Pharmacology and Toxicology

Bupropion inhibits serotonin type 3AB heteromeric channels at a physiologically relevant concentration
Antonia G. Stuebler, Michaela Jansen

bioRxiv 709881; doi: https://doi.org/10.1101/709881 New Results

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A NanoBRET-based binding assay for Smoothened allows real time analysis of small-molecule ligand binding and distinction of two separate ligand binding sites for BODIPY-cyclopamine
Paweł Kozielewicz, Carl-Fredrik Bowin, Gunnar Schulte

bioRxiv 706028; doi: https://doi.org/10.1101/706028 New Results

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Nutritive diet becomes unhealthy if taken in a wrong ratio: Scientific validation of Ayurvedic concept of “incompatible diet” (Virrudh Aahar)
Prerana Aditi, Shivani Srivastva, Harsh pandey, Y.B. Tripathi

bioRxiv 708859; doi: https://doi.org/10.1101/708859 New Results

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Pharmacological Characterisation of Novel Adenosine Receptor A₃R Antagonists
Kerry Barkan, Panagiotis Lagarias, Eleni Vrontaki, Dimitrios Stamatis, Sam Hoare, Karl-Norbert Klotz, Antonios Kolocouris, Graham Ladds

bioRxiv 693796; doi: https://doi.org/10.1101/693796 New Results

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Vapor inhalation of cannabidiol (CBD) in rats
Mehrak Javadi-Paydar, Kevin M. Creehan, Tony M. Kerr, Michael A. Taffe

bioRxiv 659250; doi: https://doi.org/10.1101/659250 New Results

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In silico screening of GMQ-like compounds reveals guanabenz and sephin1 as new allosteric modulators of acid-sensing ion channel 3
Gerard Callejo, Luke A. Pattison, Jack C. Greenhalgh, Sampurna Chakrabarti, Evangelia Andreopoulou, James R. F. Hockley, Ewan St. John Smith, Taufiq Rahman

bioRxiv 704445; doi: https://doi.org/10.1101/704445 New Results

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Virtual screening identifies novel high-affinity σ₁ receptor ligands
Daniel A. Greenfield, Hayden R. Schmidt, Piotr Sliz, Andrew C. Kruse

bioRxiv 699793; doi: https://doi.org/10.1101/699793 New Results

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Analysis of the Mutant Selection Window and Killing of Mycoplasma hyopneumoniae for Doxycycline, Tylosin, Danofloxacin, Tiamulin, and Valnemulin
Zilong Huang, Chunxiao Mao, Yanzhe Wei, Xiaoyan Gu, Qinren Cai, Xiangguang Shen, Huanzhong Ding

bioRxiv 704650; doi: https://doi.org/10.1101/704650

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Discovering therapeutic activities from venoms using differential gene expression
Joseph D. Romano, Hai Li, Ronald Realubit, Charles Karan, Nicholas P. Tatonetti

bioRxiv 699280; doi: https://doi.org/10.1101/699280

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An updated analysis of opioids increasing the risk of fractures
Qiaoning Yue, Yue Ma, Yirong Teng, Yun Zhu, Hao Liu, Shuanglan Xu, Jie Liu, Jianping Liu, Zhaowei Teng, Xiguang Zhang

bioRxiv 701094; doi: https://doi.org/10.1101/701094 Confirmatory Results

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Pharmacology and Toxicology

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