Pharmacology and Toxicology

Transdermal patch containing physostigmine and procyclidine protects rhesus monkeys against VX intoxication
Young Jo Song

bioRxiv 2020.10.16.343434; doi: https://doi.org/10.1101/2020.10.16.343434 New Results

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Chemical Systems Biology Reveals Mechanisms of Glucocorticoid Receptor Signaling
Nelson E. Bruno, Jerome C. Nwachukwu, Sathish Srinivasan, Charles C. Nettles, Tina Izard, Zhuang Jin, Siddaraju V. Boregowda, Donald G. Phinney, Olivier Elemento, Xu Liu, Eric A. Ortlund, René Houtman, Diana A. Stavreva, Gordon L. Hager, Theodore M. Kamenecka, Douglas J. Kojetin, Kendall W. Nettles

bioRxiv 2020.06.15.153270; doi: https://doi.org/10.1101/2020.06.15.153270 New Results

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Chronic exposure of ErbB TKIs inhibits DRA expression and activity through an ERK/Elk-1/CREB/AP-1 dependent pathway
Hong Yang, Ru-Xian Lin, Rafiquel Sarker, Mark Donowitz

bioRxiv 2020.10.16.342139; doi: https://doi.org/10.1101/2020.10.16.342139 New Results

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Comparison of morphine, oxycodone and the biased MOR agonist SR-17018 for tolerance and efficacy in mouse models of pain
Fani Pantouli, Travis W. Grim, Cullen L. Schmid, Agnes Acevedo-Canabal, Nicole M. Kennedy, Thomas D. Bannister, Laura M. Bohn

bioRxiv 2020.10.16.341776; doi: https://doi.org/10.1101/2020.10.16.341776 New Results

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Drug synergy of combinatory treatment with remdesivir and the repurposed drugs fluoxetine and itraconazole effectively impairs SARS-CoV-2 infection in vitro
Sebastian Schloer, Linda Brunotte, Angeles Mecate-Zambrano, Shuyu Zheng, Jing Tang, Stephan Ludwig, Ursula Rescher

bioRxiv 2020.10.16.342410; doi: https://doi.org/10.1101/2020.10.16.342410 New Results

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Metalloprotease Gp63 targeting novel glycoside exhibits potential antileishmanial activity
Amrita Chakrabarti, Chintam Narayana, Nishant Joshi, Swati Garg, Lalit Garg, Ram Sagar, Soumya Pati, Shailja Singh

bioRxiv 2020.09.11.292920; doi: https://doi.org/10.1101/2020.09.11.292920 New Results

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Bixafen, a succinate dehydrogenase inhibitor fungicide, causes microcephaly and motor neuron axon defects during development
Alexandre Brenet, Rahma Hassan-Abdi, Nadia Soussi-Yanicostas

bioRxiv 2020.08.15.252254; doi: https://doi.org/10.1101/2020.08.15.252254 New Results

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Female rats self-administer heroin by vapor inhalation
Arnold Gutierrez, Jacques D. Nguyen, Kevin M. Creehan, Michael A. Taffe

bioRxiv 2020.03.30.016725; doi: https://doi.org/10.1101/2020.03.30.016725 New Results

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Diazepam attenuates the effects of cocaine on locomotion, 50-kHz ultrasonic vocalizations and phasic dopamine release in the nucleus accumbens of rats
William N. Sanchez, Jose A. Pochapski, Leticia F. Jessen, Marek Ellenberger, Rainer K. Schwarting, Donita L. Robinson, Roberto Andreatini, Claudio Da Cunha

bioRxiv 2020.10.13.338343; doi: https://doi.org/10.1101/2020.10.13.338343 New Results

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Characterization, and Anti-microbial Properties of Zinc Oxide Nanoparticles Synthesized Using Citrus sinensis (L.) Osbeck Peel Extract
Dharma Prasad Khanal, Sadikshya Aryal, Samyam Aryal

bioRxiv 2020.10.13.337022; doi: https://doi.org/10.1101/2020.10.13.337022 Confirmatory Results

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Pharmacology and Toxicology

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