Pathology

Modeling of fibrotic lung disease using 3D organoids derived from human pluripotent stem cells
Hans-Willem Snoeck, Alexandros Strikoudis, Lucas Loffredo, Ya-Wen Chen

bioRxiv 538991; doi: https://doi.org/10.1101/538991 New Results
Cerebral Ischemic-Hypoxia Induces TRPC6 in the Glomerular Podocytes: A Novel Role for HIF1α-ZEB2 Axis in the Pathogenesis of Stroke-induced Proteinuria
Krishnamurthy Nakuluri, Rajkishor Nishad, Dhanunjay Mukhi, Sireesh K Teertam, Venkata P Nakka, Parimala Narne, Sai Sampath K Natuva, Prakash Babu Phanithi, Anil K Pasupulati

bioRxiv 538959; doi: https://doi.org/10.1101/538959 New Results
Alzheimer's disease clinical variants show distinct regional patterns of neurofibrillary tangle accumulation
Cathrine Petersen, Amber L. Nolan, Elisa de Paula Franca Resende, Alexander J. Ehrenberg, Salvatore Spina, Bruce L. Miller, William Seeley, Zachary Miller, Lea Grinberg

bioRxiv 538496; doi: https://doi.org/10.1101/538496 New Results
Proteolytic program-dependent functions are impaired in INF2-mediated focal segmental glomerulosclerosis.
Balaji Karthick Subramanian, Justin Chun, Chandra Perez, Paul Yan, Isaac Stillman, Henry Higgs, Seth Alper, Johannes Schlondorff, Martin Pollak

bioRxiv 530642; doi: https://doi.org/10.1101/530642 New Results
Classifying Non-Small Cell Lung Cancer Histopathology Types and Transcriptomic Subtypes using Convolutional Neural Networks
Kun-Hsing Yu, Feiran Wang, Gerald J. Berry, Christopher Re, Russ B. Altman, Michael Snyder, Isaac S. Kohane

bioRxiv 530360; doi: https://doi.org/10.1101/530360 New Results
Hepatocyte-specific deletion of Pparα promotes NASH in the context of obesity
Marion Regnier, Arnaud Polizzi, Sarra Smati, Celine Lukowicz, Anne Fougerat, Yannick Lippi, Edwin Fouche, Frederic Lasserre, Claire Naylies, Colette Betoulieres, Valentin Barquissau, Etienne Mouisel, Justine Bertrand-Michel, Aurelie Batut, Talal Al Saati, Cecile Canlet, Marie Tremblay-Franco, Sandrine Ellero-Simatos, Dominique Langin, Catherine Postic, Walter Wahli, Nicolas Loiseau, Herve Guillou, Alexandra Montagner

bioRxiv 488031; doi: https://doi.org/10.1101/488031 New Results
A multimodal approach to identify clinically relevant parameters to monitor disease progression in a preclinical model of neuropediatric disease
Tyler B Johnson, Jon J Brudvig, Kimmo K Lehtimäki, Jacob T Cain, Katherine A White, Timo Bragge, Jussi Rytkönen, Tuulia Huhtala, Derek Timm, Maria Vihma, Jukka T Puoliväli, Antti Nurmi, Jill M Weimer

bioRxiv 522011; doi: https://doi.org/10.1101/522011 New Results
Hippocampal morphometry in sudden and unexpected death in epilepsy (SUDEP)
Alyma Somani, Anita-Beatrix Zborovschi, Yan Liu, Smriti Patodia, Zuzanna Michalak, Sanjay Sisodiya, Maria Thom

bioRxiv 522300; doi: https://doi.org/10.1101/522300 New Results
Age-dependent characterization of the carotid and cerebral artery morphologies in a transgenic mouse model of sickle cell anemia using ultrasound and microcomputed tomography
Christian P Rivera, Li Li, Shuangyi Cai, Nui Pei, George McAlear, Keval Bollavaram, Oluwasanmi V Ariyo, Victor O Omojola, Hannah Song, Wenchang Tan, Yunlong Huo, Manu O Platt

bioRxiv 522748; doi: https://doi.org/10.1101/522748 New Results
A Zika vaccine based on chimpanzee adenovirus ChAdOx1 elicits lineage-transcending sterile immunity and prevents colonisation of brain and ovaries
Cesar Lopez-Camacho, Stuart Dowall, Victoria Graham, Stephen Findlay-Wilson, Emma Rayner, Young Chan Kim, Roger Hewson, Arturo Reyes-Sandoval

bioRxiv 514877; doi: https://doi.org/10.1101/514877 New Results

Pathology

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