Immunology

B cells expressing authentic naive human VRC01-class BCRs can be primed and recruited to germinal centers in multiple independent mouse models
Deli Huang, Robert K. Abbott, Colin Havenar-Daughton, Patrick D. Skog, Rita Al-Kolla, Bettina Groschel, Tanya R. Blane, Sergey Menis, Jenny Tuyet Tran, Theresa C. Thinnes, Sabrina A. Volpi, Mark Pintea, James E Voss, Nicole Phelps, Ryan Tingle, Alberto R. Rodriguez, Greg Martin, Sergey Kupryianov, William R. Schief, David Nemazee, Shane Crotty

bioRxiv 2020.02.24.963629; doi: https://doi.org/10.1101/2020.02.24.963629

Add to Selected Citations
Epitope-based peptide vaccine design and target site characterization against novel coronavirus disease caused by SARS-CoV-2
Lin Li, Ting Sun, Yufei He, Wendong Li, Yubo Fan, Jing Zhang

bioRxiv 2020.02.25.965434; doi: https://doi.org/10.1101/2020.02.25.965434

Add to Selected Citations
Latent Plasticity of Effector-like Exhausted CD8 T cells contributes to memory responses
Saravanan Raju, Yu Xia, Bence Daniel, Kathryn E. Yost, Elliot Bradshaw, Elena Tonc, Daniel J. Verbaro, Ansuman T. Satpathy, Takeshi Egawa

bioRxiv 2020.02.22.960278; doi: https://doi.org/10.1101/2020.02.22.960278

Add to Selected Citations
A genome-wide CRISPR screen reveals a role for the BRD9-containing non-canonical BAF complex in regulatory T cells
Chin-San Loo, Jovylyn Gatchalian, Yuqiong Liang, Mathias Leblanc, Mingjun Xie, Josephine Ho, Bhargav Venkatraghavan, Diana C. Hargreaves, Ye Zheng

bioRxiv 2020.02.26.964981; doi: https://doi.org/10.1101/2020.02.26.964981

Add to Selected Citations
In silico design of Phl p 6 variants with altered folding stability significantly impacts antigen processing, immunogenicity and immune polarization
Petra Winter, Stefan Stubenvoll, Sandra Scheiblhofer, Isabella A Joubert, Lisa Strasser, Carolin Briganser, Soh Wai Tuck, Florian Hofer, Anna Sophia Kamenik, Valentin Dietrich, Sara Michelini, Josef Laimer, Peter Lackner, Jutta Horejs-Hoeck, Martin Tollinger, Klaus R. Liedl, Johann Brandstetter, Christian G. Huber, Weiss Richard

bioRxiv 2020.02.26.967265; doi: https://doi.org/10.1101/2020.02.26.967265

Add to Selected Citations
CRISPR Screen in Regulatory T Cells Reveals Ubiquitination Modulators of Foxp3
Jessica T. Cortez, Elena Montauti, Eric Shifrut, Yusi Zhang, Oren Shaked, Yuanming Xu, Theodore L. Roth, Dimitre R. Simeonov, Yana Zhang, Siqi Chen, Zhongmei Li, Ian A. Vogel, Grace Y. Prator, Bin Zhang, Youjin Lee, Zhaolin Sun, Igal Ifergan, Frédéric Van Gool, Jeffrey A. Bluestone, Alexander Marson, Deyu Fang

bioRxiv 2020.02.26.966911; doi: https://doi.org/10.1101/2020.02.26.966911

Add to Selected Citations
ICOS enhances follicular T helper responses and deteriorates the pathogenic process of liver in mice infected with Schistosoma japonicum
Bo Wang, Song Liang, Yan-Yan Wang, Yu Wang, Chao-Ming Xia

bioRxiv 2020.02.27.968248; doi: https://doi.org/10.1101/2020.02.27.968248

Add to Selected Citations
Resetting proteostasis with ISRIB prevents pulmonary fibrosis
Satoshi Watanabe, Nikolay S. Markov, Ziyan Lu, Raul Piseaux Aillon, Saul Soberanes, Constance E. Runyan, Ziyou Ren, Rogan A. Grant, Mariana Maciel, Hiam Abdala-Valencia, Yuliya Politanska, Kiwon Nam, Lango Sichizya, Hermon G. Kihshen, Nikita Joshi, Alexandra C. McQuattie-Pimentel, Richard I. Morimoto, Paul A. Reyfman, G.R. Scott Budinger, Alexander V. Misharin

bioRxiv 2020.02.26.965566; doi: https://doi.org/10.1101/2020.02.26.965566

Add to Selected Citations
Recreation of an antigen-driven germinal center in vitro by providing B cells with phagocytic antigen
Ana Martínez-Riaño, Pilar Delgado, Pilar Mendoza, Clara L. Oeste, David Abia, Elena Rodríguez-Bovolenta, Martin Turner, Balbino Alarcón

bioRxiv 2020.02.26.965921; doi: https://doi.org/10.1101/2020.02.26.965921

Add to Selected Citations
Dual functions of Aire CARD multimerization in the transcriptional regulation of T cell tolerance
Yu-San Huoh, Bin Wu, Sehoon Park, Darren Yang, Kushagra Bansal, Emily Greenwald, Wesley P. Wong, Diane Mathis, Sun Hur

bioRxiv 2020.02.26.966424; doi: https://doi.org/10.1101/2020.02.26.966424

Add to Selected Citations

Immunology

Pages