Molecular Biology

MTALTCO1: a 259 amino-acid long mtDNA-encoded alternative protein that challenges conventional understandings of mitochondrial genomics
Francis Robitaille, Aziz Ben Hadj, Amy Campbell, Ludovic Nadeau-Lachance, Thierry Niaison, Thierry Choquette, Xavier Roucou, Annie Angers, Sophie Breton

bioRxiv 2024.09.22.614361; doi: https://doi.org/10.1101/2024.09.22.614361 New Results

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Interaction between histone residue H3K56 and mismatch repair protein MutSβ drives CAG repeat expansion
Jinzhen Guo, Wei Yang, Guo-Min Li

bioRxiv 2024.09.29.615664; doi: https://doi.org/10.1101/2024.09.29.615664 New Results

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VirtualIce: Half-synthetic CryoEM Micrograph Generator
Alex J. Noble

bioRxiv 2024.09.28.615520; doi: https://doi.org/10.1101/2024.09.28.615520 New Results

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Mechanistic Insights into the Stimulation of the Histone H3K9 Methyltransferase Clr4 by Proximal H3K14 Ubiquitination
Yunxiang Du, Maoshen Sun, Zhengqing Li, Xiangwei Wu, Qian Qu, Huasong Ai, Lei Liu

bioRxiv 2024.09.28.615623; doi: https://doi.org/10.1101/2024.09.28.615623 New Results

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Loss of Ing4 enhances hematopoietic regeneration in multipotent progenitor cells
Georgina A. Anderson, Marco Hernandez, Carlos Alfaro Quinde, Zanshé Thompson, Melanie Rodriguez, Vera Binder-Blaser, Alison M. Taylor, Katie L. Kathrein

bioRxiv 2024.09.27.615522; doi: https://doi.org/10.1101/2024.09.27.615522 New Results

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Megabase-scale loss of heterozygosity provoked by CRISPR-Cas9 DNA double-strand breaks
Samantha B. Regan, Darpan Medhi, Travis B. White, Yi-Zhen Jiang, Su Jia, Qichen Deng, Maria Jasin

bioRxiv 2024.09.27.615517; doi: https://doi.org/10.1101/2024.09.27.615517 New Results

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Potent and Selective SETDB1 Covalent Negative Allosteric Modulator Reduces Methyltransferase Activity in Cells
Mélanie Uguen, Devan J. Shell, Madhushika Silva, Yu Deng, Fengling Li, Magdalena M. Szewczyk, Ka Yang, Yani Zhao, Michael A. Stashko, Jacqueline L. Norris-Drouin, Jarod M. Waybright, Serap Beldar, Justin M. Rectenwald, Angie L. Mordant, Thomas S. Webb, Laura E. Herring, Cheryl H. Arrowsmith, Suzanne Ackloo, Steven P. Gygi, Robert K. McGinty, Dalia Barsyte-Lovejoy, Pengda Liu, Levon Halabelian, Lindsey I. James, Kenneth H. Pearce, Stephen V. Frye

bioRxiv 2024.09.27.615363; doi: https://doi.org/10.1101/2024.09.27.615363 New Results

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AAV9-mediated targeting of natural antisense transcript as a novel treatment for Dravet Syndrome
Juan Antinao Diaz, Ellie Chilcott, Amanda Almacellas Barbanoj, Anna Keegan, Amy McTague, J Helen Cross, Stephanie Schorge, Gabriele Lignani, Simon Nicholas Waddington, Rajvinder Karda

bioRxiv 2024.09.27.615323; doi: https://doi.org/10.1101/2024.09.27.615323 New Results

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irCLIP-RNP and Re-CLIP reveal patterns of dynamic protein associations on RNA
Luca Ducoli, Brian J. Zarnegar, Douglas F. Porter, Robin M. Meyers, Weili Miao, Nicholas M. Riley, Suhas Srinivasan, Leandra V. Jackrazi, Yen-Yu Yang, Zhouxian Li, Yinsheng Wang, Carolyn R. Bertozzi, Ryan A. Flynn, Paul A. Khavari

bioRxiv 2024.09.27.615518; doi: https://doi.org/10.1101/2024.09.27.615518 New Results

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Mitotic chromatin marking governs asymmetric segregation of DNA damage
Juliette Ferrand, Juliette Dabin, Odile Chevallier, Matteo Kane-Charvin, Ariana Kupai, Joel Hrit, Scott B. Rothbart, Sophie E. Polo

bioRxiv 2023.09.04.556166; doi: https://doi.org/10.1101/2023.09.04.556166 New Results

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Molecular Biology

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