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Pathology

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  • FGF21 protects against hepatic lipotoxicity and macrophage activation to attenuate fibrogenesis in nonalcoholic steatohepatitis
    Cong Liu, Milena Schönke, Borah Spoorenberg, Joost M. Lambooij, Hendrik J.P. van der Zande, Enchen Zhou, Maarten E. Tushuizen, Anne-Christine Andréasson, Andrew Park, Stephanie Oldham, Martin Uhrbom, Ingela Ahlstedt, Yasuhiro Ikeda, Kristina Wallenius, Xiao-Rong Peng, Bruno Guigas, Mariëtte R. Boon, Yanan Wang, Patrick C.N. Rensen
    bioRxiv 2022.09.20.508654; doi: https://doi.org/10.1101/2022.09.20.508654
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  • Continuous Hypoxia Reduces Retinal Ganglion Cell Degeneration in a Mouse Model of Mitochondrial Optic Neuropathy
    Alexander M. Warwick, Howard M. Bomze, Luyu Wang, Mikael Klingeborn, Ying Hao, Sandra S. Stinnett, Sidney M. Gospe III
    bioRxiv 2022.09.15.508111; doi: https://doi.org/10.1101/2022.09.15.508111
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  • Dimethyl fumarate modulates the Duchenne muscular dystrophy disease program following short-term treatment in mdx mice
    Cara A. Timpani, Stephanie Kourakis, Danielle A. Debruin, Dean G. Campelj, Nancy Pompeani, Narges Dargahi, Angelo P. Bautista, Ryan M. Bagaric, Elya J. Ritenis, Lauren Sahakian, Patricia Hafner, Peter G. Arthur, Jessica R. Terrill, Vasso Apostolopoulos, Judy B. de Haan, Nuri Guven, Dirk Fischer, Emma Rybalka
    bioRxiv 2022.09.15.508124; doi: https://doi.org/10.1101/2022.09.15.508124
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  • Inflammation-mediated Upregulation of VCAM-1 but not KIM-1 during Acute Kidney Injury to Chronic Kidney Disease Transition
    Isabel Melchinger, Kailin Guo, Jiankan Guo, Leyuan Xu
    bioRxiv 2022.09.15.508151; doi: https://doi.org/10.1101/2022.09.15.508151
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  • Pathology of African Swine Fever in wild boar naturally infected with German virus variants
    Julia Sehl-Ewert, Paul Deutschmann, Angele Breithaupt, Sandra Blome
    bioRxiv 2022.09.14.507889; doi: https://doi.org/10.1101/2022.09.14.507889
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  • Involvement of an IgE/Mast cell/B cell amplification loop in abdominal aortic aneurysm progression
    Alexia Loste, Marc Clément, Sandrine Delbosc, Kevin Guedj, Jean Sénémaud, Anh-Thu Gaston, Marion Morvan, Guillaume Even, Grégory Gautier, Alexander Eggel, Michel Arock, Emanuele Procopio, Catherine Deschildre, Liliane Louedec, Jean-Baptiste Michel, Lydia Deschamps, Yves Castier, Raphaël Coscas, Jean-Marc Alsac, Pierre Launay, Giuseppina Caligiuri, Antonino Nicoletti, Marie Le Borgne
    bioRxiv 2022.09.13.507783; doi: https://doi.org/10.1101/2022.09.13.507783
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  • (Pro)Renin Receptor Antagonism Attenuates High-Fat-Diet–Induced Hepatic Steatosis in Non-Alcoholic Fatty Liver Disease
    Ariana Julia B. Gayban, Lucas Souza, Silvana G. Cooper, Erick Regalado, Robert Kleemann, Yumei Feng Earley
    bioRxiv 2022.09.07.506819; doi: https://doi.org/10.1101/2022.09.07.506819
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  • Hepatic fibrosis induced zinc-deficient dermatosis in American alligators (Alligator mississippiensis)
    Ilaria M. Piras, Annemarie Bezuidenhout, Josué Díaz-Delgado, Deirdre Slawski, Pamela A. Kelly
    bioRxiv 2022.08.30.505809; doi: https://doi.org/10.1101/2022.08.30.505809
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  • GDF15 antagonism limits severe heart failure and prevents cardiac cachexia in mice
    Minoru Takaoka, John A. Tadross, Ali Al-Hadithi, Rocío Villena-Gutiérrez, Jasper Tromp, Shazia Absar, Marcus Au, James Harrison, P. Coll Anthony, Stefan J. Marciniak, Debra Rimmington, Eduardo Oliver, Borja Ibáñez, A. Voors Adriaan, Stephen O’Rahilly, Ziad Mallat, Jane C. Goodall
    bioRxiv 2022.09.06.506633; doi: https://doi.org/10.1101/2022.09.06.506633
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  • Investigating the risk of cardiac fibrosis due to heat-not-burn cigarettes through human cardiac stromal cells
    Vittorio Picchio, Francesca Pagano, Roberto Carnevale, Alessandra D’Amico, Claudia Cozzolino, Erica Floris, Antonella Bordin, Leonardo Schirone, Wael Saade, Fabio Miraldi, Elena De Falco, Sebastiano Sciarretta, Mariangela Peruzzi, Giuseppe Biondi-Zoccai, Giacomo Frati, Isotta Chimenti
    bioRxiv 2022.09.06.506632; doi: https://doi.org/10.1101/2022.09.06.506632
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