Pharmacology and Toxicology

Dugesia japonica is the best suited of three planarian species for high-throughput toxicology screening
Danielle Ireland, Veronica Bochenek, Daniel Chaiken, Christina Rabeler, Sumi Onoe, Ameet Soni, Eva-Maria S. Collins

bioRxiv 2020.01.23.917047; doi: https://doi.org/10.1101/2020.01.23.917047 New Results

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Effect of Perfluorooctanesulfonic acid (PFOS) on immune cell development and function in mice
Luisa Torres, Amie Redko, Brian Imbiakha, Candice Limper, Sue Chang, Avery August

bioRxiv 2020.01.20.913293; doi: https://doi.org/10.1101/2020.01.20.913293 New Results

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In vivo characterisation of the toxicological properties of DPhP, one of the main degradation products of aryl phosphate esters
Samia Ruby, Jesús Marín-Sáez, Aurélie Fildier, Audrey Buleté, Myriam Abdallah, Jessica Garcia, Julie Deverchère, Loïc Spinner, Barbara Giroud, Sébastien Ibanez, Thierry Granjon, Claire Bardel, Alain Puisieux, Béatrice Fervers, Emmanuelle Vulliet, Léa Payen, Arnaud M. Vigneron

bioRxiv 2019.12.26.888057; doi: https://doi.org/10.1101/2019.12.26.888057 New Results

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Antigens in water-in-oil emulsion: a simple antigen extraction method for analysis and proof of equal antigen distribution in vaccination syringe after mixture
Michael Ghosh, Marion Gauger, Monika Denk, Hans-Georg Rammensee, Stefan Stevanović

bioRxiv 2020.01.22.916189; doi: https://doi.org/10.1101/2020.01.22.916189 New Results

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Schistosomes alter expression of immunomodulatory gene products following in vivo praziquantel exposure
Paul McCusker, Claudia M. Rohr, John D. Chan

bioRxiv 2020.01.22.915710; doi: https://doi.org/10.1101/2020.01.22.915710 New Results

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Exploiting toxin internalization receptors to enhance delivery of proteins to lysosomes for enzyme replacement therapy
Seiji N. Sugiman-Marangos, Greg L. Beilhartz, Xiaochu Zhao, Dongxia Zhou, Rong Hua, Peter K. Kim, James M. Rini, Berge A. Minassian, Roman A. Melnyk

bioRxiv 2020.01.22.915298; doi: https://doi.org/10.1101/2020.01.22.915298 New Results

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Hesperetin inhibits foam cell formation in macrophages via activating LXRα signal in an AMPK dependent manner
Xuanjing Chen, Dezhi Zou, Xiaoling Chen, Huanlin Wu, Danping Xu

bioRxiv 2020.01.22.915819; doi: https://doi.org/10.1101/2020.01.22.915819 New Results

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Toxic effect of 2,2’-bis(bicyclo[2.2.1] heptane) on bacterial cells
A. G. Kessenikh, E. Yu. Gnuchikh, S. V. Bazhenov, M. V. Bermeshev, V. G. Pevgov, V. O. Samoilov, S. V. Shorunov, A. L. Maksimov, L. S. Yaguzhinsky, I. V. Manukhov

bioRxiv 2020.01.21.913699; doi: https://doi.org/10.1101/2020.01.21.913699 New Results

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Functional anatomy of the full length CXCR4-CXCL12 complex systematically dissected by quantitative model-guided mutagenesis
Bryan S. Stephens, Tony Ngo, Irina Kufareva, Tracy M. Handel

bioRxiv 2020.01.21.913772; doi: https://doi.org/10.1101/2020.01.21.913772 New Results

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Schisandrin B for treatment of male infertility
Di-Xin Zou, Xue-Dan Meng, Ying Xie, Rui Liu, Jia-Lun Duan, Chun-Jie Bao, Yi-Xuan Liu, Ya-Fei Du, Jia-Rui Xu, Qian Luo, Zhan Zhang, Shuang Ma, Wei-Peng Yang, Rui-Chao Lin, Wan-Liang Lu

bioRxiv 2020.01.20.912147; doi: https://doi.org/10.1101/2020.01.20.912147 New Results

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Pharmacology and Toxicology

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