Pharmacology and Toxicology

Identification of Kinase Inhibitors that Regulate Nuclear Receptor Nurr1 (NR4A2) Cellular Activity
Kenya L. Williams, Carrow I. Wells, John T. Moore

bioRxiv 420976; doi: https://doi.org/10.1101/420976 New Results
Honey bee workers reared in a neonicotinoid contaminated in-hive environment
Richard Odemer, Franziska Odemer

bioRxiv 420919; doi: https://doi.org/10.1101/420919 Confirmatory Results
The in vitro toxicity of nitrile and epithionitrile derivatives of glucosinolates from rutabaga in human and bovine liver cells.
Ian Latimer, Mark Collett, Zoe Matthews, Brian Tapper, Belinda Cridge

bioRxiv 419960; doi: https://doi.org/10.1101/419960 New Results
Effects of Nicotine and THC Vapor Inhalation Administered by An Electronic Nicotine Delivery System (ENDS) in Male Rats
Mehrak Javadi-Paydar, Maury Cole, Michael A Taffe

bioRxiv 418699; doi: https://doi.org/10.1101/418699 New Results
T vector velocity: A new ECG biomarker for identifying drug effects on cardiac ventricular repolarization
Werner Bystricky, Christoph Maier, Gary Gintant, Dennis Bergau, Kent Kamradt, Patrick Welsh, David Carter

bioRxiv 418277; doi: https://doi.org/10.1101/418277 New Results
Identification and Quantification of Paclitaxel and its Metabolites in Human Meconium from Newborns with Gestational Chemotherapeutic Exposure
Elyce Cardonick, Robert Broadrup, Peining Xu, Mary T. Doan, Helen Jiang, Nathaniel Snyder

bioRxiv 306274; doi: https://doi.org/10.1101/306274 New Results
Esterase Activity is Affected by Genetics, Age, Insecticide Exposure, and Viral Infection in the Honey Bee, Apis mellifera
Frank D. Rinkevich, Joseph W Margotta, Michael Simone-Finstrom, Lilia I De Guzman, Kristen B Healy

bioRxiv 415356; doi: https://doi.org/10.1101/415356 New Results
The Utilization of Pharmacophore-based 3D QSAR Modeling and Virtual Screening in Safety Profiling: a Case Study to Identify Antagonistic Activities against Adenosince Receptor, A2aR, using 1,897 known drugs
Fan Fan, Hisham Hamadeh, Dora Toledo Warshaviak, Robert Dunn

bioRxiv 413385; doi: https://doi.org/10.1101/413385 New Results
Primary Target Prediction of Bioactive Molecules from Chemical Structure
Abed Forouzesh, Sadegh Samadi Foroushani, Fatemeh Forouzesh, Eskandar Zand

bioRxiv 413237; doi: https://doi.org/10.1101/413237 New Results
DNMT inhibitors increase methylation of CpGs related to p53 pathway genes in colon, lymphoma, bladder, ovarian, and breast cancer cells
Anil K Giri, Tero Aittokallio

bioRxiv 395467; doi: https://doi.org/10.1101/395467 New Results

Pharmacology and Toxicology

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