Pharmacology and Toxicology

Hydrophobicity drives the systemic distribution of lipid-conjugated siRNAs via lipid transport pathways
Maire F. Osborn, Andrew H Coles, Annabelle Biscans, Reka A Haraszti, Loic Roux, Sarah Davis, Socheata Ly, Dimas Echeverria, Matthew R. Hassler, Bruno M.D.C. Godinho, Mehran Nikan, Anastasia Khvorova

bioRxiv 288092; doi: https://doi.org/10.1101/288092 New Results
Molecular Modeling Suggests Homologous 2-APB Binding Sites in Connexins 26 and 32
Thomas W. Comollo

bioRxiv 287326; doi: https://doi.org/10.1101/287326 New Results
Behavioral and biochemical effects of ethanol withdrawal in zebrafish
Suianny N. S. Chaves, Gabriel R. Felicio, Bruna P. D. Costa, Witallo E. A. Oliveira, Monica G. Lima, Diogenes H. S. Silva, Caio Maximino

bioRxiv 201368; doi: https://doi.org/10.1101/201368 New Results
FGIN-1-27, an agonist at translocator protein 18 kDa (TSPO), produces anti-anxiety and anti-panic effects in non-mammalian models
Monica Gomes Lima, Jonathan Cueto-Escobedo, Juan Francisco Rodriguez-Landa, Caio Maximino

bioRxiv 056507; doi: https://doi.org/10.1101/056507 New Results
Putative rapid-acting antidepressant nitrous oxide ("laughing gas") evokes rebound emergence of slow EEG oscillations during which TrkB signaling is induced
Samuel Kohtala, Wiebke Theilmann, Marko Rosenholm, Paula Kiuru, Salla Uusitalo, Kaija Järventausta, Arvi Yli-Hankala, Jari Yli-Kauhaluoma, Henna-Kaisa Wigren, Tomi Rantamäki

bioRxiv 282954; doi: https://doi.org/10.1101/282954 New Results
Arsenite exposure inhibits histone acetyltransferase p300 for attenuating H3K27ac at enhancers in low-dose exposed mouse embryonic fibroblast cells
Yan Zhu, Yanqiang Li, Dan Lou, Yang Gao, JIng Yu, Dehui Kong, Qiang Zhang, Yankai Jia, Haimou Zhang, Zhibin Wang

bioRxiv 278424; doi: https://doi.org/10.1101/278424 New Results
Mid-Infrared Spectroscopy Study of Effects of Neonicotinoids on Forager Honey Bee (Apis mellifera) Fat Bodies and Their Connection to Colony Collapse Disorder
Yuzheng Feng, Aryan Luthra, Kaiwen Ding, Yang Yang, Jordan Savage, Xinrui Wei, Roland Moeschter, Sachin Ahuja, Victor Villegas, Bogdana Torbina, Anjuli Ahooja, Thomas Ellis, Anna-Maria Boechler, Andrew Roberts

bioRxiv 205112; doi: https://doi.org/10.1101/205112 New Results
Acute and chronic toxicity assessment of benzylpenicillin G residues in heat-treated animal food products
Cheng Cui, Xiang Zhang, Yang Wang, Shiying Lu, Huijun Lu, Qi Hui, Waqas Ahmad, Yan Cai, Xinlin Liu, Lingjiu Liu, Fengfeng Shi, Yanyan Liu, Ke Zhao, Feifei Zhai, Yangzhen Xiang, Pan Hu, Yansong Li, Honglin Ren, Ningyi Jin, Zengshan Liu

bioRxiv 191346; doi: https://doi.org/10.1101/191346 New Results
Antidepressant-like effect of losartan involves TRKB transactivation from angiotensin receptor type 2 (AGTR2) and recruitment of FYN
Cassiano Ricardo Alves Faria Diniz, Plinio Casarotto, Senem Merve Fred, Caroline Biojone, Eero Castren, Samia R. L. Joca

bioRxiv 168708; doi: https://doi.org/10.1101/168708 New Results
Effects Of Δ9-THC And Cannabidiol Vapor Inhalation In Male And Female Rats
Mehrak Javadi-Paydar, Jacques D Nguyen, Tony M Kerr, Yanabel Grant, Sophia A Vandewater, Maury Cole, Michael A Taffe

bioRxiv 128173; doi: https://doi.org/10.1101/128173 New Results

Pharmacology and Toxicology

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