https://doi.org/10.1101/2020.05.15.098079 New Results

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Netome: The Molecular Characterization of Neutrophil Extracellular Traps (NETs)
David Scieszka, Yi-Han Lin, Weizhong Li, Saibyasachi Choudhury, Yanbao Yu, Marcelo Freire

bioRxiv 2020.05.18.102772; doi: https://doi.org/10.1101/2020.05.18.102772 New Results

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Convergent Antibody Responses to SARS-CoV-2 Infection in Convalescent Individuals
Davide F. Robbiani, Christian Gaebler, Frauke Muecksch, Julio C. C. Lorenzi, Zijun Wang, Alice Cho, Marianna Agudelo, Christopher O. Barnes, Anna Gazumyan, Shlomo Finkin, Thomas Hagglof, Thiago Y. Oliveira, Charlotte Viant, Arlene Hurley, Hans-Heinrich Hoffmann, Katrina G. Millard, Rhonda G. Kost, Melissa Cipolla, Kristie Gordon, Filippo Bianchini, Spencer T. Chen, Victor Ramos, Roshni Patel, Juan Dizon, Irina Shimeliovich, Pilar Mendoza, Harald Hartweger, Lilian Nogueira, Maggi Pack, Jill Horowitz, Fabian Schmidt, Yiska Weisblum, Eleftherios Michailidis, Alison W. Ashbrook, Eric Waltari, John E. Pak, Kathryn E. Huey-Tubman, Nicholas Koranda, Pauline R. Hoffman, Anthony P. West Jr., Charles M. Rice, Theodora Hatziioannou, Pamela J. Bjorkman, Paul D. Bieniasz, Marina Caskey, Michel C. Nussenzweig

bioRxiv 2020.05.13.092619; doi: https://doi.org/10.1101/2020.05.13.092619 New Results

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An insertion unique to SARS-CoV-2 exhibits superantigenic character strengthened by recent mutations
Mary Hongying Cheng, She Zhang, Rebecca A. Porritt, Moshe Arditi, Ivet Bahar

bioRxiv 2020.05.21.109272; doi: https://doi.org/10.1101/2020.05.21.109272 New Results

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IgY antibodies against Ebola virus possess post-exposure protection and excellent thermostability
Yuan Zhang, Yanqiu Wei, Yunlong Li, Xuan Wang, Yang Liu, Deyu Tian, Xiaojuan Jia, Rui Gong, Wenjun Liu, Limin Yang

bioRxiv 2020.05.21.108159; doi: https://doi.org/10.1101/2020.05.21.108159 New Results

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Development of follicular dendritic cells in lymph nodes depends on retinoic acid mediated signaling
Jasper J. Koning, Anusha Rajaraman, Rogier M. Reijmers, Tanja Konijn, Junliang Pan, Carl F. Ware, Eugene C. Butcher, Reina E. Mebius

bioRxiv 2020.05.20.106385; doi: https://doi.org/10.1101/2020.05.20.106385 New Results

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Schistosoma mansoni infection reprograms the metabolic potential of the myeloid lineage in a mouse model of metabolic syndrome
Diana Cortes-Selva, Lisa Gibbs, J. Alan Maschek, Tyler Van Ry, Bartek Rajwa, James E. Cox, Eyal Amiel, Keke C. Fairfax

bioRxiv 2020.04.20.050898; doi: https://doi.org/10.1101/2020.04.20.050898 New Results

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A defect in COPI-mediated transport of STING causes immune dysregulation in COPA syndrome
Zimu Deng, Zhenlu Chong, Christopher S. Law, Kojiro Mukai, Frances O. Ho, Tereza Martinu, Bradley J. Backes, Walter L. Eckalbar, Tomohiko Taguchi, Anthony K. Shum

bioRxiv 2020.05.20.106500; doi: https://doi.org/10.1101/2020.05.20.106500 New Results

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Immunology

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