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Pharmacology and Toxicology

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  • Unveiling the Impact of Arsenic Toxicity on Immune Cells in Atherosclerotic Plaques: Insights from Single-Cell Multi-Omics Profiling
    Kiran Makhani, Xiuhui Yang, France Dierick, Nivetha Subramaniam, Natascha Gagnon, Talin Ebrahimian, Hao Wu, Jun Ding, Koren K. Mann
    bioRxiv 2023.11.23.568429; doi: https://doi.org/10.1101/2023.11.23.568429 New Results
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  • Towards new AQP4 inhibitors: ORI-TRN-002
    Michael Thormann, Nadine Traube, Nasser Yehia, Roland Koestler, Gergana Galabova, Nanna MacAulay, Trine L. Toft-Bertelsen
    bioRxiv 2023.11.22.568252; doi: https://doi.org/10.1101/2023.11.22.568252 New Results
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  • Single-molecule tracking-based drug screening
    Daisuke Watanabe, Michio Hiroshima, Masahiro Ueda
    bioRxiv 2023.11.12.566743; doi: https://doi.org/10.1101/2023.11.12.566743 New Results
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  • Enhancing Drug Delivery with Supramolecular Amphiphilic Macrocycle Nanoparticles: Selective Targeting of CDK4/6 Inhibitor Palbociclib to Melanoma
    Mohamed F. Attia, Edikan A. Ogunnaike, Megan Pitz, Nancy M. Elbaz, Dillip K. Panda, Angela Alexander-Bryant, Sourav Saha, Daniel C. Whitehead, Alexander Kabanov
    bioRxiv 2023.11.21.567974; doi: https://doi.org/10.1101/2023.11.21.567974 New Results
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  • The effect of ciprofloxacin and gentamicin on wound healing in ex vivo sheep cornea model
    K. Okurowska, D. R. Manrique Suarez, E. Karunakaran
    bioRxiv 2023.11.20.567943; doi: https://doi.org/10.1101/2023.11.20.567943 New Results
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  • Dysregulated Platelet Function in Patients with Post-Acute Sequelae of COVID-19
    Anu Aggarwal, Tamanna K. Singh, Michael Pham, Matthew Godwin, Rui Chen, Thomas M. McIntyre, Alliefair Scalise, Mina K. Chung, Courtney Jennings, Mariya Ali, Hiijun Park, Kristin Englund, Alok A. Khorana, Lars G. Svensson, Samir Kapadia, Keith R. McCrae, Scott J. Cameron
    bioRxiv 2023.06.18.545507; doi: https://doi.org/10.1101/2023.06.18.545507 New Results
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  • ANDROMEDA by Prosilico Software Successfully Predicts Human Clinical Pharmacokinetics of 300 Drugs Out of Reach for In Vitro Methods
    Urban Fagerholm, Sven Hellberg, Jonathan Alvarsson, Ola Spjuth
    bioRxiv 2022.10.05.511015; doi: https://doi.org/10.1101/2022.10.05.511015 New Results
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  • The nematode (Ascaris suum) intestine is a location of synergistic anthelmintic effects of Cry5B and levamisole
    Paul D. E. Williams, Matthew T. Brewer, Raffi Aroian, Alan P. Robertson, Richard J. Martin
    bioRxiv 2023.11.20.567786; doi: https://doi.org/10.1101/2023.11.20.567786 New Results
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  • An organic extract from ascidian Ciona robusta induces cytotoxic autophagy in human malignant cell lines
    Alessandra Gallo, Ylenia Maria Penna, Maria Russo, Marco Rosapane, Elisabetta Tosti, Gian Luigi Russo
    bioRxiv 2023.11.18.567676; doi: https://doi.org/10.1101/2023.11.18.567676 Confirmatory Results
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  • The thiol methyltransferase activity of TMT1A (METTL7A) is conserved across species
    José M. González Dalmasy, Christina M. Fitzsimmons, William J.E. Frye, Andrew J. Perciaccante, Connor P. Jewell, Lisa M. Jenkins, Pedro J. Batista, Robert W. Robey, Michael M. Gottesman
    bioRxiv 2023.11.17.567538; doi: https://doi.org/10.1101/2023.11.17.567538 New Results
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