Immunology

The plasma biomarker soluble SIGLEC-1 is associated with the type I interferon transcriptional signature, ethnic background and renal disease in systemic lupus erythematosus
João J. Oliveira, Sarah Karrar, Daniel B. Rainbow, Christopher L. Pinder, Pamela Clarke, Arcadio Rubio García, Osama Al-Assar, Keith Burling, Tim J. Vyse, Linda S. Wicker, John A. Todd, Ricardo C. Ferreira

bioRxiv 266965; doi: https://doi.org/10.1101/266965

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Primate MHC class I from Genomes
D.N. Olivieri, F. Gambón-Deza

bioRxiv 266064; doi: https://doi.org/10.1101/266064

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A long-chain fatty acid elongase Elovl6 regulates mechanical damage–induced keratinocyte death and skin inflammation
Yoshiyuki Nakamura, Takashi Matsuzaka, Satoko Tahara-Hanaoka, Kazuko Shibuya, Hitoshi Shimano, Chigusa Nakahashi-Oda, Akira Shibuya

bioRxiv 264838; doi: https://doi.org/10.1101/264838

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HLA-B*39:06 Efficiently Mediates Type 1 Diabetes in a Mouse Model Incorporating Reduced Thymic Insulin Expression¹
Jennifer Schloss, Riyasat Ali, Jeremy J. Racine, Harold D. Chapman, David V. Serreze, Teresa P. DiLorenzo

bioRxiv 264531; doi: https://doi.org/10.1101/264531

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TCR-MHC Interaction Strength Defines Trafficking and Resident Memory Status of CD8 T cells in the Brain
Anna Sanecka, Nagisa Yoshida, Elizabeth Motunrayo Kolawole, Harshil Patel, Brian D. Evavold, Eva-Maria Frickel

bioRxiv 263152; doi: https://doi.org/10.1101/263152

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Functional Improbable Antibody Mutations Critical for HIV Broadly Neutralizing Antibody Development
Kevin Wiehe, Todd Bradley, R. Ryan Meyerhoff, Connor Hart, Wilton Williams, David Easterhoff, William J. Faison, Thomas B. Kepler, Kevin Saunders, S. Munir Alam, Mattia Bonsignori, Barton F. Haynes

bioRxiv 262592; doi: https://doi.org/10.1101/262592

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Longitudinal immunosequencing in healthy people reveals persistent T cell receptors rich in public receptors
Nathaniel D. Chu, Haixin Sarah Bi, Ryan O. Emerson, Anna M. Sherwood, Michael E. Birnbaum, Harlan S. Robins, Eric J. Alm

bioRxiv 262667; doi: https://doi.org/10.1101/262667

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IFIT3 and IFIT2/3 promote IFIT1-mediated translation inhibition by enhancing binding to non-self RNA
Renata C Fleith, Harriet V Mears, Edward Emmott, Stephen C Graham, Daniel S Mansur, Trevor R Sweeney

bioRxiv 261776; doi: https://doi.org/10.1101/261776

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Influenza A Virus Negative Strand RNA is Translated for CD8+ T Cell Immunosurveillance
Heather D. Hickman, Jacqueline W. Mays, James Gibbs, Ivan Kosik, Javier Magadan, Kazuyo Takeda, Suman Das, Glennys V. Reynoso, Barbara F. Ngudiankama, JiaJie Wei, John P. Shannon, Daniel McManus, Jonathan W. Yewdell

bioRxiv 261966; doi: https://doi.org/10.1101/261966

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DPP9 is an endogenous and direct inhibitor of the NLRP1 inflammasome that guards against human auto-inflammatory diseases
Franklin L. Zhong, Kim Robinson, Chrissie Lim, Cassandra R. Harapas, Chien-Hsiung Yu, William Xie, Radoslaw M. Sobota, Veonice Bijin Au, Richard Hopkins, John E. Connolly, Seth Masters, Bruno Reversade

bioRxiv 260919; doi: https://doi.org/10.1101/260919

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Immunology

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