Pharmacology and Toxicology

Effects of rhein on bile acid homeostasis in rats
Zhong Xian, Jingzhuo Tian, Lianmei Wang, Yushi Zhang, Jiayin Han, Nuo Deng, Suyan Liu, Yong Zhao, Chunying Li, Yan Yi, Dunfang Wang, Jing Meng, Chen Pan, Aihua Liang

bioRxiv 2020.01.29.925297; doi: https://doi.org/10.1101/2020.01.29.925297 New Results

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Reconstituted Mining Effluent Reduces Neuronal Proliferation in the Developing Brain and Slows Growth of Body and Facial Features in Wild-Caught Wood Frog Tadpoles
Hannah G. Sturgeon, Jeremy P. Kitchen, Lara I. Dahora, Sara E. Sweeten, Christopher K. Thompson

bioRxiv 2020.01.29.924837; doi: https://doi.org/10.1101/2020.01.29.924837 New Results

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Acute oral toxicity and risks of exposure to the neonicotinoid thiamethoxam, and other classes of systemic insecticide, for the Common Eastern Bumblebee (Bombus impatiens)
Kayla A. Mundy-Heisz, Ryan S. Prosser, Nigel E. Raine

bioRxiv 2020.01.27.921510; doi: https://doi.org/10.1101/2020.01.27.921510 New Results

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Sex-associated differences in cytomegalovirus prevention: Prophylactic strategy is associated with a strong kidney function impairment in female renal transplant patients
Arturo Blazquez-Navarro, Chantip Dang-Heine, Chris Bauer, Nicole Wittenbrink, Kerstin Wolk, Robert Sabat, Oliver Witzke, Timm H. Westhoff, Birgit Sawitzki, Petra Reinke, Oliver Thomusch, Christian Hugo, Nina Babel, Michal Or-Guil

bioRxiv 726968; doi: https://doi.org/10.1101/726968 New Results

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Therapeutic Drugs Targeting 2019-nCoV Main Protease by High-Throughput Screening
Yan Li, Jinyong Zhang, Ning Wang, Haibo Li, Yun Shi, Gang Guo, Kaiyun Liu, Hao Zeng, Quanming Zou

bioRxiv 2020.01.28.922922; doi: https://doi.org/10.1101/2020.01.28.922922 New Results

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Integrated Analysis of Methylome and Transcriptome Following Developmental Atrazine Exposure in Zebrafish Reveals Aberrant Gene-Specific Methylation of Neuroendocrine and Reproductive Pathways
Chris Bryan, Li Lin, Junkai Xie, Janiel Ahkin Chin Tai, Katharine A. Horzmann, Kyle Wettschurack, Min Zhang, Jennifer Freeman, Chongli Yuan

bioRxiv 2020.01.28.922179; doi: https://doi.org/10.1101/2020.01.28.922179 New Results

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Sex dependent compensatory mechanisms to preserve blood pressure homeostasis in PGI₂ receptor deficient mice
Soon Yew Tang, Seán T. Anderson, Hu Meng, Dimitra Sarantopoulou, Emanuela Ricciotti, Elizabeth J. Hennessy, Gregory R. Grant, Garret A. FitzGerald

bioRxiv 2020.01.27.921791; doi: https://doi.org/10.1101/2020.01.27.921791 New Results

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Curcumin Analogues as the Inhibitors of TLR4 Pathway in Inflammation and Their Drug Like Potentialities: A Computer-based Study
Md. Asad Ullah, Fatema Tuz Johora, Bishajit Sarkar, Yusha Araf, MD. Hasanur Rahman

bioRxiv 2020.01.27.921528; doi: https://doi.org/10.1101/2020.01.27.921528 New Results

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Nelfinavir was predicted to be a potential inhibitor of 2019-nCov main protease by an integrative approach combining homology modelling, molecular docking and binding free energy calculation
Zhijian Xu, Cheng Peng, Yulong Shi, Zhengdan Zhu, Kaijie Mu, Xiaoyu Wang, Weiliang Zhu

bioRxiv 2020.01.27.921627; doi: https://doi.org/10.1101/2020.01.27.921627 New Results

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Testing of the survivin suppressant YM155 in a large panel of drug-resistant neuroblastoma cell lines
Martin Michaelis, Yvonne Voges, Florian Rothweiler, Fabian Weipert, Amara Zia-Ahmad, Jaroslav Cinatl, Andreas von Deimling, Frank Westermann, Franz Rödel, Mark N. Wass, Jindrich Cinatl jr.

bioRxiv 2020.01.27.921312; doi: https://doi.org/10.1101/2020.01.27.921312 New Results

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Pharmacology and Toxicology

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