Molecular Biology

Both Determinants of Allosteric and Active Sites Responsible for Catalytic Activity of Delta 12 Fatty Acid Desaturase by Domain Swapping
Haisu Shi, Jinlong Tian, Chen Wu, Mo Li, Feiyu An, Rina Wu, Junhua Shao, Yan Zheng, Xue Luo, Dongbing Tao, Xu Chen, Yuzhen Pi, Chunyan Zhao, Xiqing Yue, Junrui Wu

bioRxiv 789503; doi: https://doi.org/10.1101/789503 New Results

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Thermodynamic destabilization informs pathogenicity assessment of a variant of uncertain significance in cardiac myosin binding protein C
Maria Rosaria Pricolo, Elías Herrero-Galán, Cristina Mazzaccara, Maria Angela Losi, Jorge Alegre-Cebollada, Giulia Frisso

bioRxiv 789081; doi: https://doi.org/10.1101/789081 New Results

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Regulation of transcription termination by FUS and TDP-43
Dorothy Yanling Zhao, Zuyao Ni, Shuye Pu, Guoqing Zhong, Frank W. Schmitges, Ulrich Braunschweig, Benjamin J. Blencowe, Jack F. Greenblatt

bioRxiv 788778; doi: https://doi.org/10.1101/788778 New Results

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The retinoblastoma tumor suppressor limits ribosomal readthrough during oncogene induced senescence
Neylen del Toro, Frédéric Lessard, Sarah Tardif, Jacob Bouchard, Véronique Bourdeau, Gerardo Ferbeyre, Léa Brakier-Gingras

bioRxiv 788380; doi: https://doi.org/10.1101/788380 New Results

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A Long Lost Key Opens an Ancient Lock: Drosophila Myb Causes a Synthetic Multivulval Phenotype in Nematodes
Paul Vorster, Paul Goetsch, Tilini U. Wijeratne, Keelan Z. Guiley, Laura Andrejka, Sarvind Tripathi, Braden J. Larson, Seth M. Rubin, Susan Strome, Joseph S. Lipsick

bioRxiv 788265; doi: https://doi.org/10.1101/788265 New Results

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Cell-specific targeting by Clostridium perfringens β-toxin unraveled: the role of CD31 as the toxin receptor
Julia Bruggisser, Basma Tarek, Marianne Wyder, Guillaume Witz, Gaby Enzmann, Urban Deutsch, Britta Engelhardt, Horst Posthaus

bioRxiv 787242; doi: https://doi.org/10.1101/787242 New Results

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MicroRNA-27a is a key modulator of cholesterol biosynthesis
Abrar A. Khan, Heena Agarwal, S. Santosh Reddy, Vikas Arige, Vinayak Gupta, Ananthamohan Kalyani, Manoj K. Barthwal, Nitish R. Mahapatra

bioRxiv 383448; doi: https://doi.org/10.1101/383448 New Results

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Examining multiple cellular pathways at once using multiplex hextuple luciferase assaying
Alejandro Sarrion-Perdigones, Lyra Chang, Yezabel Gonzalez, Tatiana Gallego-Flores, Damian W. Young, Koen J.T. Venken

bioRxiv 786046; doi: https://doi.org/10.1101/786046 New Results

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The majority of histone acetylation is a consequence of transcription
Benjamin J.E. Martin, Julie Brind’Amour, Kristoffer N. Jensen, Anastasia Kuzmin, Zhen Cheng Liu, Matthew Lorincz, LeAnn J. Howe

bioRxiv 785998; doi: https://doi.org/10.1101/785998 New Results

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Structural consequences of BMPR2 kinase domain mutations causing pulmonary arterial hypertension
Apirat Chaikuad, Chancievan Thangaratnarajah, Frank von Delft, Alex N Bullock

bioRxiv 786756; doi: https://doi.org/10.1101/786756 New Results

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Molecular Biology

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