Molecular Biology

The AGE receptor, OST48 drives podocyte foot process effacement and basement membrane expansion in experimental diabetic kidney disease via promotion of endoplasmic reticulum stress
Aowen Zhuang, Felicia YT Yap, Domenica McCarthy, Sally A Penfold, Karly C Sourris, Melinda T Coughlan, Benjamin L Schulz, Josephine M Forbes

bioRxiv 710186; doi: https://doi.org/10.1101/710186 New Results

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Cardiac nitric oxide synthase 1 worsens heart failure with preserved ejection fraction through S-nitrosylation of histone deacetylase 2
Somy Yoon, Mira Kim, Hangyeol Lee, Gaeun Kang, Kwang Il Nam, Hyun Kook, Gwang Hyeon Eom

bioRxiv 708297; doi: https://doi.org/10.1101/708297 New Results

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Genome-wide survey of ribosome collision
Peixun Han, Mari Mito, Yuichi Shichino, Satoshi Hashimoto, Tsuyoshi Udagawa, Kenji Kohno, Yuichiro Mishima, Toshifumi Inada, Shintaro Iwasaki

bioRxiv 710491; doi: https://doi.org/10.1101/710491 New Results

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Globally elevating the AGE clearance receptor, OST48, does not protect against the development of diabetic kidney disease, despite improving insulin secretion.
Aowen Zhuang, Felicia YT Yap, Domenica McCarthy, Sherman S Leung, Sally A Penfold, Chris Leung, Karly C Sourris, Brooke Harcourt, Vicki Thallas-Bonke, Melinda T Coughlan, Benjamin Schulz, Josephine Forbes

bioRxiv 710558; doi: https://doi.org/10.1101/710558 New Results

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The Histone H3-H4 Tetramer is a Copper Reductase Enzyme
Narsis Attar, Oscar A Campos, Maria Vogelauer, Chen Cheng, Yong Xue, Stefan Schmollinger, Nathan V Mallipeddi, Brandon A Boone, Linda Yen, Sichen Yang, Shannon Zikovich, Jade Dardine, Michael F Carey, Sabeeha S Merchant, Siavash K Kurdistani

bioRxiv 350652; doi: https://doi.org/10.1101/350652 New Results

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Exploring the basis of 2-propenyl and 3-butenyl glucosinolate synthesis by QTL mapping and RNA-sequencing in Brassica juncea
Aimal Nawaz Khattak, Tianya Wang, Kunjiang Yu, Renqin Yang, Wei Wan, Botao Ye, Entang Tian

bioRxiv 711044; doi: https://doi.org/10.1101/711044 New Results

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Mlh1 haploinsufficiency induces microsatellite instability specifically in intestine
Kul S. Shrestha, Minna M. Tuominen, Liisa Kauppi

bioRxiv 652198; doi: https://doi.org/10.1101/652198 New Results

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The sequential and cooperative action of CSB, CSA and UVSSA targets the TFIIH complex to DNA damage-stalled RNA polymerase II
Yana van der Weegen, Hadar Golan Berman, Tycho E.T. Mevissen, Katja Apelt, Román González-Prieto, Elisheva Heilbrun, Alfred C.O. Vertegaal, Diana van den Heuvel, Johannes C. Walter, Sheera Adar, Martijn S. Luijsterburg

bioRxiv 707216; doi: https://doi.org/10.1101/707216 New Results

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RNA processing machineries in Archaea: the 5’-3’ exoribonuclease aRNase J of the β-CASP family is engaged specifically with the helicase ASH-Ski2 and the 3’-5’ exoribonucleolytic RNA exosome machinery
Duy Khanh Phung, Clarisse Etienne, Manon Batista, Petra Langendijk-Genevaux, Yann Moalic, Sébastien Laurent, Violette Morales, Mohamed Jebbar, Gwennaele Fichant, Marie Bouvier, Didier Flament, Béatrice Clouet-d’Orval

bioRxiv 699629; doi: https://doi.org/10.1101/699629 New Results

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A conserved SUMO-Ubiquitin pathway directed by RNF4/SLX5-SLX8 and PIAS4/SIZ1 drives proteasomal degradation of topoisomerase DNA-protein crosslinks
Yilun Sun, Lisa M. Miller Jenkins, Yijun P. Su, Karin C. Nitiss, John L. Nitiss, Yves Pommier

bioRxiv 707661; doi: https://doi.org/10.1101/707661 New Results

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Molecular Biology

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