Pharmacology and Toxicology

Discovery of highly potent pancoronavirus fusion inhibitors that also effectively inhibit COVID-19 variants from the UK (Alpha), South Africa (Beta), and India (Delta)
Francesca Curreli, Shahad Ahmed, Sofia M. B. Victor, Aleksandra Drelich, Siva S. Panda, Andrea Altieri, Alexander V. Kurkin, Chien-Te K. Tseng, Christopher D. Hillyer, Asim K. Debnath

bioRxiv 2021.09.03.458877; doi: https://doi.org/10.1101/2021.09.03.458877 New Results

Add to Selected Citations
Development of a machine learning model to estimate biotic ligand model-based predicted no□effect concentrations for copper in freshwater
Jiwoong Chung, Geonwoo Yoo, Jinhee Choi, Jong-Hyeon Lee

bioRxiv 2021.09.16.460690; doi: https://doi.org/10.1101/2021.09.16.460690 New Results

Add to Selected Citations
Inhibition of sodium conductance by cannabigerol contributes to a reduction of neuronal dorsal root ganglion excitability
Mohammad-Reza Ghovanloo, Mark Estacion, Peng Zhao, Sulayman Dib-Hajj, Stephen G. Waxman

bioRxiv 2021.09.14.460359; doi: https://doi.org/10.1101/2021.09.14.460359 New Results

Add to Selected Citations
A G-protein-biased S1P₁ agonist, SAR247799, improved LVH and diastolic function in a rat model of metabolic syndrome
Maria-Francesca Evaristi, Bruno Poirier, Xavier Chénedé, Anne-Marie Lefebvre, Alain Roccon, Florence Gillot, Sandra Beeské, Alain Corbier, Marie-Pierre Pruniaux-Harnist, Philip Janiak, Ashfaq A. Parkar

bioRxiv 2021.09.14.460397; doi: https://doi.org/10.1101/2021.09.14.460397 New Results

Add to Selected Citations
Longitudinal effects of using and discontinuing CNS medications on cognitive functioning
Elise Koch, Kristina Johnell, Karolina Kauppi

bioRxiv 2021.09.13.460082; doi: https://doi.org/10.1101/2021.09.13.460082 New Results

Add to Selected Citations
Investigation of a derived adverse outcome pathway (AOP) network for endocrine-mediated perturbations
Janani Ravichandran, Bagavathy Shanmugam Karthikeyan, Areejit Samal

bioRxiv 2021.09.14.460266; doi: https://doi.org/10.1101/2021.09.14.460266 New Results

Add to Selected Citations
Model-Based Meta-Analysis of Relapsing Mouse Model Studies from the Critical Path to Tuberculosis Drug Regimens Initiative Database
Alexander Berg, James Clary, Debra Hanna, Eric Nuermberger, Anne Lenaerts, Nicole Ammerman, Michelle Ramey, Dan Hartley, David Hermann

bioRxiv 2021.09.13.460195; doi: https://doi.org/10.1101/2021.09.13.460195 New Results

Add to Selected Citations
Extracellular vesicles mediate the intercellular exchange of nanoparticles
Xian Wu, Tang Tang, Yushuang Wei, Katherine A. Cummins, David K. Wood, Hong-Bo Pang

bioRxiv 2021.02.23.432325; doi: https://doi.org/10.1101/2021.02.23.432325 New Results

Add to Selected Citations
Peroxide antimalarial drugs target redox homeostasis in Plasmodium falciparum infected red blood cells
Ghizal Siddiqui, Carlo Giannangelo, Amanda De Paoli, Anna Katharina Schuh, Kim C. Heimsch, Dovile Anderson, Timothy G. Brown, Christopher A. MacRaild, Jianbo Wu, Xiaofang Wang, Yuxiang Dong, Jonathan L. Vennerstrom, Katja Becker, Darren J Creek

bioRxiv 2021.09.10.459878; doi: https://doi.org/10.1101/2021.09.10.459878 New Results

Add to Selected Citations
Applying Historical Data in a Nonlinear Mixed-Effects Model Can Reduce the Number of Control Rats Required for Calculation of The Relative Potency of Insulin Analogues
Emilie Prang Nielsen, Søren Andersen, Christian Lehn Brand, Susanne Ditlevsen

bioRxiv 2021.09.10.459831; doi: https://doi.org/10.1101/2021.09.10.459831 New Results

Add to Selected Citations

Pharmacology and Toxicology

Pages