Pharmacology and Toxicology

Comparative analysis of molecular signatures suggests the use of gabapentin for the management of endometriosis-associated pain
Brice Bellessort, Anne Bachelot, Virginie Grouthier, Camille De Lombares, Nicolas Narboux-Nême, Paolo Garagnani, Chiara Pirazzini, Simonetta Astigiano, Luca Mastracci, Anastasia Fontaine, Gladys Alfama, Evelyne Duvernois-Berthet, Giovanni Levi

bioRxiv 251397; doi: https://doi.org/10.1101/251397 New Results
Improving the Generation and Selection of Virtual Populations in Quantitative Systems Pharmacology Models
Theodore R. Rieger, Richard J. Allen, Lukas Bystricky, Yuzhou Chen, Glen Colopy, Yifan Cui, Angelica Gonzalez, Yifei Liu, Rebekah White, Rebecca Everett, H. T. Banks, Cynthia J. Musante

bioRxiv 196089; doi: https://doi.org/10.1101/196089 New Results
Navigating in vitro bioactivity data: investigating available resources using model compounds
Sten Ilmjarv, Fiona Augsburger, Jerven Tjalling Bolleman, Robin Liechti, Alan Bridge, Jenny Sandstrom, Vincent Jaquet, Ioannis Xenarios, Karl-Heinz Krause

bioRxiv 248898; doi: https://doi.org/10.1101/248898 New Results
Precautionary Coherence Unravels Dose Escalation Designs
David C. Norris

bioRxiv 240846; doi: https://doi.org/10.1101/240846 New Results
Broad spectrum proteomics analysis of the inferior Colliculus following acute hydrogen sulfide exposure
Dong-Suk Kim, Poojya Anantharam, Andrea Hoffman, Mitchell L Meade, Nadja Grobe, Jeffery M Gearhart, Elizabeth M Whitley, Belinda Mahama, Wilson K Rumbeiha

bioRxiv 237370; doi: https://doi.org/10.1101/237370 New Results
Silver microwires from treating tooth decay with silver diamine fluoride
Jong Seto, Jeremy A. Horst, Dilworth Y. Parkinson, John C. Frachella, Joseph L. DeRisi

bioRxiv 152199; doi: https://doi.org/10.1101/152199 New Results
Predicting Response to Platin Chemotherapy Agents with Biochemically-inspired Machine Learning
Eliseos J Mucaki, Jonathan Z.L Zhao, Dan Lizotte, Peter K Rogan

bioRxiv 231712; doi: https://doi.org/10.1101/231712 New Results
Non-blocking modulation as the major mechanism of sodium channel inhibition by riluzole
Anett K Szabo, Krisztina Pesti, Peter Lukacs, Matyas C Foldi, Zoltan Gerevich, Beata Sperlagh, Arpad Mike

bioRxiv 228569; doi: https://doi.org/10.1101/228569 New Results
Non-blocking modulation contributes to sodium channel inhibition by a covalently attached photoreactive riluzole analog
Peter Lukacs, Matyas C Foldi, Luca Valanszki, Emilio Casanova, Beata Biri-Kovacs, Laszlo Nyitray, Andras Malnasi-Csizmadia, Arpad Mike

bioRxiv 228684; doi: https://doi.org/10.1101/228684 New Results
Propofol induces metabolic reprogramming and cell death in a mitochondrial electron transport chain-dependent manner
Chisato Sumi, Akihisa Okamoto, Hiromasa Tanaka, Kenichiro Nishi, Munenori Kusunoki, Tomohiro Shoji, Takeo Uba, Yoshiyuki Matsuo, Takehiko Adachi, Jun-Ichi Hayashi, Keizo Takenaga, Kiichi Hirota

bioRxiv 181933; doi: https://doi.org/10.1101/181933 New Results

Pharmacology and Toxicology

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