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Immunology

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  • MHC class II antigen presentation by intestinal epithelial cells fine-tunes bacteria-reactive CD4 T cell responses
    C. E. Heuberger, A. Janney, N. Ilott, A. Bertocchi, S. Pott, Y. Gu, M. Pohin, M. Friedrich, E. H. Mann, C. Pearson, F. M. Powrie, J. Pott, E. Thornton, K. J. Maloy
    bioRxiv 2023.01.23.525150; doi: https://doi.org/10.1101/2023.01.23.525150 New Results
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  • PNAG exopolysaccharide eradication gives neutrophils access to Staphylococcus aureus biofilm infections
    Rachel M. Kratofil, Trevor E. Randall, Josefien W. Hommes, Rehnuma Sejuty, Jessica Chisholm, Deepa Raju, Mario Vargas, P. Lynne Howell, Gerald B. Pier, Douglas W. Morck, Joe J. Harrison, Paul Kubes
    bioRxiv 2023.01.23.525131; doi: https://doi.org/10.1101/2023.01.23.525131 New Results
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  • Insm1 regulates the development of mTECs and immune tolerance
    Wehuai Tao, Yiqiu Wei, Zhihuan Ye, Jianxue Wang, Weixin Yang, Guoxing Yu, Jieyi Xiong, Shiqi Jia
    bioRxiv 2023.01.14.524041; doi: https://doi.org/10.1101/2023.01.14.524041 New Results
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  • New insights into the role of Cutibacterium acnes-derived extracellular vesicles in inflammatory skin disorders
    Maria Pol Cros, Júlia Mir-Pedrol, Lorena Toloza, Nastassia Knödlseder, Marc Güell, Julien Maruotti, Christos C. Zouboulis, Maria-José Fábrega Fernández
    bioRxiv 2022.12.15.520547; doi: https://doi.org/10.1101/2022.12.15.520547 New Results
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  • Cooperation between physiological defenses and immune resistance produces asymptomatic carriage of a lethal bacterial pathogen
    Grischa Y. Chen, Natalia R. Thorup, Abigail J. Miller, Yao-Cheng Li, Janelle S. Ayres
    bioRxiv 2023.01.22.525099; doi: https://doi.org/10.1101/2023.01.22.525099 New Results
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  • MEK1/2 inhibition decreases pro-inflammatory responses in macrophages from people with cystic fibrosis and mitigates severity of illness in experimental murine methicillin-resistant Staphylococcus aureus infection
    Mithu De, Katherine B. Hisert, W. Conrad Liles, Anne M. Manicone, Emily A. Hemann, Matthew E. Long
    bioRxiv 2023.01.22.525092; doi: https://doi.org/10.1101/2023.01.22.525092 New Results
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  • Knocking out CD70 rescues CD70-specific nanoCAR T cells from antigen induced exhaustion
    Stijn De Munter, Juliane Buhl, Laurenz De Cock, Alexander Van Parys, Willem Daneels, Eva Pascal, Lucas Deseins, Joline Ingels, Glenn Goetgeluk, Lore Billiet, Melissa Pille, Niels Vandamme, Jo Van Dorpe, Fritz Offner, Erik Depla, Jan Tavernier, Tessa Kerre, Jarno Drost, Bart Vandekerckhove
    bioRxiv 2023.01.22.523482; doi: https://doi.org/10.1101/2023.01.22.523482 New Results
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  • Single-cell and spatial multi-omics identify innate and stromal modules targeted by anti-integrin therapy in ulcerative colitis
    Elvira Mennillo, Yang Joon Kim, Iulia Rusu, Gyehyun Lee, Leah C. Dorman, Faviola Bernard-Vazquez, Jared L. Bain, Ravi Patel, Christopher Andersen, Arjun Rao, Stanley Tamaki, Jessica Tsui, Alan Shen, Mohammad Naser, Walter Eckalbar, Soo-jin Cho, Kendall Beck, Najwa El-Nachef, Sara Lewin, Daniel R Selvig, Jonathan P Terdiman, Uma Mahadevan, David Y. Oh, Gabriela K. Fragiadakis, Angela Pisco, Alexis J. Combes, Michael G. Kattah
    bioRxiv 2023.01.21.525036; doi: https://doi.org/10.1101/2023.01.21.525036 New Results
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  • Use of CD122+ natural killer cell precursors for superior anti-leukemia responses
    Silvia Guglietta, Luis Cardenas, Carsten Krieg
    bioRxiv 2022.10.24.513585; doi: https://doi.org/10.1101/2022.10.24.513585 New Results
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  • Keratinocytes coordinate inflammatory responses and regulate development of secondary lymphedema
    Hyeung Ju Park, Raghu P. Kataru, Jinyeon Shin, Gabriela D. García Nores, Elizabeth M. Encarnacion, Mark G. Klang, Elyn Riedel, Michelle Coriddi, Joseph H. Dayan, Babak J. Mehrara
    bioRxiv 2023.01.20.524936; doi: https://doi.org/10.1101/2023.01.20.524936 New Results
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