Molecular Biology

Transcriptomic profiling implicates PAF1 in both active and repressive immune regulatory networks
Matthew W. Kenaston, Oanh H. Pham, Marine J. Petit, Priya S. Shah

bioRxiv 2022.03.28.485548; doi: https://doi.org/10.1101/2022.03.28.485548 New Results

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CRISPR/Cas9-Mediated Excision of ALS/FTD-Causing Hexanucleotide Repeat Expansion in C9ORF72 rescues major disease mechanisms in vivo and in vitro
Katharina E. Meijboom, Abbas Abdallah, Nicholas P. Fordham, Hiroko Nagase, Tomás Rodriguez, Carolyn Kraus, Tania F. Gendron, Gopinath Krishnan, Rustam Esanov, Nadja S. Andrade, Matthew J. Rybin, Melina Ramic, Zachary D. Stephens, Alireza Edraki, Meghan T. Blackwood, Aydan Kahriman, Nils Henninger, Jean-Pierre A. Kocher, Michael Benatar, Michael H. Brodsky, Leonard Petrucelli, Fen-Biao Gao, Erik J. Sontheimer, Robert H. Brown, Zane Zeier, Christian Mueller

bioRxiv 2022.05.17.492303; doi: https://doi.org/10.1101/2022.05.17.492303 New Results

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RNA sequence to structure analysis from comprehensive pairwise mutagenesis of multiple self-cleaving ribozymes
Jessica M. Roberts, James D. Beck, Tanner B. Pollock, Devin P. Bendixsen, Eric J. Hayden

bioRxiv 2022.05.17.492349; doi: https://doi.org/10.1101/2022.05.17.492349 New Results

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In vitro and in vivo gene introduction in the cloudy catshark (Scyliorhinus torazame), a cartilaginous fish
Chika Fujimori, Chie Umatani, Misaki Chimura, Shigeho Ijiri, Hisanori Bando, Susumu Hyodo, Shinji Kanda

bioRxiv 2022.05.16.491766; doi: https://doi.org/10.1101/2022.05.16.491766 New Results

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Aberrant association of chromatin with nuclear periphery induced by Rif1 leads to mitotic defect and cell death
Yutaka Kanoh, Seiji Matsumoto, Masaru Ueno, Motoshi Hayano, Satomi Kudo, Hisao Masai

bioRxiv 2022.05.13.491604; doi: https://doi.org/10.1101/2022.05.13.491604 New Results

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Expression and subcellular localization of USH1C/harmonin in the human retina provide insights into pathomechanisms and therapy
Kerstin Nagel-Wolfrum, Benjamin R. Fadl, Mirjana M. Becker, Kirsten A. Wunderlich, Jessica Schäfer, Daniel Sturm, Jacques Fritze, Burcu Gür, Lew Kaplan, Tommaso Andreani, Tobias Goldmann, Matthew Brooks, Margaret R. Starostik, Anagha Lokhande, Melissa Apel, Karl R. Fath, Katarina Stingl, Susanne Kohl, Margaret M. DeAngelis, Ursula Schlötzer-Schrehardt, Ivana K. Kim, Leah A. Owen, Jan M. Vetter, Norbert Pfeiffer, Miguel A. Andrade-Navarro, Antje Grosche, Anand Swaroop, Uwe Wolfrum

bioRxiv 2021.08.27.457962; doi: https://doi.org/10.1101/2021.08.27.457962 New Results

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Three ALS genes regulate expression of the MHC class II antigen presentation pathway
Binkai Chi, Muhammet M. Öztürk, Christina L. Paraggio, Claudia E. Leonard, Maria E. Sanita, Mahtab Dastpak, Jeremy D. O’Connell, Jordan A. Coady, Jiuchun Zhang, Steven P. Gygi, Rodrigo Lopez-Gonzalez, Robin Reed

bioRxiv 2022.05.11.489680; doi: https://doi.org/10.1101/2022.05.11.489680 New Results

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siRNAs targeting a chromatin-associated RNA induce its transcriptional silencing in human cells
Julien Ouvrard, Lisa Muniz, Estelle Nicolas, Didier Trouche

bioRxiv 2022.05.11.491477; doi: https://doi.org/10.1101/2022.05.11.491477 New Results

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DNA double strand breaks lead to de novo transcription and translation of damage-induced long RNAs in planta
Tom Schreiber, Sunita Tripathee, Thomas Iwen, Anja Prange, Khabat Vahabi, Ramona Grützner, Claudia Horn, Sylvestre Marillonnet, Alain Tissier

bioRxiv 2022.05.11.491484; doi: https://doi.org/10.1101/2022.05.11.491484 New Results

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Glucose-regulated O-GlcNAcylation of DNMT1 inhibits DNA methyltransferase activity and maintenance of genomic methylation
Heon Shin, Amy Leung, Kevin R. Costello, Parijat Senapati, Hiroyuki Kato, Dustin E. Schones

bioRxiv 2022.05.11.491514; doi: https://doi.org/10.1101/2022.05.11.491514 New Results

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Molecular Biology

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