Pharmacology and Toxicology

Effects of Nicotine and THC Vapor Inhalation Administered by An Electronic Nicotine Delivery System (ENDS) in Male Rats
Mehrak Javadi-Paydar, Tony M Kerr, Eric L Harvey, Maury Cole, Michael A Taffe

bioRxiv 418699; doi: https://doi.org/10.1101/418699 New Results
Mitohormetic effects of rotenone drastically depend on age
Mario Baumgart, Martino Ugolini, Marco Groth, Matthias Platzer, Alessandro Cellerino

bioRxiv 528547; doi: https://doi.org/10.1101/528547 New Results
A High-Throughput Screen of a Library of Therapeutics Identifies Substrates of P-glycoprotein
Tobie D. Lee, Olivia W. Lee, Kyle R. Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G. Tebase, Carleen Klumpp-Thomas, Robert W. Robey, Suresh V. Ambudkar, Min Shen, Michael M. Gottesman, Matthew D. Hall

bioRxiv 528992; doi: https://doi.org/10.1101/528992 New Results
Biological Evaluation of Molecules of the azaBINOL Class as Antiviral Agents: Specific Inhibition of HIV-1 RNase H Activity by 7-Isopropoxy-8-(naphth-1-yl)quinoline
Ross D Overacker, Somdev Banerjee, George F Neuhaus, Selena Milicevic Sephton, Alexander Herrmann, James A Strother, Ruth Brack-Werner, Paul R Blakemore, Sandra Loesgen

bioRxiv 525105; doi: https://doi.org/10.1101/525105 New Results
Computational drug repositioning of bortezomib to reverse metastatic effect of GALNT14 in lung cancer
Ok-Seon Kwon, Haeseung Lee, Hyeon-Joon Kong, Ji Eun Park, Wooin Lee, Seungmin Kang, Mirang Kim, Wankyu Kim, Hyuk-Jin Cha

bioRxiv 394163; doi: https://doi.org/10.1101/394163 New Results
Scavenging of reactive dicarbonyls with 2-hydroxybenzylamine reduces atherosclerosis in hypercholesterolemic Ldlr-/- mice
Huan Tao, Jiansheng Huang, Patricia G Yancey, Lei Ding, Youmin Zhang, John L Blakemore, Venkataraman Amarnath, John A Oates, L Jackson Roberts II, Sean S Davies, MacRae F Linton

bioRxiv 524884; doi: https://doi.org/10.1101/524884 New Results
The off-target kinase landscape of clinical PARP inhibitors
Albert A. Antolin, Malaka Ameratunga, Udai Banerji, Paul Clarke, Paul Workman, Bissan Al-Lazikani

bioRxiv 520023; doi: https://doi.org/10.1101/520023 New Results
A Data-Driven Transcriptional Taxonomy of Adipogenic Chemicals to Identify Emerging Metabolic Health Threats
Stephanie Kim, Eric Reed, Stefano Monti, Jennifer Schlezinger

bioRxiv 519629; doi: https://doi.org/10.1101/519629 New Results
Behavioural Evaluation of the Anticonvulsant Properties of the Traditional Medicine Anonna Senegalensis on Parabss Drosophila melanogaster Mutants.
Samuel Dare, Emiliano Merlo, Peter E Ekanem, Jimena Berni

bioRxiv 519322; doi: https://doi.org/10.1101/519322 New Results
Reversible silencing of endogenous receptors in intact brain tissue using two-photon pharmacology
Silvia Pittolo, Hyojung Lee, Anna Lladó, Sébastien Tosi, Miquel Bosch, Lídia Bardia, Xavier Gómez-Santacana, Amadeu Llebaria, Eduardo Soriano, Julien Colombelli, Kira E Poskanzer, Gertrudis Perea, Pau Gorostiza

bioRxiv 515288; doi: https://doi.org/10.1101/515288 New Results

Pharmacology and Toxicology

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