Pathology

EPAC1 inhibition protects the heart from doxorubicin-induced toxicity
Marianne Mazevet, Anissa Belhadef, Maxance Ribeiro, Delphine Dayde, Anna Llach, Marion Laudette, Tiphaine Belleville, Philippe Mateo, Mélanie Gressette, Florence Lefebvre, Ju Chen, Christilla Bachelot-Loza, Catherine Rucker-Martin, Frank Lezoualc’h, Bertrand Crozatier, Jean-Pierre Benitah, Marie-Catherine Vozenin, Rodolphe Fischmeister, Ana-Maria Gomez, Christophe Lemaire, Eric Morel

bioRxiv 2021.06.16.448655; doi: https://doi.org/10.1101/2021.06.16.448655

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Epsin2, a novel target for multiple system atrophy therapy via α-synuclein/FABP7 propagation
An Cheng, Ichiro Kawahata, Yifei Wang, Wenbin Jia, Tomoki Sekimori, Yi Chen, Nadia Stefanova, David I Finkelstein, Wenbo Ma, Min Chen, Takuya Sasaki, Kohji Fukunaga

bioRxiv 2022.06.16.496509; doi: https://doi.org/10.1101/2022.06.16.496509

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Antiretroviral Therapy Does Not Restore Brain Lipids During SIV Infection: Regional Analysis of Metabolic Homeostasis and Depletion
Cory J. White, Andrew M. Gausepohl, Herana Kamal Seneviratne, Namandjé N. Bumpus, Dionna W. Williams

bioRxiv 2022.09.26.508302; doi: https://doi.org/10.1101/2022.09.26.508302

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Spatial transcriptomic profiling of coronary endothelial cells in SARS-CoV-2 myocarditis
Camilla Margaroli, Paul Benson, Maria G Gastanadui, Chunyan Song, Liliana Viera, Dongqi Xing, J. Michael Wells, Rakesh Patel, Amit Gaggar, Gregory A. Payne

bioRxiv 2022.09.25.509426; doi: https://doi.org/10.1101/2022.09.25.509426

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Multiplatform Modeling of Atrial Fibrillation Identifies Phospholamban as Central Regulator of Cardiac Rhythm
Anaïs Kervadec, James Kezos, Haibo Ni, Michael Yu, Sean Spiering, Suraj Kannan, Peter Andersen, Eleonora Grandi, Karen Ocorr, Alexandre R. Colas

bioRxiv 2022.09.23.509238; doi: https://doi.org/10.1101/2022.09.23.509238

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A Murine Model of Abductor Insufficiency Accelerates the Development of Hip Osteoarthritis
Michael B. Geary, Caitlin A. Orner, Helen Shammas, John M. Reuter, Alayna E. Loiselle, Chia-Lung Wu, Brian D. Giordano

bioRxiv 2022.05.22.492940; doi: https://doi.org/10.1101/2022.05.22.492940

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In situ single-cell analysis of canonical breast cancer biomarkers: phenotypic heterogeneity and implications on response to HER2 targeting agents
Garazi Serna, Eloy García, Roberta Fasani, Xavier Guardia, Tomas Pascual, Laia Paré, Fiorella Ruiz-Pace, Antonio Llombart-Cussac, Javier Cortes, Aleix Prat, Paolo Nuciforo

bioRxiv 2022.09.21.508826; doi: https://doi.org/10.1101/2022.09.21.508826

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Single cell genotypic and phenotypic analysis of measurable residual disease in acute myeloid leukemia
Troy M. Robinson, Robert L. Bowman, Sonali Persaud, Ying Liu, Qi Gao, Jingping Zhang, Xiaotian Sun, Linde A. Miles, Sheng F. Cai, Adam Sciambi, Aaron Llanso, Christopher Famulare, Aaron Goldberg, Ahmet Dogan, Mikhail Roshal, Ross L. Levine, Wenbin Xiao

bioRxiv 2022.09.20.508786; doi: https://doi.org/10.1101/2022.09.20.508786

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FGF21 protects against hepatic lipotoxicity and macrophage activation to attenuate fibrogenesis in nonalcoholic steatohepatitis
Cong Liu, Milena Schönke, Borah Spoorenberg, Joost M. Lambooij, Hendrik J.P. van der Zande, Enchen Zhou, Maarten E. Tushuizen, Anne-Christine Andréasson, Andrew Park, Stephanie Oldham, Martin Uhrbom, Ingela Ahlstedt, Yasuhiro Ikeda, Kristina Wallenius, Xiao-Rong Peng, Bruno Guigas, Mariëtte R. Boon, Yanan Wang, Patrick C.N. Rensen

bioRxiv 2022.09.20.508654; doi: https://doi.org/10.1101/2022.09.20.508654

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Continuous Hypoxia Reduces Retinal Ganglion Cell Degeneration in a Mouse Model of Mitochondrial Optic Neuropathy
Alexander M. Warwick, Howard M. Bomze, Luyu Wang, Mikael Klingeborn, Ying Hao, Sandra S. Stinnett, Sidney M. Gospe III

bioRxiv 2022.09.15.508111; doi: https://doi.org/10.1101/2022.09.15.508111

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Pathology

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