Pharmacology and Toxicology

Assessment of NR4A Ligands that Directly Bind and Modulate the Orphan Nuclear Receptor Nurr1
Paola Munoz-Tello, Hua Lin, Pasha Khan, Ian Mitchelle S. de Vera, Theodore M. Kamenecka, Douglas J. Kojetin

bioRxiv 2020.05.22.109017; doi: https://doi.org/10.1101/2020.05.22.109017 New Results

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Repurposing beta3-adrenergic receptor agonists for Alzheimer’s disease: Beneficial effects on recognition memory and amyloid pathology in a mouse model
Marine Tournissac, Tra-My Vu, Nika Vrabic, Clara Hozer, Cyntia Tremblay, Koralie Mélançon, Emmanuel Planel, Fabien Pifferi, Frédéric Calon

bioRxiv 2020.05.25.114454; doi: https://doi.org/10.1101/2020.05.25.114454 New Results

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Longitudinal assessment of mycotoxin co-exposures in exclusively breastfed infants
Dominik Braun, Eva Schernhammer, Doris Marko, Benedikt Warth

bioRxiv 2020.03.27.011072; doi: https://doi.org/10.1101/2020.03.27.011072 New Results

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Validation of an LC-MS/MS Assay for the Simultaneous Determination of Bictegravir, Doravirine, and Raltegravir in Human Plasma
Amanda P. Schauer, Craig Sykes, Mackenzie L Cottrell, Angela DM Kashuba

bioRxiv 2020.05.21.104125; doi: https://doi.org/10.1101/2020.05.21.104125 New Results

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Targeting the SARS-CoV-2 Main Protease to Repurpose Drugs for COVID-19
Erol C. Vatansever, Kai Yang, Kaci C. Kratch, Aleksandra Drelich, Chia-Chuan Cho, Drake M. Mellot, Shiqing Xu, Chien-Te K. Tseng, Wenshe Ray Liu

bioRxiv 2020.05.23.112235; doi: https://doi.org/10.1101/2020.05.23.112235 New Results

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Pathophysiological regulation of lung function by the free fatty acid receptor FFA4
Rudi Prihandoko, Davinder Kaur, Coen H. Wiegman, Elisa Alvarez-Curto, Chantal Donovan, Latifa Chachi, Trond Ulven, Martha R. Tyas, Eloise Euston, Zhaoyang Dong, Abdulrahman Ghali M Alharbi, Richard Kim, Jack G. Lowe, Philip M. Hansbro, Kian Fan Chung, Christopher E. Brightling, Graeme Milligan, Andrew B. Tobin

bioRxiv 2020.05.18.101170; doi: https://doi.org/10.1101/2020.05.18.101170 New Results

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Effects of genetic variability of CYP2D6 on neural substrates of sustained attention during on-task activity
Roberto Viviani, Irene Messina, Julia E. Bosch, Lisa Dommes, Anna Paul, Katharina L. Schneider, Catharina Scholl, Julia C. Stingl

bioRxiv 831198; doi: https://doi.org/10.1101/831198 New Results

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In silico molecular target prediction unveils mebendazole as a potent MAPK14 inhibitor
Jeremy Ariey-Bonnet, Kendall Carrasco, Marion Le Grand, Laurent Hoffer, Stéphane Betzi, Mickael Feracci, Philipp Tsvetkov, Francois Devred, Yves Collette, Xavier Morelli, Pedro Ballester, Eddy Pasquier

bioRxiv 2020.05.18.101329; doi: https://doi.org/10.1101/2020.05.18.101329 New Results

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Glycosaminoglycans are specific endosomal receptors for Yersinia pseudotuberculosis Cytotoxic Necrotizing Factor
Stefanie Kowarschik, Julian Schöllkopf, Thomas Müller, Songhai Tian, Julian Knerr, Hans Bakker, Stephan Rein, Min Dong, Stefan Weber, Robert Grosse, Gudula Schmidt

bioRxiv 2020.05.18.101790; doi: https://doi.org/10.1101/2020.05.18.101790 New Results

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A therapeutic combination of two small molecule toxin inhibitors provides pancontinental preclinical efficacy against viper snakebite
Laura-Oana Albulescu, Chunfang Xie, Stuart Ainsworth, Jaffer Alsolaiss, Edouard Crittenden, Charlotte A. Dawson, Rowan Softley, Keirah E. Bartlett, Robert A. Harrison, Jeroen Kool, Nicholas R. Casewell

bioRxiv 2020.05.13.094599; doi: https://doi.org/10.1101/2020.05.13.094599 New Results

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Pharmacology and Toxicology

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