Pharmacology and Toxicology

hb or not hb - when and why accounting for background mortality in toxicological survival models matters?
Julie Plantade, Virgile Baudrot, Sandrine Charles

bioRxiv 2023.01.25.525496; doi: https://doi.org/10.1101/2023.01.25.525496 New Results

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Evaluating the solubility of compounds intended for intramammary infusion based upon tests conducted across a range of milk products using cephapirin sodium and benzathine as model drugs
Marilyn N. Martinez, Fang Zhao, David G. Longstaff, Justin J. Gabriel, Martin J. Coffey

bioRxiv 2023.01.24.525429; doi: https://doi.org/10.1101/2023.01.24.525429 New Results

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The effects of repeated intraperitoneal administration of the GABA_B receptor agonist baclofen on body weight in rats maintained on a restricted feeding schedule
Ivor S. Ebenezer

bioRxiv 2023.01.24.525410; doi: https://doi.org/10.1101/2023.01.24.525410 New Results

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SynBa: Improved estimation of drug combination synergies with uncertainty quantification
Haoting Zhang, Carl Henrik Ek, Magnus Rattray, Marta Milo

bioRxiv 2023.01.24.524900; doi: https://doi.org/10.1101/2023.01.24.524900 New Results

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Competitive interaction between ATP and GTP regulates mitochondrial ATP-sensitive potassium channels
Plinio Bezerra Palácio, Geovanna Carvalho de Freitas Soares, Gabriella Moreira Bezerra Lima, Pedro Lourenzo Oliveira Cunha, Anna Lidia Nunes Varela, Heberty Tarso Facundo

bioRxiv 2023.01.24.525224; doi: https://doi.org/10.1101/2023.01.24.525224 New Results

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Lung infection by P. aeruginosa induces neuroinflammation and blood-brain barrier dysfunction in mice
Nuria Villalba, Yonggang Ma, Sarah A. Gahan, Aurelie Joly-Amado, Sam Spence, Xiaoyuan Yang, Kevin Nash, Sarah Y. Yuan

bioRxiv 2023.01.23.524949; doi: https://doi.org/10.1101/2023.01.23.524949 New Results

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A network pharmacology approach to assess the comparative pharmacodynamics of pharmaceutical excipient trehalose in human, mouse and rat
Jack Friend, Arun HS Kumar

bioRxiv 2023.01.23.525154; doi: https://doi.org/10.1101/2023.01.23.525154 New Results

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Data Driven Taxonomy for Antipsychotic Medication: A New Classification System
Robert A. McCutcheon, Paul J. Harrison, Oliver D. Howes, Philip K. McGuire, David Taylor, Toby Pillinger

bioRxiv 2023.01.23.524854; doi: https://doi.org/10.1101/2023.01.23.524854 New Results

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Performing Roux-N Y Gastric Bypass on Rabbits: Perspective Report to Evaluate Body Weight Changes Food Consumption, And the Malabsorption of Vitamin D3
Osaid Al Meanazel, Fars K. Alanazi, Mohammad Hailat, Wael Abu Dayyih, Ramadan Al-Shdefat, Mohammad Abu Assab, Riad Awad, Israa Al-Ani, Faiyaz Shakeel, Doaa H. Alshora, Mohamed A. Ibrahim

bioRxiv 2023.01.20.524848; doi: https://doi.org/10.1101/2023.01.20.524848 Confirmatory Results

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Quantitative proteomics combined with network pharmacology analysis unveils the biological basis of Schisandrin B in treating diabetic nephropathy
Jianying Song, Bo Zhang, Huiping Zhang, Wenbo Cheng, Peiyuan Liu, Jun Kang

bioRxiv 2023.01.19.524316; doi: https://doi.org/10.1101/2023.01.19.524316 New Results

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Pharmacology and Toxicology

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