Molecular Biology

Endpoint PCR coupled with capillary electrophoresis (celPCR) provides sensitive and quantitative measures of environmental DNA in singleplex and multiplex reactions
Bettina Thalinger, Yannick Puetz, Michael Traugott

bioRxiv 2020.10.24.353730; doi: https://doi.org/10.1101/2020.10.24.353730 New Results

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SARS-CoV-2 RBD mutations, ACE2 genetic polymorphism, and stability of the virus-receptor complex: The COVID-19 host-pathogen nexus.
Dana Ashoor, Noureddine Ben Khalaf, Maryam Marzouq, Hamdi Jarjanazi, M. Dahmani Fathallah

bioRxiv 2020.10.23.352344; doi: https://doi.org/10.1101/2020.10.23.352344 New Results

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MicroRNA840 accelerates leaf senescence by targeting the overlapping 3'UTRs of PPR and WHIRLY3 in Arabidopsis
Yujun Ren, Wanzhen Wang, Wei Lan, Dirk Schenke, Daguang Cai, Ying Miao

bioRxiv 2020.10.23.353052; doi: https://doi.org/10.1101/2020.10.23.353052 New Results

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Biomolecular models of EPI-X4 binding to CXCR4 allow the rational optimization of peptides with therapeutic potential
Pandian Sokkar, Mirja Harms, Christina M Stuerzel, Andrea Gilg, Goenuel Kizilsavas, Martina Raasholm, Nico Preising, Manfred Wagner, Ludger Staendker, Gilbert Weidinger, Jan Muench, Elsa Sanchez-Garcia,

bioRxiv 2020.10.23.352708; doi: https://doi.org/10.1101/2020.10.23.352708 New Results

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One pathway, two cyclic pentapeptides: heterologous expression of BE-18257 A-C and pentaminomycins A-E from Streptomyces cacaoi CA-170360
Fernando Roman-Hurtado, Marina Sanchez-Hidalgo, Jesus Martin, Francisco Javier Ortiz-Lopez, Daniel Carretero-Molina, Fernando Reyes, Olga Genilloud

bioRxiv 2020.10.23.352575; doi: https://doi.org/10.1101/2020.10.23.352575 New Results

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Comprehensive deletion landscape of CRISPR-Cas9 identifies minimal RNA-guided DNA-binding modules
Arik Shams, Sean A Higgins, Christof Fellmann, Thomas G Laughlin, Benjamin L Oakes, Rachel Lew, Maria Lukarska, Madeline Arnold, Brett Staahl, Jennifer A Doudna, David F Savage

bioRxiv 2020.10.19.344077; doi: https://doi.org/10.1101/2020.10.19.344077 New Results

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Tracking pre-mRNA maturation across subcellular compartments identifies developmental gene regulation through intron retention and nuclear anchoring.
KYU-HYEON YEOM, Zhicheng Pan, Chia-Ho Lin, Wen Xiao, Hanyoung Lim, Yi Xing, Douglas L. Black

bioRxiv 2020.10.23.352088; doi: https://doi.org/10.1101/2020.10.23.352088 New Results

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Girding the loins? Direct evidence of the use of a medieval parchment birthing girdle from biomolecular analysis
Sarah Fiddyment, Natalie J Goodison, Elma Brenner, Stefania Signorello, Kierri Price, Matthew J Collins

bioRxiv 2020.10.21.348698; doi: https://doi.org/10.1101/2020.10.21.348698 New Results

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SARS-CoV-2 Nucleocapsid protein attenuates stress granule formation and alters gene expression via direct interaction with host mRNAs
Syed Nabeel-Shah, Hyunmin Lee, Nujhat Ahmed, Edyta Marcon, Shaghayegh Farhangmehr, Shuye Pu, Giovanni L Burke, Kanwal Ashraf, Hong Wei, Guoqing Zhong, Hua Tang, Jianyi Yang, Benjamin Blencowe, Zhaolei Zhang, Jack F Greenblatt

bioRxiv 2020.10.23.342113; doi: https://doi.org/10.1101/2020.10.23.342113 New Results

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Cardiovascular disease risk factors induce mesenchymal features and senescence in cardiac endothelial cells
Karthik Amudhala Hemanthakumar, Shentong Fang, Andrey Anisimov, Mikko I Mäyränpää, Eero Mervaala, Riikka Kivelä

bioRxiv 2020.10.21.349472; doi: https://doi.org/10.1101/2020.10.21.349472 New Results

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Molecular Biology

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