Molecular Biology

Saracatinib is an efficacious clinical candidate for fibrodysplasia ossificans progressiva
Eleanor Williams, Jana Bagarova, Georgina Kerr, Dong-Dong Xia, Elsie S Place, Devaveena Dey, Yue Shen, Geoffrey A Bocobo, Agustin H Mohedas, Xiuli Huang, Philip E Sanderson, Arthur Lee, Wei Zheng, Aris N Economides, James C Smith, Paul B Yu, Alex N Bullock

bioRxiv 2020.10.29.360370; doi: https://doi.org/10.1101/2020.10.29.360370 New Results

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Promotion of USP4 to TGF-β1-induced EMT in renal tubular epithelial cells is regulated by Akt through stabilizing TβRI
Jinyun Pu, Jianhua Zhou

bioRxiv 2020.10.28.358796; doi: https://doi.org/10.1101/2020.10.28.358796 New Results

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High dose IFN-β activates GAF to enhance expression of ISGF3 target genes in epithelial cells
Kensei Kishimoto, Catera Wilder, Justin Buchanan, Minh Nguyen, Chidera Okeke, Alexander Hoffmann, Quen J Cheng

bioRxiv 2020.10.28.358366; doi: https://doi.org/10.1101/2020.10.28.358366 New Results

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Gene replacement of α-globin with β-globin restores hemoglobin balance in β-thalassemia-derived hematopoietic stem and progenitor cells
M. Kyle Cromer, Joab Camarena, Renata M. Martin, Benjamin J. Lesch, Christopher A. Vakulskas, Viktor T. Lemgart, Yankai Zhang, Ankush Goyal, Feifei Zhao, Ezequiel Ponce, Wai Srifa, Rasmus O. Bak, Naoya Uchida, Ravindra Majeti, Vivien A. Sheehan, John F. Tisdale, Daniel P. Dever, Matthew Porteus

bioRxiv 2020.10.28.359315; doi: https://doi.org/10.1101/2020.10.28.359315 New Results

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Modulating Intra-Nuclear LC3 with Small Molecules Rescues Cells from a Docetaxel-Induced Phenotype
Daniel P Rosenberg, Likhitha Kolla, David Heo, Emily Cassio, Matthew J Veenstra, Maria Vakaki, Jibo Zhang, Cyril Anyetei-Anum, Lizabeth A Allison, William J Buchser

bioRxiv 2020.10.28.355826; doi: https://doi.org/10.1101/2020.10.28.355826 New Results

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Repeat DNA-PAINT suppresses background and non-specific signals in optical nanoscopy
Alexander H Clowsley, William T Kaufhold, Tobias Lutz, Anna Meletiou, Lorenzo Di Michele, Christian Soeller

bioRxiv 2020.04.24.059410; doi: https://doi.org/10.1101/2020.04.24.059410 New Results

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Suppressing STAT3 activity protects the endothelial barrier from VEGF-mediated vascular permeability
Li Wang, Matteo Astone, Sk. Kayum Alam, Zhu Zhu, Wuhong Pei, David A. Frank, Shawn M. Burgess, Luke H. Hoeppner

bioRxiv 2020.10.27.358374; doi: https://doi.org/10.1101/2020.10.27.358374 New Results

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Structural differences in translation initiation between pathogenic trypanosomatids and their mammalian hosts
Anthony Bochler, Jailson Brito Querido, Terezie Prilepskaja, Heddy Soufari, Angelita Simonetti, Mayara Lucia Del Cistia, Lauriane Kuhn, Aline Rimoldi Ribeiro, Leoš Shivaya Valášek, Yaser Hashem

bioRxiv 806141; doi: https://doi.org/10.1101/806141 New Results

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Poly-ADP-ribosylation drives loss of protein homeostasis in ATM and Mre11 deficiency
Ji-Hoon Lee, Seung W. Ryu, Nicolette A. Ender, Tanya T. Paull

bioRxiv 2020.10.27.357210; doi: https://doi.org/10.1101/2020.10.27.357210 New Results

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Chimeric single α-helical domains as rigid fusion protein connections for protein nanotechnology and structural biology
Gabriella Collu, Tobias Bierig, Anna-Sophia Krebs, Sylvain Engilberge, Niveditha Varma, Ramon Guixà-González, Xavier Deupi, Vincent Olieric, Emiliya Poghosyan, Roger M. Benoit

bioRxiv 2020.09.29.318410; doi: https://doi.org/10.1101/2020.09.29.318410 New Results

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Molecular Biology

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