Pharmacology and Toxicology

Comparison of antibiotic protein binding in human plasma vs. rabbit plasma
Maximilian Pesta, Markus Zeitlinger, Philip Datler, Georg Scheriau, Peter Wohlrab, Sabine Eberl, Edith Lackner, Claudia Franz, Walter Jaeger, Alexandra Maier-Salamon, Edda Tschernko

bioRxiv 2023.03.23.534048; doi: https://doi.org/10.1101/2023.03.23.534048 New Results

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Atmospheric transport of particulate matter and particulate-bound agrochemicals from beef cattle feedlots: human health implications for downwind agricultural communities
Amanda D Emert, Frank B Green, Kerry Griffis-Kyle, Philip N Smith

bioRxiv 2023.03.22.533817; doi: https://doi.org/10.1101/2023.03.22.533817 New Results

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Testosterone acts through membrane protein GPRC6A to cause cardiac edema in zebrafish embryos
Vahid Zadmajid, Daniel A. Gorelick

bioRxiv 2023.03.20.533512; doi: https://doi.org/10.1101/2023.03.20.533512 New Results

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Time-resolved cryo-EM of G protein activation by a GPCR
Makaía M. Papasergi-Scott, Guillermo Pérez-Hernández, Hossein Batebi, Yang Gao, Gözde Eskici, Alpay B. Seven, Ouliana Panova, Daniel Hilger, Marina Casiraghi, Feng He, Luis Maul, Peter Gmeiner, Brian K. Kobilka, Peter W. Hildebrand, Georgios Skiniotis

bioRxiv 2023.03.20.533387; doi: https://doi.org/10.1101/2023.03.20.533387 New Results

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Application of the ANDROMEDA Software for Prediction of the Human Pharmacokinetics of Modern Anticancer Drugs
Urban Fagerholm, Sven Hellberg, Jonathan Alvarsson, Ola Spjuth

bioRxiv 2023.03.18.533259; doi: https://doi.org/10.1101/2023.03.18.533259 New Results

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Compartment-Specific Activation of the Proton-Sensor GPR65 is Uncoupled from Receptor Trafficking
Loyda M. Morales Rodríguez, Stephanie E. Crilly, Jacob B. Rowe, Daniel G. Isom, Manojkumar A. Puthenveedu

bioRxiv 2023.03.18.533272; doi: https://doi.org/10.1101/2023.03.18.533272 New Results

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Does nonlinear blood-brain barrier transport matter for morphine dosing strategies?
Berfin Gülave, Divakar Budda, Mohammed AA Saleh, JG Coen van Hasselt, Elizabeth CM de Lange

bioRxiv 2023.03.17.533135; doi: https://doi.org/10.1101/2023.03.17.533135 New Results

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Finite Sample Adjustments for Average Equivalence Testing
Younes Boulaguiem, Julie Quartier, Maria Lapteva, Yogeshvar N. Kalia, Maria-Pia Victoria-Feser, Stéphane Guerrier, Dominique-Laurent Couturier

bioRxiv 2023.03.11.532179; doi: https://doi.org/10.1101/2023.03.11.532179 New Results

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COMT inhibitor tolcapone represses the migration and invasion of trophoblast and results in preeclampsia-like phenotypes in mice
Lu Chen, Menglan Pang, Qiuling Jie, Fei Sun, Liping Huang, Yanlin Ma, Xiaojing Yue

bioRxiv 2023.03.17.530517; doi: https://doi.org/10.1101/2023.03.17.530517 New Results

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Internalization-Responsive Nano-PLGA For Image-Guided Photodynamic Therapy Against HER2-Positive Breast Cancer
Anna S. Sogomonyan, Sergey M. Deyev, Victoria O. Shipunova

bioRxiv 2023.02.21.529435; doi: https://doi.org/10.1101/2023.02.21.529435 New Results

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Pharmacology and Toxicology

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