Pharmacology and Toxicology

Unexpected Loss of Sensitivity to the nAChR Antagonist Activity of Mecamylamine and DHβE in Nicotine-Tolerant C57BL/6J Mice
Lance McMahon, Fernando de Moura

bioRxiv 482075; doi: https://doi.org/10.1101/482075 New Results
Cannabichromene is a cannabinoid CB2 receptor agonist
Michael Philip Udoh, Marina J Santiago, Steven Devenish, Iain S McGregor, Mark Connor

bioRxiv 435057; doi: https://doi.org/10.1101/435057 New Results
Garcinia cambogia extract removes calcium oxalate kidney stones in both genetic and non-genetic Drosophila models of nephrolithiasis
Qiuxia Fan, Xiaoming Feng, Xizhen Hong, Siqiao Gong, Jianwei Tian, Fanfan Hou, Fujian Zhang

bioRxiv 477570; doi: https://doi.org/10.1101/477570 New Results
Synthesis, SAR and Docking Studies of Substituted Aryl phenylthiazolyl phenylcarboxamide as potential Protein Tyrosine Phosphatase 1B Inhibitors
Kanika Varshney, Amit K Gupta, Arun Rawat, Rohit Srivastava, Akansha Mishra, Mridula Saxena, Arvind K. Srivastava, Sudha Jain, Anil K Saxena

bioRxiv 472670; doi: https://doi.org/10.1101/472670 New Results
Design of a GAK/EGFR inhibitor set to interrogate the relationship of EGFR and GAK in chordoma
Christopher Asquith, Kaleb Naegeli, Michael P. East, Tuomo Laitinen, Tammy M. Havener, Carrow I. Wells, Gary L. Johnson, David H. Drewry, William J Zuercher, David C. Morris

bioRxiv 475251; doi: https://doi.org/10.1101/475251 New Results
Soil nutrient adequacy for optimal cassava growth, implications on cyanogenic glucoside production: a case of konzo-affected Mtwara region, Tanzania
Matema L.E. Imakumbili, Ernest Semu, Johnson M.R. Semoka, Adebayo Abass, Geoffrey Mkamilo

bioRxiv 464594; doi: https://doi.org/10.1101/464594 New Results
Evaluating Improvements to Exposure Estimates from Fate and Transport Models by Incorporating Environmental Sampling Effort and Landscape-level Contaminant Use
Samantha L Rumschlag, Jason R Rohr, Scott Bessler

bioRxiv 472969; doi: https://doi.org/10.1101/472969 New Results
Effects Of High Copper Exposure On Development And Survival During Early Ontogenesis In The Common Toad
Elena V Dmitrieva

bioRxiv 471466; doi: https://doi.org/10.1101/471466 New Results
Utilizing comprehensive and mini-kinome panels to optimize the selectivity of quinoline inhibitors for cyclin G associated kinase (GAK)
Christopher Asquith, Caleb Hopkins, Daniel K. Treiber, William Zuercher

bioRxiv 471615; doi: https://doi.org/10.1101/471615 New Results
Low-dose cadmium potentiates lung inflammatory response to 2009 pandemic H1N1 influenza virus in mice
Joshua D. Chandler, Xin Hu, Eunju Ko, Soojin Park, Jolyn Fernandes, Young-Tae Lee, Michael L. Orr, Li Hao, Matthew Ryan Smith, David C. Neujahr, Karan Uppal, Sang-Moo Kang, Dean P. Jones, Young-Mi Go

bioRxiv 346866; doi: https://doi.org/10.1101/346866 New Results

Pharmacology and Toxicology

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