Immunology

Inflammatory bowel disease microbiotas alter gut CD4 T-cell homeostasis and drive colitis in mice
Graham J Britton, Eduardo J Contijoch, Ilaria Mogno, Olivia H Vennaro, Sean R Llewellyn, Ruby Ng, Zhihua Li, Arthur Mortha, Miriam Merad, Anuk Das, Dirk Gevers, Dermot PB McGovern, Namita Singh, Jonathan Braun, Jonathan P Jacobs, Jose C Clemente, Ari Grinspan, Bruce E Sands, Jean-Frederic Colombel, Marla C Dubinsky, Jeremiah J Faith

bioRxiv 276774; doi: https://doi.org/10.1101/276774 New Results
A protocol for single-cell transcriptomics from cryopreserved renal tissue and urine for the Accelerating Medicine Partnership (AMP) RA/SLE network
Deepak A. Rao, Celine C Berthier, Arnon Arazi, Anne Davidson, Yanyan Liu, Edward P. Browne, Thomas M. Eisenhaure, Adam Chicoine, David J. Lieb, Dawn E. Smilek, Patti Tosta, James A. Lederer, Michael B. Brenner, David Hildeman, E. Steve Woodle, David Wofsy, Jennifer H. Anolik, Matthias Kretzler, Accelerating Medicines Partnership RA/SLE Network, Nir Hacohen, Betty Diamond

bioRxiv 275859; doi: https://doi.org/10.1101/275859 New Results
Perturbation of ubiquitin homeostasis promotes macrophage oxidative defenses
Marie-Eve Charbonneau, Karla Passalacqua, Susan Hagen, Hollis Showalter, Christiane Wobus, Mary O'Riordan

bioRxiv 276964; doi: https://doi.org/10.1101/276964 New Results
Mitochondria-derived vesicles deliver antimicrobial payload to control phagosomal bacteria
Basel Abuaita, Tracey Schultz, Mary O'Riordan

bioRxiv 277004; doi: https://doi.org/10.1101/277004 New Results
The fungal ligand chitin directly binds and signals inflammation dependent on oligomer size and TLR2
Katharina Fuchs, Yamel Cardona Gloria, Olaf-Oliver Wolz, Franziska Herster, Lokesh Sharma, Carly Dillen, Christoph Täumer, Sabine Dickhöfer, Zsofia Bittner, Truong-Minh Dang, Anuragh Singh, Daniel Haischer, Maria A Schlöffel, Kirsten J Koymans, Tharmila Sanmuganantham, Milena Krach, Nadine A Schilling, Felix Frauhammer, Lloyd Miller, Thorsten Nürnberger, Salomé LeibundGut-Landmann, Andrea A Gust, Boris Macek, Martin Frank, Cécile Gouttefangeas, Charles S Dela-Cruz, Dominik Hartl, Alexander Weber

bioRxiv 270405; doi: https://doi.org/10.1101/270405 New Results
A mouse model of maternal obesity leads to uterine natural killer (uNK) cell activation and uterine artery remodeling defects
Jennet Baltayeva, Barbara Castellana, Danielle Mara, Julian K Christians, Alexander G Beristain

bioRxiv 275503; doi: https://doi.org/10.1101/275503 New Results
Predicting the spectrum of TCR repertoire sharing with a data-driven model of recombination
Yuval Elhanati, Zachary Sethna, Curtis G Callan Jr., Thierry Mora, Aleksandra M Walczak

bioRxiv 275602; doi: https://doi.org/10.1101/275602 New Results
Anti-HIV-1 B cell responses are dependent on B cell precursor frequency and antigen binding affinity
Pia Dosenovic, Ervin E Kara, Anna-Klara Pettersson, Andrew McGuire, Matthew Gray, Harald Hartweger, Eddy S Thientosapol, Leonidas Stamatatos, Michel C Nussenzweig

bioRxiv 275438; doi: https://doi.org/10.1101/275438 New Results
Perforin-2 Permeabilizes the Envelope of Phagocytosed Bacteria
Fangfang Bai, Ryan McCormack, Suzanne Hower, Gregory V Plano, Mathias Lichtenheld, George P Munson

bioRxiv 274878; doi: https://doi.org/10.1101/274878 New Results
RNASeq analysis identifies non-canonical role of STAT2 and IRF9 in the regulation of a STAT1-independent antiviral and immunoregulatory transcriptional program induced by IFNβ and TNFα
Mélissa Mariani, Pouria Dasmeh, Audray Fortin, Mario Kalamujic, Elise Caron, Alexander N Harrison, Sandra Cervantes-Ortiz, Espérance Mukawera, Adrian Serohijos, Nathalie Grandvaux

bioRxiv 273623; doi: https://doi.org/10.1101/273623 New Results

Immunology

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