Pharmacology and Toxicology

Unveiling the Impact of Arsenic Toxicity on Immune Cells in Atherosclerotic Plaques: Insights from Single-Cell Multi-Omics Profiling
Kiran Makhani, Xiuhui Yang, France Dierick, Nivetha Subramaniam, Natascha Gagnon, Talin Ebrahimian, Hao Wu, Jun Ding, Koren K. Mann

bioRxiv 2023.11.23.568429; doi: https://doi.org/10.1101/2023.11.23.568429 New Results

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Towards new AQP4 inhibitors: ORI-TRN-002
Michael Thormann, Nadine Traube, Nasser Yehia, Roland Koestler, Gergana Galabova, Nanna MacAulay, Trine L. Toft-Bertelsen

bioRxiv 2023.11.22.568252; doi: https://doi.org/10.1101/2023.11.22.568252 New Results

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Single-molecule tracking-based drug screening
Daisuke Watanabe, Michio Hiroshima, Masahiro Ueda

bioRxiv 2023.11.12.566743; doi: https://doi.org/10.1101/2023.11.12.566743 New Results

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Enhancing Drug Delivery with Supramolecular Amphiphilic Macrocycle Nanoparticles: Selective Targeting of CDK4/6 Inhibitor Palbociclib to Melanoma
Mohamed F. Attia, Edikan A. Ogunnaike, Megan Pitz, Nancy M. Elbaz, Dillip K. Panda, Angela Alexander-Bryant, Sourav Saha, Daniel C. Whitehead, Alexander Kabanov

bioRxiv 2023.11.21.567974; doi: https://doi.org/10.1101/2023.11.21.567974 New Results

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The effect of ciprofloxacin and gentamicin on wound healing in ex vivo sheep cornea model
K. Okurowska, D. R. Manrique Suarez, E. Karunakaran

bioRxiv 2023.11.20.567943; doi: https://doi.org/10.1101/2023.11.20.567943 New Results

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Dysregulated Platelet Function in Patients with Post-Acute Sequelae of COVID-19
Anu Aggarwal, Tamanna K. Singh, Michael Pham, Matthew Godwin, Rui Chen, Thomas M. McIntyre, Alliefair Scalise, Mina K. Chung, Courtney Jennings, Mariya Ali, Hiijun Park, Kristin Englund, Alok A. Khorana, Lars G. Svensson, Samir Kapadia, Keith R. McCrae, Scott J. Cameron

bioRxiv 2023.06.18.545507; doi: https://doi.org/10.1101/2023.06.18.545507 New Results

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ANDROMEDA by Prosilico Software Successfully Predicts Human Clinical Pharmacokinetics of 300 Drugs Out of Reach for In Vitro Methods
Urban Fagerholm, Sven Hellberg, Jonathan Alvarsson, Ola Spjuth

bioRxiv 2022.10.05.511015; doi: https://doi.org/10.1101/2022.10.05.511015 New Results

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The nematode (Ascaris suum) intestine is a location of synergistic anthelmintic effects of Cry5B and levamisole
Paul D. E. Williams, Matthew T. Brewer, Raffi Aroian, Alan P. Robertson, Richard J. Martin

bioRxiv 2023.11.20.567786; doi: https://doi.org/10.1101/2023.11.20.567786 New Results

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An organic extract from ascidian Ciona robusta induces cytotoxic autophagy in human malignant cell lines
Alessandra Gallo, Ylenia Maria Penna, Maria Russo, Marco Rosapane, Elisabetta Tosti, Gian Luigi Russo

bioRxiv 2023.11.18.567676; doi: https://doi.org/10.1101/2023.11.18.567676 Confirmatory Results

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The thiol methyltransferase activity of TMT1A (METTL7A) is conserved across species
José M. González Dalmasy, Christina M. Fitzsimmons, William J.E. Frye, Andrew J. Perciaccante, Connor P. Jewell, Lisa M. Jenkins, Pedro J. Batista, Robert W. Robey, Michael M. Gottesman

bioRxiv 2023.11.17.567538; doi: https://doi.org/10.1101/2023.11.17.567538 New Results

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Pharmacology and Toxicology

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