Pharmacology and Toxicology

Intrinsic structure of model-derived metrics for in silico proarrhytmic risk assessment identified by global sensitivity analysis
Jaimit Parikh, Paolo Di Achielle, James Kozloski, Viatcheslav Gurev

bioRxiv 543926; doi: https://doi.org/10.1101/543926 New Results
Environmental Assessment of Cytotoxic Drugs in the Oncology Center of Cyprus
Elpidoforos S. Soteriades, Sofia C. Economidou, Artemis Tsivitanidou, Petros Polyviou, Amanda Lorimer, Nikos Katodritis, Stavroula Theophanous-Kitiri

bioRxiv 610931; doi: https://doi.org/10.1101/610931 Confirmatory Results
Effects of MCHM on yeast metabolism
Amaury Pupo, Kang Mo Ku, Jennifer E. G. Gallagher

bioRxiv 609800; doi: https://doi.org/10.1101/609800
Identification of Kinase Inhibitors that Regulate Nuclear Receptor Nurr1 (NR4A2) Cellular Activity
Kenya L. Williams, Carrow I. Wells, John T. Moore

bioRxiv 420976; doi: https://doi.org/10.1101/420976 New Results
Identification and Characterization of the First Fragment Hits for SETDB1 Tudor Domain
Pavel Mader, Rodrigo Mendoza-Sanchez, Aman Iqbal, Aiping Dong, Elena Dobrovetsky, Victoria B. Corless, Sean K. Liew, Scott R. Houliston, Renato Ferreira De Freitas, David Smil, Carlo C. Dela Sena, Steven Kennedy, Diego B. Diaz, Hong Wu, Ludmila Dombrovski, Abdellah Allali-Hassani, Jinrong Min, Matthieu Schapira, Masoud Vedadi, Peter J. Brown, Vijayaratnam Santhakumar, Andrei K. Yudin, Cheryl H. Arrowsmith

bioRxiv 605303; doi: https://doi.org/10.1101/605303 New Results
Pharmacological inhibition of soluble epoxide hydrolase as a new therapy for Alzheimer’s Disease
Christian Griñán-Ferré, Sandra Codony, Eugènia Pujol, Jun Yang, Rosana Leiva, Carmen Escolano, Dolors Puigoriol-Illamola, Júlia Companys-Alemany, Rubén Corpas, Coral Sanfeliu, M. Isabel Loza, José Brea, Christophe Morisseau, Bruce D. Hammock, Santiago Vázquez, Mercè Pallàs, Carles Galdeano

bioRxiv 605055; doi: https://doi.org/10.1101/605055 New Results
Unequal interactions between alcohol and nicotine co-consumption: Suppression and enhancement of concurrent drug intake
Margot C DeBaker, Janna K Moen, Jenna M Robinson, Kevin Wickman, Anna M Lee

bioRxiv 601641; doi: https://doi.org/10.1101/601641
Praziquantel activates a schistosome transient receptor potential channel
Sang-Kyu Park, Paul McCusker, Peter I. Dosa, John D. Chan, Jonathan S. Marchant

bioRxiv 600791; doi: https://doi.org/10.1101/600791 New Results
Rapid discovery of drug target engagement by isothermal shift assay
Kristofor J. Webb, Kerri A. Ball, Stephen J. Coleman, Jeremy Jacobsen, Michael H.B. Stowell, William M. Old

bioRxiv 584656; doi: https://doi.org/10.1101/584656 New Results
Atropselective Oxidation of 2,2’,3,3’,4,6’-Hexachlorobiphenyl (PCB 132) to Hydroxylated Metabolites by Human Liver Microsomes and Its Implications for PCB 132 Neurotoxicity
Eric Uwimana, Brianna Cagle, Coby Yeung, Xueshu Li, Eric V. Patterson, Jonathan A. Doorn, Hans-Joachim Lehmler

bioRxiv 373837; doi: https://doi.org/10.1101/373837 New Results

Pharmacology and Toxicology

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