Pharmacology and Toxicology

Predicting negative control drugs to support research in drug safety
Yun Hao, Nicholas P. Tatonetti

bioRxiv 380832; doi: https://doi.org/10.1101/380832 New Results
Drug adaptation influences cardiotoxicity caused by tyrosine kinase inhibitors in iPSC-derived human cardiomyocytes
Huan Wang, Robert P Sheehan, Adam C Palmer, Robert A Everley, Sarah A Boswell, Noga Ron-Harel, Kristina M Holton, Connor A Jacobson, Alison Erickson, Laura Maliszewski, Marcia C Haigis, Peter K Sorger

bioRxiv 365841; doi: https://doi.org/10.1101/365841 New Results
Development and Application of a High-Content Virion Display Human GPCR Array
Guan-Da Syu, Shih-Chin Wang, Guangzhong Ma, Shuang Liu, Donna Pearce, Atish Prakash, Brandon Henson, Lien-Chun Weng, Devlina Ghosh, Pedro Ramos, Daniel Eichinger, Ignacio Pino, Xinzhong Dong, Jie Xiao, Shaopeng Wang, Nongjian Tao, Kwang Sik Kim, Prashant J. Desai, Heng Zhu

bioRxiv 377754; doi: https://doi.org/10.1101/377754 New Results
Atropselective Oxidation of 2,2',3,3',4,6'-Hexachlorobiphenyl (PCB 132) to Hydroxylated Metabolites by Human Liver Microsomes: Involvement of Arene Oxide Intermediates
Eric Uwimana, Xueshu Li, Coby Yeung, Eric V. Patterson, Hans-Joachim Lehmler

bioRxiv 373837; doi: https://doi.org/10.1101/373837 New Results
Sapropterin Treatment Prevents Congenital Heart Defects Induced by Pregestational Diabetes in Mice
Anish Engineer, Tana Saiyin, Xiangru Lu, Andrew S. Kucey, Brad L. Urquhart, Thomas A. Drysdale, Kambiz Norozi, Qingping Feng

bioRxiv 304006; doi: https://doi.org/10.1101/304006 New Results
Development of an imaging toolbox to assess the therapeutic potential and biodistribution of macrophages in a mouse model of multiple organ dysfunction
Jack Sharkey, Lorenzo Ressel, Nathalie Brillant, Bettina Wilm, Kevin Park, Patricia Murray

bioRxiv 372482; doi: https://doi.org/10.1101/372482 New Results
Apigenin relaxes rat intrarenal arteries: involvement of Cl- channels and K+ channels
Yixin Jing, Miaomiao Dong, Yu Liu, Xiaomin Hou, Pengmei Guo, Weiping Li, Mingsheng Zhang, Jiyuan Lv

bioRxiv 371849; doi: https://doi.org/10.1101/371849 New Results
Costing 'the' MTD ... in 2-D
David C Norris

bioRxiv 370817; doi: https://doi.org/10.1101/370817 New Results
Moderate developmental alcohol exposure reduces repetitive alternation in a zebrafish model of fetal alcohol spectrum disorders.
Madeleine Cleal, Matthew O Parker

bioRxiv 370072; doi: https://doi.org/10.1101/370072 New Results
Anticlastogenic Effect of Ulva Fasciata, Against Cyclophosphamide and Mitomycin C Induced Chromosomal Damage in Swiss Albino Mice
Jayashree Dolpady, Vijayalaxmi KK

bioRxiv 370031; doi: https://doi.org/10.1101/370031 New Results

Pharmacology and Toxicology

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